Inventor

Craig A. Rosen

Inventor

Laytonsville, MD, US

Overview

1988–2016

Patent span

Chemistry

Primary field (CPC C)

Patents· 341 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Kprimary

C07KPeptides30%

A61KPreparations for medical, dental or toiletry purposes25%

C12NMicroorganisms or enzymes15%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations14%

G01NInvestigating or analysing materials by determining their chemical or physical properties5%

Y02ATechnologies for adaptation to climate change3%

Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests2%

A01KAnimal husbandry2%

C12YEnzymes2%

C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms1%

PatentTitleYear

9,505,823'Albumin-insulin fusion proteins'2016 9,416,185'Humanized antibodies against TL1A'2016 9,403,905'Vascular endothelial growth factor 2'2016 9,296,809'Albumin fusion proteins'2016 9,221,896'Albumin fusion proteins'2015 8,993,517'Albumin fusion proteins'2015 8,969,538'Albumin fusion proteins'2015 8,784,809'Vascular endothelial growth factor 2'2014 8,728,482'Humanized antibodies against TL1A'2014 8,524,869'Humanized antibodies against LIGHT and uses thereof'2013 8,513,189'Albumin fusion proteins'2013 8,410,248'HWBAO62 polypeptides'2013 8,334,365'Albumin fusion proteins'2012 8,329,179'Death domain containing receptor 4 antibodies and methods'2012 8,287,859'Methods of reducing toxicity and effects of cocaine by administering a butyrylcholinesterase (BChE)-albumin fusion protein'2012 8,263,743'Humanized antibodies against TL1A'2012 8,252,739'Albumin fusion proteins'2012 8,216,569'Vascular endothelial growth factor 2'2012 8,211,439'Albumin fusion proteins comprising insulin polypeptides'2012 8,206,708'Vascular endothelial growth factor 2'2012 8,168,205'Streptococcus pneumoniae polypeptides'2012 8,143,026'Albumin fusion proteins'2012 8,106,165'Antibodies to HNFIP24 polypeptides'2012 8,093,363'Tumor necrosis factor-gamma'2012 8,071,539'Albumin fusion proteins'2011 8,012,464'G-CSF-albumin fusion proteins'2011 7,977,306'Albumin fusion proteins'2011 7,973,139'Antibodies against nogo receptor'2011 7,968,689'Antibodies to HSDEK49 polypeptides'2011 7,943,741'Antibodies that specifically bind to chemokine Î²-4'2011 7,932,361'Antibodies to HT5GJ57'2011 7,914,789'HEMCM42 antibodies'2011 7,910,321'Methods of determining the level of human tumor necrosis factor receptor-like 2'2011 7,906,634'HEMCM42 nucleic acids'2011 7,906,119'Antibodies against protective antigen'2011 7,862,818'Method of inhibiting human G-protein chemokine receptor (CCR5) HDGNR10'2011 7,851,596'Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides'2010 7,850,963'Vascular endothelial growth factor 2'2010 7,847,079'Albumin fusion proteins'2010 7,838,636'Antibodies to HWHGU54 polypeptides'2010 7,829,293'Antibodies to chemokine Î²-15'2010 7,824,675'Use of an antibody that binds human tumor necrosis factor receptor-like 2'2010 7,820,798'Tumor necrosis factor-gamma'2010 7,816,091'Method of identifying a binding partner to a cytokine receptor common gamma chain like polypeptide'2010 7,803,615'Death domain containing receptor 5'2010 7,799,759'Albumin fusion proteins'2010 7,781,176'Antibodies to HTEEB42 protein'2010 7,763,244'Antibodies that specifically bind to Reg IV'2010 7,741,055'Prostatic growth factor'2010 7,601,351'Antibodies against protective antigen'2009 7,597,886'Tumor necrosis factor-gamma'2009 7,592,010'Albumin fusion proteins'2009 7,576,189'Antibodies to human vascular endothelial growth factor 2 and methods of using the same'2009 7,569,384'Albumin fusion proteins'2009 7,541,441'Antibodies that specifically bind to TL5'2009 7,524,501'Methods of treating an injury to, or disorder of, the eye involving photoreceptor proliferation by administering VEGF2 antibodies'2009 7,521,424'Albumin fusion proteins'2009 7,514,079'Antibodies that specifically bind to neurokinin B'2009 7,514,081'Methods of inhibiting an immune response with anti-human endokine alpha antibodies'2009 7,507,414'Albumin fusion proteins'2009 7,507,413'Albumin fusion proteins'2009 7,504,105'Treatment using antibodies to cytokine receptor common gamma chain like'2009 7,501,123'Human G-protein chemokine receptor (CCR5) HDGNR10'2009 7,498,417'Antibodies to vascular endothelial growth factor 2 and methods of using same'2009 7,482,442'HEMCM42 nucleic acids'2009 7,482,326'Endothelial-monocyte activating polypeptide III'2009 7,476,384'Death domain containing receptor 4 antibody and methods'2009 7,465,707'Methods of treatment with TR10 polypeptides'2008 7,459,531'50 Human secreted proteins'2008 7,452,538'Death domain containing receptor 4 antibodies and methods'2008 7,446,169'Human tumor necrosis factor receptor-like 2'2008 7,439,333'Vascular endothelial growth factor 2'2008 7,429,646'Antibodies to human tumor necrosis factor receptor-like 2'2008 7,427,492'Polynucleotides encoding human tumor necrosis factor receptor-like2'2008 7,425,622'Antibodies against C3a receptor'2008 7,416,855'Immunoassay methods for detecting interleukin-1 Î² converting enzyme like apoptosis protease-3'2008 7,411,051'Antibodies to HDPPA04 polypeptide'2008 7,402,312'Antibodies to vascular endothelial growth factor 2 (VEGF-2)'2008 7,393,650'Method of producing an antibody to G-protein parathyroid hormone receptor HLTDG74'2008 7,393,934'Human G-protein chemokine receptor (CCR5) HDGNR10'2008 7,390,880'Soluble interleukin-1 receptor accessory molecule'2008 7,375,192'Antibodies that specifically bind to chemokine beta-4'2008 7,374,764'CD33-like protein'2008 7,368,244'Peptidoglycan recognition proteins'2008 7,368,527'HADDE71 polypeptides'2008 7,368,531'Human secreted proteins'2008 7,364,865'Antibodies to myeloid progenitor inhibitory factor-1 (MPIF-1)'2008 7,361,341'Methods of treating cancer using antibodies that immunospecifically bind to trail receptors'2008 7,348,003'Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors'2008 7,335,489'Polynucleotides encoding a protein kinase C inhibitor protein and methods of using these polynucleotides'2008 7,320,869'Antibodies to Chemokine Alpha-5'2008 7,282,351'Prostatic growth factor'2007 7,247,442'Antibodies to HHPEN62 polypeptide'2007 7,238,660'Albumin fusion proteins'2007 7,238,667'Albumin fusion proteins'2007 7,227,005'Vascular endothelial growth factor 2'2007 7,223,724'Use of vascular endothelial growth factor to treat photoreceptor cells'2007 7,217,529'Antibodies to chemokine Alpha-6'2007 7,217,528'Antibodies to HFXJW48 polypeptide'2007 7,208,584'Fibroblast growth factor-13'2007 7,208,582'Vascular endothelial growth factor 2'2007 7,196,164'Secreted protein HHTLF25'2007 7,189,690'Albumin fusion proteins'2007 7,186,688'Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2'2007 7,175,988'Human G-protein Chemokine Receptor (CCR5) HDGNR10'2007 7,169,566'Metalloproteinases'2007 7,169,565'Antibodies to HASAV70 polypeptide'2007 7,163,797'50 human secreted proteins'2007 7,153,942'Vascular endothelial growth factor 2'2006 7,153,827'Vascular endothelial growth factor 2 and methods of use'2006 7,141,547'Albumin fusion proteins comprising GLP-1 polypeptides'2006 7,141,418'Streptococcus pneumoniae polynucleotides and sequences'2006 7,135,551'Chemokine Î²-15'2006 7,115,392'Polynucleotides encoding human vascular endothelial growth factor 2'2006 7,109,308'Antibodies to human vascular endothelial growth factor 2'2006 7,105,644'Secreted protein HHTLF25 antibodies'2006 7,098,316'Human proteins'2006 7,091,315'Protein HDPBQ71'2006 7,087,225'Methods and compositions for treating metabolic bone diseases relating to human endokine alpha'2006 7,083,930'Human choline acetyltransferase'2006 7,078,027'Human endokine alpha'2006 7,071,309'Antibodies to breast specific gene 1'2006 7,064,189'Antibodies that immunospecifically bind to trail receptors'2006 7,060,261'Chemokine Î±-5'2006 7,060,272'Death domain containing receptor-4 agonist antibodies and methods'2006 7,056,516'I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis'2006 7,056,681'Interleukin-19 antibodies'2006 7,056,510'Streptococcus pneumoniae SP036 polynucleotides, polypeptides, antigens and vaccines'2006 7,053,190'Secreted protein HRGDF73'2006 7,049,081'Diagnostic methods based on human BTG-2 and BTG-3 polypeptides'2006 7,045,496'Use of vascular endothelial growth factor to treat photoreceptor cells'2006 7,045,301'Endothelial-monocyte activating polypeptide III antibodies'2006 7,041,802'Peptidoglycan recognition proteins'2006 7,041,803'Galectin 11'2006 7,041,460'Antibodies to monocyte-colony inhibitory factor (M-CIF)'2006 7,026,447'53 human secreted proteins'2006 7,008,778'Breast cancer specific gene 1'2006 7,001,992'Antibodies to secreted protein HEMCM42'2006 6,994,857'Albumin fusion proteins'2006 6,982,320'Cytokine receptor common gamma chain like'2006 6,979,443'Chemokine Î±-6'2005 6,974,682'Soluble interleukin-1 receptor accessory molecule'2005 6,969,599'Nucleic acids encoding tumor necrosis factor receptor TR10'2005 6,953,667'Antibodies against human protein HUVDJ43'2005 6,951,924'Antibodies against secreted protein HTEBYII'2005 6,946,134'Albumin fusion proteins'2005 6,943,020'Death domain containing receptor-4 antibodies'2005 6,936,691'Secreted protein HCE3C63'2005 6,929,930'Streptococcus pneumoniae SP042 polynucleotides'2005 6,926,898'Albumin fusion proteins'2005 6,924,356'Human protein HHEPU32'2005 6,919,433'Antibodies to protein HPMBQ91'2005 6,916,629'Tissue factor pathway inhibitor-3'2005 6,914,047'Secreted protein HEMAE80'2005 6,905,688'Albumin fusion proteins'2005 6,902,910'Death domain containing receptor 4'2005 6,900,033'Methods and compositions for modulating ACE-2 activity'2005 6,887,663'Streptococcus pneumoniae SP036 polynucleotides'2005 6,881,823'Human protein HFXJW48'2005 6,881,401'Methods of treatment of immune system related disorders using Neutrokine-alpha'2005 6,878,806'Human secreted protein HTEEB42'2005 6,878,812'Metalloproteinases'2005 6,878,687'Protein HMAAD57'2005 6,872,568'Death domain containing receptor 5 antibodies'2005 6,864,226'Endothelial-monocyte activating polypeptide III'2005 6,861,227'Antibodies to cytokine receptor common gamma chain like'2005 6,849,436'Human hypoxanthine-(guanine) phosphoribosyl transferase-2'2005 6,844,170'Cytokine receptor common gamma chain like'2005 6,835,555'Interleukin-1 converting enzyme like apoptosis protease-3 and 4'2004 6,831,152'Colon specific genes and proteins'2004 6,828,424'Human tissue inhibitor of metalloproteinase-4'2004 6,824,767'Tumor necrosis factor-gamma'2004 6,824,993'Antibodies that bind human prostate specific G-protein receptor HPRAJ70'2004 6,811,773'Human monocyte colony inhibitory factor (M-CIF) polypeptides'2004 6,812,327'Neutrokine-alpha polypeptides'2004 6,806,351'Secreted protein HBJFE12'2004 6,790,826'Human haemopoietic maturation factor'2004 6,774,216'Antibodies to secreted protein HCEJQ69'2004 6,743,625'Death domain containing receptor 5'2004 6,737,248'Staphylococcus aureus polynucleotides and sequences'2004 6,734,285'Vascular endothelial growth factor 2 proteins and compositions'2004 6,733,981'Antibodies to interleukin-1 converting enzyme like apoptosis protease-3 and 4'2004 6,689,360'Human B-cell translocation genes-2 and 3 antibodies'2004 6,680,171'I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis'2004 6,656,743'Human choline acetyltransferase'2003 6,653,446'Human hypoxanthine- (guanine) phosphoribosyl transferase-2'2003 6,653,445'Human CCV polypeptides'2003 6,635,252'Antibodies to superoxide dismutase-4'2003 6,635,482'Monoclonal antibodies to membrane neutrokine-'2003 6,632,920'36 human secreted proteins'2003 6,630,443'Human amine transporter antibodies'2003 6,627,741'Antibodies to secreted protein HCEJQ69'2003 6,623,938'I-flice, a novel inhibitor of tumor necrosis factor receptor-1 and CD-95 induced apoptosis'2003 6,620,619'Human DNA mismatch repair protein'2003 6,617,132'Human cystatin E polynucleotides'2003 6,610,477'Human DNA mismatch repair proteins'2003 6,608,182'Human vascular endothelial growth factor 2'2003 6,607,726'Human tumor necrosis factor receptor TR10'2003 6,605,699'Galectin-11 polypeptides'2003 6,605,441'Antibodies against fibroblast growth factor 11'2003 6,605,592'Protein HOFNF53'2003 6,599,719'Nucleic acid molecules encoding tumor necrosis factor-gamma-alpha'2003 6,593,114'Staphylococcus aureus polynucleotides and sequences'2003 6,593,112'Polynucleotides encoding fibroblast growth factor 15'2003 6,590,088'CD33-like protein'2003 6,590,075'Secreted protein HODAZ50'2003 6,583,270'Interleukin-19'2003 6,573,082'Streptococcus pneumoniae antigens and vaccines'2003 6,569,992'Protein HLQDR48'2003 6,569,660'Human DNase'2003 6,566,328'Human growth hormone'2003 6,566,325'49 human secreted proteins'2003 6,562,579'Diagnostic methods using antibodies to Neutrokine-alpha'2003 6,548,262'Methods of measuring tissue factor pathway inhibitor-3'2003 6,544,761'Human tissue inhibitor of metalloproteinase-4'2003 6,538,121'Interleukin-1 converting enzyme like apoptosis protease-3 and 4'2003 6,534,631'Secreted protein HT5GJ57'2003 6,531,447'Secreted protein HEMCM42'2003 6,525,174'Precerebellin-like protein'2003 6,521,742'Human endokine alpha'2003 6,521,227'Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides'2003 6,518,404'Human endothelin-bombesin receptor antibodies'2003 6,506,569'Antibodies to human tumor necrosis factor receptor TR10'2003 6,503,735'Polynucleotides encoding chemokine -15'2003 6,500,638'Prostatic growth factor'2002 6,495,519'Interleukin-1 converting enzyme like apoptosis protease-3 and 4'2002 6,486,301'Interleukin-20'2002 6,482,408'Fibroblast growth factor 15 antibodies'2002 6,482,606'Human DNA mismatch repair polynucleotides'2002 6,476,195'Secreted protein HNFGF20'2002 6,475,753'94 Human Secreted Proteins'2002 6,461,823'Death domain containing receptor-4 antibodies'2002 6,451,577'Human uridine disphosphate galactose-4-epimerase'2002 6,448,230'Testis expressed polypeptide'2002 6,448,042'Human tissue inhibitor of metalloproteinase-4'2002 6,444,790'Peptidoglycan recognition proteins'2002 6,432,708'Human choline acetyltransferase'2002 6,433,139'Secreted protein HPEAD48'2002 6,433,147'Death domain containing receptor-4'2002 6,420,135'Streptococcus pneumoniae polynucleotides and sequences'2002 6,420,526'186 human secreted proteins'2002 6,416,984'Human DNA mismatch repair proteins'2002 6,410,709'Cornichon-like protein'2002 6,410,701'Human neuropeptide receptor'2002 6,406,867'Antibody to human endokine alpha and methods of use'2002 6,403,557'Fibroblast growth factor-13'2002 6,403,770'Antibodies to neutrokine-alpha'2002 6,395,514'Polynucleotides encoding chemokine-5'2002 6,391,853'Human tissue inhibitor of metalloproteinase-4'2002 6,380,369'Human DNA mismatch repair proteins'2002 6,372,456'Polynucleotides encoding chemokine -6'2002 6,372,891'Human G-protein receptor HPRAJ70'2002 6,368,822'Fibroblast growth factor 13'2002 6,365,369'Prostate specific secreted protein'2002 6,346,246'Antibodies that bind human haemopoietic maturation factor'2002 6,344,543'Human transcription factor IIA'2002 6,344,198'Human prostatic specific reductase'2002 6,342,363'Death domain containing receptor 4 nucleic acids and methods'2002 6,342,581'Secreted protein HLHFP03'2002 6,338,951'G-protein parathyroid hormone receptor HLTDG74'2002 6,337,195'Colon specific genes and proteins'2002 6,319,700'Human choline acetyltransferase'2001 6,312,937'Metalloproteinases'2001 6,300,310'Human tissue inhibitor of metalloproteinase- 4'2001 6,300,477'Antibodies to human cystatin E'2001 6,294,164'Natural killer cell enhancing factor C'2001 6,287,812'Nucleic acid molecules encoding cytostatin I'2001 6,262,233'Tissue factor pathway inhibitor-3'2001 6,258,777'Human B-cell translocation genes-2 and 3'2001 6,255,079'Polynucleotides encoding natural killer cell enhancing factor C'2001 6,251,648'Gene encoding human Dnase'2001 6,245,540'Human choline acetyltransferase'2001 6,214,580'Human tumor necrosis factor receptor tr10'2001 6,159,469'Streptococcus pneumoniae antigens and vaccines'2000 6,156,540'Thrombin inhibitor'2000 6,153,739'Polynucleotides encoding human uridine diphosphate galactose-4-epimerase'2000 6,143,519'Human endothelin-bombesin receptor'2000 6,133,422'Thrombin inhibitor'2000 6,117,426'Human amine transporter polypeptide fragments'2000 6,110,893'Fibroblast growth factor 11'2000 6,106,829'Human prostatic specific reductase'2000 6,090,575'Polynucleotides encoding human G-protein coupled receptor GPR1'2000 6,087,150'Interleukin-1 .beta. converting enzyme like apoptosis protease-3 and 4'2000 6,046,031'Metalloproteinases'2000 6,040,157'Vascular endothelial growth factor 2'2000 6,030,804'Polynucleotides encoding G-protein parathyroid hormone receptor HLTDG74 polypeptides'2000 6,013,483'DNA encoding endothelial monocyte activating polypeptide III'2000 6,013,469'Human B-cell translocation genes-2 and 3'2000 6,013,477'Fibroblast growth factor 15'2000 6,011,012'Human cystatin E'2000 6,008,042'Interleukin-1 beta converting enzyme like apoptotic protease-7'1999 5,998,171'Polynucleotides encoding human endokine alpha'1999 5,998,164'Polynucleotides encoding human G-protein coupled receptor GPRZ'1999 5,994,102'Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides'1999 5,994,302'Human vascular IBP-like growth factor'1999 5,986,069'Human haemopoietic maturation factor polypeptides'1999 5,985,614'Polynucleotides encoding interleukin-19'1999 5,985,612'Polynucleotides encoding natural killer cell enhancing factor C'1999 5,985,601'DNA encoding human cystatin E'1999 5,981,231'Polynucleotides encoding chemokine .beta.-15'1999

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1988–1998Based in Brookline, MA, US· patent location history

1995–1997Based in Glen Ridge, NJ, US· patent location history

1996–2016Patents assigned to HUMAN GENOME SCIENCES INC (313)· patent assignee history

1996–2016Based in Laytonsville, MD, US· patent location history

1998–2011Patents assigned to SMITHKLINE BEECHAM CORP (7)· patent assignee history

1999–2012Patents assigned to UNIV MICHIGAN (11)· patent assignee history

1999–2014Based in Rockville, MD, US· patent location history

2011–2016Patents assigned to ROSEN CRAIG A (15)· patent assignee history

2011–2013Patents assigned to RUBEN STEVEN M (9)· patent assignee history

2011–2016Based in Pasadena, MD, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
HUMAN GENOME SCIENCES INC	313	1996–2016
ROSEN CRAIG Aself	15	2011–2016
UNIV MICHIGAN	11	1999–2012
RUBEN STEVEN M	9	2011–2013
SMITHKLINE BEECHAM CORP	7	1998–2011

Locations

Location	Patents	Span
Laytonsville, Maryland, US	309	1996–2016
Pasadena, Maryland, US	19	2011–2016
Brookline, Massachusetts, US	5	1988–1998
Rockville, Maryland, US	3	1999–2014
Glen Ridge, New Jersey, US	3	1995–1997