Methods for inhibiting HIV-1 infection
Granted 2 May 2006 · 6 office actions
Current assignee: Progenics Pharmaceuticals · originally Lantheus Holdings, Inc.
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Inventors: William C. Olson, Paul J. Maddon · Examiner: Jeffrey Stucker · AU 1648 · TC 1600
Life of the application
19 dated eventsAbstract
This invention provides a method of reducing an HIV infected subject\'s HIV-1 viral load which comprises administering to the subject an effective viral load reducing amount of an antibody which (a) binds to a CCR5 chemokine receptor and (b) inhibits fusion of HIV-1 to a CD4+CCR5+ cell, so as to thereby reduce the subject\'s HIV-1 viral load to 50% or less of the subject\'s HIV-1 viral load prior to administering the antibody to the subject.
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12 codes- A61K39/395
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