USPatent applicationPatented

Integrated method for PCR cleanup and oligonucleotide removal

Granted 6 Jun 2006 · 3 office actions

Current assignee: Thermo Fisher Scientific · originally Applera Corporation

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Inventors: Lawrence Greenfield, Douglas A. Bost · Examiner: Joyce Tung

Life of the application

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Abstract

A method is provided for purifying a desired polynucleotide product by removing unincorporated oligonucleotides from a polymerase or ligase reaction mixture.

Claims as granted

62 claims

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Classifications

8 codes
IPC · International Patent Classification
Section C — Chemistry; metallurgy
  • C07H21/04
  • C12P19/34
Section G — Physics
  • G01N1/68
USPC · US Patent Classification
435/6435/91.2536/25.4536/23.1435/91.1

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File wrapper

⤢ drag to zoomJul 2002Jan 2003Jul 2003Jan 2004Jul 2004Jan 2005Jul 2005Jan 2006Jul 2006USPTOApplicantNon-final rejectionNotice of allowanceRequest for continued examination
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Pendency
3.9 y
1,414 days filing → grant
Office actions
1
non-final + final
Responses
1
1 RCE
Interviews
1
examiner interview summaries
Examiner
Joyce Tung
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Citations: 11 back · 0 forward

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Documents

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