Inventor
Raghavan Rajagopalan
Inventor
Maryland Heights, MO, US
Overview
Patents· 112 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Kprimary
A61KPreparations for medical, dental or toiletry purposes34%
C07DHeterocyclic compounds18%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations15%
C09BOrganic dyes or closely-related compounds for producing dyes, e.g. pigments8%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium5%
C07KPeptides4%
C07BGeneral methods of organic chemistry3%
C07CAcyclic or carbocyclic compounds3%
Y10TTechnical subjects covered by former us classification3%
Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests2%
PatentTitleYear
10,988,500Lipid A mimics, methods of preparation, and uses thereof202110,695,445Methods of using optical agents202010,617,687Fluorescent pyrazine derivatives and methods of using the same in assessing renal function202010,370,362Pyrazine derivatives with extended conjugation and methods of using the same in optical applications2019RE047413Pyrazine derivatives and uses thereof in renal monitoring2019RE047255Pyrazine derivatives and uses thereof in renal monitoring201910,137,207Methods of using optical agents201810,059,739Non-benzenoid aromatic systems for imaging, monitoring and therapy20189,777,022'Process for the preparation of macrocyclic polyazacarboxylate ligands and chelates'20179,527,858'Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers'20169,518,062'Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers'20169,480,687'Pyrazine derivatives and uses thereof in renal monitoring'20169,433,700'Tissue sealant compositions, vascular closure devices, and uses thereof'20169,376,399'Fluorescent pyrazine derivatives and methods of using the same in assessing renal function'20169,315,474'Process for the preparation of macrocyclic polyazacarboxylate ligands and chelates'20169,283,288'Methods of using optical agents'20169,226,980'Azulene and azaazulene systems for imaging, monitoring and therapy'20169,216,963'Pyrazine derivatives with extended conjugation and methods of using the same in optical applications'20159,186,349'Diaza heterocyclic compounds for phototherapy'20159,114,160'Pyrazine derivatives and uses thereof in renal monitoring'20158,829,020'Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers'20148,778,309'Fluorescent pyrazine derivatives and methods of using the same in assessing renal function'20148,731,655'Compounds containing acyclic N-N bonds for phototherapy'20148,722,685'Pyrazine derivatives and uses thereof in renal monitoring'20148,664,392'Pyrazine derivatives for bioconjugation'20148,658,433'Dye compounds as photoactive agents'20148,481,734'Pyrazine derivatives and uses thereof, including in medical imaging and visualization applications'20138,313,729'Integrated photoactive small molecules and uses thereof'20128,115,000'Pyrazine derivatives and uses thereof in renal monitoring'20127,888,378'Thiadiazole compounds and uses thereof'20117,790,144'Receptor-avid exogenous optical contrast and therapeutic agents'20107,767,194'Optical diagnostic and therapeutic agents and compositions'20107,758,861'Dye-sulfenates for dual phototherapy'20107,674,902'Luminescent metal complexes for monitoring renal function'20107,608,244'Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients'20097,566,444'Versatile hydrophilic dyes'20097,556,797'Minimally invasive physiological function monitoring agents'20097,514,069'Tumor-targeted optical contrast agents'20097,510,700'Pathological tissue detection and treatment employing targeted benzoindole optical agents'20097,504,087'Receptor-avid exogenous optical contrast and therapeutic agents'20097,468,177'Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients'20087,438,894'Dyes for organ function monitoring'20087,431,925'Internal image antibodies for optical imaging and therapy'20087,427,657'Aromatic sulfenates for type 1 phototherapy'20087,351,807'Cyanine-sulfenates for dual phototherapy'20087,303,926'Methods and compositions for dual phototherapy'20077,297,325'Hydrophilic light absorbing compositions for determination of physiological function'20077,294,738'Phosphorous containing steroid mimics'20077,252,815'Pathological tissue detection and treatment employing targeted benzoindole optical agents'20077,235,685'Aromatic sulfenates for type I phototherapy'20077,230,088'Compounds for dual photodiagnosis and therapy'20077,201,892'Pathological tissue detection and treatment employing targeted optical agents'20077,198,778'Tumor-targeted optical contrast agents'20077,175,831'Light sensitive compounds for instant determination of organ function'20077,128,896'Pathological tissue detection and treatment employing targeted benzoindole optical agents'20067,011,817'Hydrophilic cyanine dyes'20066,939,532'Versatile hydrophilic dyes'20056,887,854'Compounds as dynamic organ function monitoring agents'20056,761,878'Pathological tissue detection and treatment employing targeted benzoindole optical agents'20046,747,151'Azo compounds for type I phototherapy'20046,733,744'Indole compounds as minimally invasive physiological function monitoring agents'20046,716,413'Indole compounds as tissue-specific exogenous optical agents'20046,706,254'Receptor-avid exogenous optical contrast and therapeutic agents'20046,673,334'Light sensitive compounds for instant determination of organ function'20046,669,926'Hydrophilic light absorbing indole compounds for determination of physiological function in critically ill patients'20036,663,847'Dynamic organ function monitoring agents'20036,664,367'Stable analogs of bioactive peptides containing disulfide linkages'20036,656,451'Indole compounds as novel dyes for organ function monitoring'20036,641,798'Tumor-targeted optical contrast agents'20036,485,704'Azo compound for type I pototherapy'20026,423,547'Non-covalent bioconjugates useful for diagnosis and therapy'20026,395,257'Dendrimer precursor dyes for imaging'20026,280,703'Simultaneous multimodal measurement of physiological function'20016,277,841'Quinoline ligands and metal complexes for diagnosis and therapy'20016,264,920'Tunable indocyanine dyes for biomedical applications'20016,264,919'Indocyanine dyes'20016,228,344'Method of measuring physiological function'20016,217,848'Cyanine and indocyanine dye bioconjugates for biomedical applications'20016,190,641'Indocyanine dyes'20016,183,726'Versatile hydrophilic dyes'20016,180,085'Dyes'20016,180,086'Hydrophilic cyanine dyes'20016,180,087'Tunable indocyanine dyes for biomedical applications'20015,908,931'Preorganized hexadentate ligands useful in radiographic imaging agents'19995,753,205'Radiolabelled peptide compounds'19985,723,104'Monocyclic functional dyes for contrast enhancement in optical imaging'19985,709,845'Tricyclic functional dyes for contrast enhancement in optical imaging'19985,672,333'Delta.sup.1,6 bicyclo ›4,4,0! functional dyes for contrast enhancement in optical imaging'19975,672,332'Delta 1,2 bicyclo›4,4,0! functional dyes for contrast enhancement in optical imaging'19975,656,253'Ligands useful in radiographic imaging'19975,653,958'Imidazole based nitrogen-sulfur ligands useful in radiographic imaging agents'19975,648,060'Preorganized hexadentate ligands useful in radiographic imaging agents'19975,645,814'Hexadentate complexes useful in radiographic imaging agents'19975,633,372'Heterocycle based nitrogen sulfur ligands useful in radiographic imaging agents'19975,623,077'Imidazole based nitrogen sulfur ligands useful in radiographic imaging agents'19975,602,236'Metal-containing steroid mimics and ligands useful in the preparation thereof'19975,554,357'Magnetic resonance imaging agents containing hydrazide moieties'19965,464,934'Metal chelates as spacer compounds in biologically active peptides'19955,384,108'Magnetic resonance imaging agents'19955,382,654'Radiolabelled peptide compounds'19955,376,358'Magnetic resonance imaging agents'19945,376,357'Magnetic resonance imaging agents'19945,371,184'Radiolabelled peptide compounds'19945,362,477'19F magnetic resonance imaging agents which include a nitroxide moiety'19945,338,864'Hexadentate ligands useful in radiographic imaging agents'19945,330,737'Nitrogen-sulfur ligands as opiate receptor drug mimics'19945,314,680'Polyazamacrocycles for magnetic resonance imaging'19945,243,073'Hexadentate ligands useful in radiographic imaging agents'19935,217,706'Complexes and compositions for magnetic resonance imaging'19935,162,109'Magnetic resonance imaging agents'19925,141,740'Complexes and compositions for magnetic resonance imaging and usage methods'19925,011,925'Morpholinoamido EDTA derivatives'1991Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1991–2011Patents assigned to MALLINCKRODT INC (52)· patent assignee history
1991–2009Based in Maryland Heights, MO, US· patent location history
1992–1998Patents assigned to MALLINCKRODT MEDICAL INC (25)· patent assignee history
2004–2020Based in Solon, OH, US· patent location history
2004–2009Based in Woodmere, OH, US· patent location history
2007–2016Patents assigned to RAJAGOPALAN RAGHAVAN (15)· patent assignee history
2007–2014Based in Beechwood, OH, US· patent location history
2012–2016Patents assigned to DORSHOW RICHARD B (11)· patent assignee history
2012–2019Based in St. Peters, MO, US· patent location history
2015–2020Patents assigned to MEDIBEACON INC (12)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| MALLINCKRODT INC | 52 | 1991–2011 |
| MALLINCKRODT MEDICAL INC | 25 | 1992–1998 |
| RAJAGOPALAN RAGHAVANself | 15 | 2007–2016 |
| MEDIBEACON INC | 12 | 2015–2020 |
| DORSHOW RICHARD B | 11 | 2012–2016 |
Locations
| Location | Patents | Span |
|---|---|---|
| Maryland Heights, MO, US | 54 | 1991–2009 |
| Solon, OH, US | 26 | 2004–2020 |
| St. Peters, MO, US | 14 | 2012–2019 |
| Beechwood, OH, US | 7 | 2007–2014 |
| Woodmere, OH, US | 5 | 2004–2009 |