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Inventor

Lawrence S. Melvin, Jr.

Inventor
Ledyard, CT, US

Overview

69→
Patents
1978–2021
Patent span
Chemistry
Primary field (CPC C)

Patents· 69 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary
C07DHeterocyclic compounds36%
C07CAcyclic or carbocyclic compounds22%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations17%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium9%
A61KPreparations for medical, dental or toiletry purposes7%
C07BGeneral methods of organic chemistry5%
A61MDevices for introducing media into, or onto, the body1%
Y02PClimate change mitigation technologies in the production or processing of goods1%
C12CBeer1%
Y10TTechnical subjects covered by former us classification1%
PatentTitleYear
11,123,289Rapamycin for the treatment of lymphangioleiomyomatosis2021RE048711Apoptosis signal-regulating kinase inhibitors202111,103,449Inhalable rapamycin formulation for treating age-related conditions202110,307,371Rapamycin for the treatment of lymphangioleiomyomatosis201910,307,370Rapamycin for the treatment of lymphangioleiomyomatosis20199,586,932'Apoptosis signal-regulating kinase inhibitors'20179,067,933'Apoptosis signal-regulating kinase inhibitors'20158,598,360'Apoptosis signal-regulating kinase inhibitors'20138,552,196'Apoptosis signal-regulating kinase inhibitors'20138,378,108'Apoptosis signal-regulating kinase inhibitors'20138,217,155'Metabolites and derivatives of ambrisentan'20128,198,299'Cycloalkylidene and heterocycloalkylidene inhibitor compounds'20128,124,764'Fused heterocyclyc inhibitor compounds'20128,088,771'Cycloalkylidene and heterocycloalkylidene inhibitor compounds'20126,166,031'Substituted tetralins, chromans and related compounds in the treatment of asthma'20005,998,451'Substituted tetralins, chromans and related compounds in the treatment and related compounds in the treatment of asthma, arthritis and related diseases'19995,952,326'Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases'19995,698,550'Tetralin and chroman derivatives useful in the treatment of asthma, arthritis and related diseases'19975,550,152'Benzopyran and related LTB.sub.4 antagonists'19965,384,318'Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases'19955,298,512'Substituted chromans and their use in the treatment of asthma, arthritis and related diseases'19945,248,685'Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma'19935,059,609'Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases'19914,933,475'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19904,921,994'Pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes and derivatives thereof'19904,920,221'Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines'19904,870,084'Bicyclic benzo fused pyran compounds used for nausea treatment and prevention'19894,863,934'Bicyclic benzo fused pyran compounds used for producing analgesia'19894,835,192'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19894,831,059'Producing analgesia with pharmacologically active 2-hydroxy-4-(substituted) phenyl cycloalkanes derivatives'19894,739,079'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19884,695,571'Tricyclic oxindole antiinflammatory agents'19874,686,224'Oxindole antiinflammatory agents'19874,680,404'Benzopyrans'19874,644,005'Oxindole antiinflammatory agents'19874,642,373'Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents'19874,593,131'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19864,576,964'Substituted hexahydrobenzo[e]indene and octahydrophenanthrene CNS agents and pharmaceutical compositions thereof'19864,529,732'2-[2-hydroxy-4-(substituted)phenyl]piperidines'19854,486,428'Bicyclic benzo fused compounds'19844,486,609'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19844,476,131'Substituted hexahydropyrrolo[1,2-a]-quinolines, hexahydro-1H-pyrido[1,2-a]- q'19844,473,704'Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents'19844,454,144'Substituted dibenzo[b,d]pyran analgesics'19844,391,827'3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor'19834,387,229'3-[2-Hydroxy-4-(substituted)phenyl]azacycloalkanols and derivatives thereof'19834,379,783'Trialkylsilicon-containing phenylcycloalkane analgesics'19834,371,720'2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives'19834,341,906'1,9-Dihydroxyoctahydrophenanthrenes'19824,332,942'3-(2-Hydroxy-4-(substituted)phenyl)azacycloalkanes as analgesics'19824,331,602'Pharmacologically active 4-[2-hydroxy-4-(substituted]phenyl)naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19824,310,529'Intermediates to 1,9-dihydroxyoctahydrophenanthrenes'19824,310,669'Intermediates to 1,9-dihydroxyoctahydrophenanthrenes'19824,310,668'Intermediates to 1,9-dihydroxyoctahydrophenanthrenes'19824,306,097'3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents'19814,285,867'Pharmacologically active 4-[2-hydroxy-4-(substituted)phenyl]naphthalen-2(1H)-ones and 2-ols, derivatives thereof and intermediates therefor'19814,284,829'Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives'19814,283,569'Hydroxyalkyl and oxoalkyl substituted phenols as analgesics and sedatives'19814,270,005'1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor'19814,268,692'1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor'19814,268,523'1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor'19814,263,438'3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics'19814,237,133'1,9-Dihydroxyoctahydrophenanthrenes'19804,235,913'9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans'19804,188,495'1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor'19804,176,196'Hypoglycemic arylcyclohexane acetic acids'19794,165,323'9-Hydroxyhexahydrodibenzo[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans and intermediates therefor'19794,147,872'3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor'19794,118,559'9-Hydroxyhexahydrodibenzo[O,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo[b,d]pyrans and intermediates therefor'1978

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1978–2000Patents assigned to PFIZER (55)· patent assignee history
1978–1983Based in Gales Ferry, CT, US· patent location history
1981–2000Based in Ledyard, CT, US· patent location history
1990Based in Groton, CT, US· patent location history
2012–2021Patents assigned to GILEAD SCIENCES INC (9)· patent assignee history
2012–2013Patents assigned to MELVIN JR LAWRENCE S (7)· patent assignee history
2012–2013Patents assigned to GRAUPE MICHAEL (6)· patent assignee history
2012–2021Based in Longmont, CO, US· patent location history
2019–2021Patents assigned to AI THERAPEUTICS INC (4)· patent assignee history
2019–2021Based in Niwot, CO, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
PFIZER551978–2000
GILEAD SCIENCES INC92012–2021
MELVIN JR LAWRENCE Sself72012–2013
GRAUPE MICHAEL62012–2013
AI THERAPEUTICS INC42019–2021
Locations
LocationPatentsSpan
Ledyard, CT, US401981–2000
Gales Ferry, CT, US141978–1983
Longmont, CO, US102012–2021
Niwot, CO, US42019–2021
Groton, CT, US11990