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Inventor

Samuel P. McManus

Inventor
Huntsville, AL, US

Overview

85→
Patents
1995–2021
Patent span
Chemistry
Primary field (CPC C)

Patents· 85 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

A61Kprimary
A61KPreparations for medical, dental or toiletry purposes26%
C08GMacromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds22%
C08LCompositions of macromolecular compounds13%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations11%
C07DHeterocyclic compounds8%
C07CAcyclic or carbocyclic compounds6%
C07KPeptides4%
C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients3%
C07BGeneral methods of organic chemistry2%
C08FMacromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds2%
PatentTitleYear
10,941,248Methods for preparing functionalized polymers from polymer alcohols202110,759,906Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method202010,695,435Composition comprising a polymeric reagent202010,646,578Polymer derivatives having particular atom arrangements202010,421,838Methods for preparing polymeric reagents and compositions of polymeric reagents201910,220,020Polymer-des-ethyl sunitinib conjugates201910,144,804Method for preparing functionalized polymers from polymer alcohols201810,130,720Composition comprising a polymeric reagent201810,098,865Multi-arm polymeric prodrug conjugates of taxane-based compounds201810,039,737Multi-arm polymeric alkanoate conjugates20189,913,913'Method for preparing a polymeric reagent'20189,908,970'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20189,775,911'Composition comprising a polymeric reagent'20179,732,189'Methods for preparing polymeric reagents and compositions of polymeric reagents'20179,579,392'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20179,504,755'Multi-arm polymeric alkanoate conjugates'20169,433,684'Conjugates of small-interfering nucleic acids'20169,399,070'Compositions comprising a polymeric reagent and a pharmacologically active agent'20169,381,254'Methods for preparing polymeric reagents'20169,333,267'Thiol-selective water-soluble polymer derivatives'20169,334,364'Methods for preparing polymeric reagents and compositions of polymeric reagents'20169,308,273'Polymer derivatives comprising an acetal or ketal branching point'20169,308,274'Stabilized polymeric thiol reagents'20169,228,053'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20169,226,969'Salt form of a multi-arm polymer-drug conjugate'20169,220,790'Multi-arm polymeric alkanoate conjugates'20159,199,954'Non-ring hydroxy substituted taxanes and methods for synthesizing the same'20159,173,947'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20159,173,951'Carbohydrate-based drug delivery polymers and conjugates thereof'20159,089,610'Complexes of small-interfering nucleic acids'20159,090,740'Methods for preparing polymeric reagents'20159,085,659'Polymer derivatives comprising an imide branching point'20159,044,516'Pharmaceutical compositions of conjugates formed from polymer derivatives having particular atom arrangements'20159,040,658'Thiol-selective water-soluble polymer derivatives'20158,962,566'Multi-arm polymeric alkanoate conjugates'20158,916,693'Monoconjugated chitosans as delivery agents for small interfering nucleic acids'20148,911,718'Methods for preparing polymeric reagents'20148,905,235'Polymeric reagents comprising a terminal vinylic group and conjugates formed therefrom'20148,901,246'Method for preparing branched functionalized polymers using branched polyol cores'20148,895,759'Intermediates useful in the preparation of maleimide functionalized polymers'20148,865,149'Polymeric reagents comprising a ketone or a related functional group'20148,835,556'Hydrolytically stable maleimide-terminated polymers'20148,835,599'Segmented degradable polymers and conjugates made therefrom'20148,815,227'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20148,809,489'Methods for preparing polymeric reagents and compositions of polymeric reagents'20148,765,883'Stabilized polymeric thiol reagents'20148,722,032'Thiol-selective water-soluble polymer derivatives'20148,703,115'Methods for preparing conjugates'20148,680,263'Carbohydrate-based drug delivery polymers and conjugates thereof'20148,653,286'Intermediates useful in the preparation of maleimide functionalized polymers'20148,637,466'Multi-arm polymeric alkanoate conjugates'20148,633,277'Methods for forming polymer-drug conjugates'20148,604,159'Method for preparing functionalized polymers from polymer alcohols'20138,575,102'Conjugates having a releasable linkage'20138,568,705'Method for preparing branched functionalized polymers using branched polyol cores'20138,562,965'Polymer derivatives comprising an acetal or ketal branching point'20138,492,503'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20138,492,488'Stabilized polymeric thiol reagents'20138,461,295'Methods for preparing polymeric reagents and compositions of polymeric reagents'20138,440,787'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20138,435,505'Pharmaceutical compositions and methods for delivering such compositions'20138,309,680'Segmented degradable polymers and conjugates made therefrom'20128,304,511'Maleamic acid polymer derivatives and their bioconjugates'20128,268,948'Polymeric reagents comprising a terminal vinylic group and conjugates formed therefrom'20128,258,324'Intermediates useful in the preparation of maleimide functionalized polymers'20128,252,275'Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates'20128,227,555'Hydrolytically stable maleimide-terminated polymers'20128,217,123'Stabilized polymeric thiol reagents'20128,193,306'Methods for preparing polymeric reagents and compositions of polymeric reagents'20128,106,131'Hydrolytically stable maleimide-terminated polymers'20128,039,579'Intermediates useful in the preparation of maleimide functionalized polymers'20117,994,272'Maleamic acid polymer derivatives and their bioconjugates'20117,947,261'Conjugates formed from polymer derivatives having particular atom arrangements'20117,910,661'Thiol-selective water-soluble polymer derivatives'20117,887,789'Polymer derivatives having particular atom arrangements'20117,851,565'Stabilized polymeric thiol reagents'20107,790,835'Method of preparing maleimide functionalized polymers'20107,767,784'Methods for preparing polymeric reagents and compositions of polymeric reagents'20107,659,361'Maleamic acid polymer derivatives and their bioconjugates'20107,608,663'Method of preparing propionic acid-terminated polymers'20097,432,331'Hydrolytically stable maleimide-terminated polymers'20087,432,330'Hydrolytically stable maleimide-terminated polymers'20087,329,721'Maleamic acid polymer derivatives and their bioconjugates'20087,208,145'Polymeric reagents comprising a ketone or a related functional group'20075,451,433'Preparation of polymeric diacetylene thin films for nonlinear optical applications'1995

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1995–2021Based in Huntsville, AL, US· patent location history
2007–2008Based in Brevard, NC, US· patent location history
2009–2021Patents assigned to NEKTAR THERAPEUTICS (80)· patent assignee history
2012–2019Patents assigned to MCMANUS SAMUEL P (32)· patent assignee history
2012–2019Patents assigned to KOZLOWSKI ANTONI (27)· patent assignee history
2012–2019Patents assigned to CULBERTSON SEAN M (8)· patent assignee history
2012–2019Patents assigned to SHEN XIAOMING (7)· patent assignee history
2014–2020Based in Guntersville, AL, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
NEKTAR THERAPEUTICS802009–2021
MCMANUS SAMUEL Pself322012–2019
KOZLOWSKI ANTONI272012–2019
CULBERTSON SEAN M82012–2019
SHEN XIAOMING72012–2019
Locations
LocationPatentsSpan
Huntsville, AL, US431995–2021
Guntersville, AL, US382014–2020
Brevard, NC, US42007–2008