LexDanaLexDanabeta
Inventor

Timothy A. Springer

Inventor
Newton, MA, US

Overview

46→
Patents
1984–2021
Patent span
Human necessities
Primary field (CPC A)

Patents· 46 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Kprimary
C07KPeptides30%
A61KPreparations for medical, dental or toiletry purposes28%
G01NInvestigating or analysing materials by determining their chemical or physical properties11%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations10%
Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests9%
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms5%
G16CComputational chemistry1%
A61MDevices for introducing media into, or onto, the body1%
G06FElectric digital data processing1%
G06QInformation and communication technology [ict] specially adapted for administrative, commercial, financial, managerial or supervisory purposes1%
PatentTitleYear
11,104,713Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof202111,011,020Gaming system and method providing virtual currency with variable exchange rates and usage fees202110,273,283Modified integrin polypeptides, modified integrin polypeptide dimers, and uses thereof20199,580,482'Conformation-stabilized TRAP antigens'20178,877,893'Stabilized low affinity conformation of integrins for drug discovery'20148,247,185'Conformation specific antibodies'20128,241,627'Modified polypeptides stabilized in a desired conformation and methods for producing same'20128,021,668'Integrin alpha L I domain mutants with increased binding affinity'20117,968,284'Modified polypeptides stabilized in a desired conformation and methods for producing same'20117,927,591'Conformation specific antibodies'20117,879,577'Modified polypeptides stabilized in a desired conformation and methods for producing same'20117,674,604'Modified polypeptides stabilized in a desired conformation and methods for producing same'20107,354,588'Functional derivatives of ICAM-1 with altered ability to bind LFA-1 or HRV'20087,241,869'Modified polypeptides stabilized in a desired conformation and methods for producing same'20077,160,541'Modified polypeptides stabilized in a desired conformation and methods for producing same'20076,951,927'Proteins with integrin-like activity'20056,797,270'Functional derivatives of the intercellular adhesion molecule ICAM-1 in anti-viral therapy'20046,777,191'Use of functional derivatives of the intercellular adhesion molecule ICAM-1 in diagnosis of viral infection'20046,683,158'Alpha-subunit of the Mac-1 leukocyte adhesion receptor'20046,511,664'Intercellular adhesion molecule2 and its binding ligands'20036,436,403'Pharmaceutical composition of the intercellular adhesion molecule ICAM-1 for use in anti-viral prophylactic therapy'20026,358,510'ICAM-1 derivatives with altered ability to bind LFA-1'20026,030,947'Methods of treating p150,95-mediated inflammation and ICAM-1-mediated viral infection'20005,948,758'Methods for treating various disease states by reducing adhesion of leukocytes of target cells'19995,891,841'Methods of using intercellular adhesion molecule-3 (ICAM-3), antibodies thereto, and soluble fragments thereof'19995,877,295'Antibodies which bind a subpopulation of Mac-1 (CD11b/CD18) molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen'19995,849,896'.alpha.-subunit of the Mac-1 leukocyte adhesion receptor'19985,831,036'Soluble fragments of human intercellular adhesion molecule-1'19985,739,032'Cloning LFA-1'19985,686,265'Leukocyte adhesion receptors'19975,629,162'Method of identifying agents which modulate ICAM-3 binding to LFA-1'19975,612,216'Nucleotide sequence encoding intercellular adhesion molecule-1 and fragments thereof'19975,599,676'Method for isolating a novel receptor for .alpha.4 integrins'19975,565,550'Antibodies to ICAM-2, and fragments thereof'19965,514,555'Assays and therapeutic methods based on lymphocyte chemoattractants'19965,512,660'Purified ICAM-2 and fragment thereof'19965,489,533'Isolated nucleic acid molecules encoding ICAM-2'19965,475,091'R6-5-D6, an antibody which binds intercellular adhesion molecule-1'19955,460,945'Device and method for analysis of blood components and identifying inhibitors and promoters of the inflammatory response'19955,395,929'Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor'19955,288,854'Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1'19945,284,931'Intercellular adhesion molecules, and their binding ligands'19945,190,859'Purification of LFA-3'19935,071,964'Protein micelles'19914,956,281'DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3'19904,427,653'Method of making monoclonal antibodies'1984

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1990–2008Patents assigned to DANA FARBER CANCER INST INC (20)· patent assignee history
1990–2021Based in Newton, MA, US· patent location history
1991–2014Based in Chestnut Hill, MA, US· patent location history
1994–2012Patents assigned to BLOOD RES CENTER (16)· patent assignee history
1995Based in Newtown, MA, US· patent location history
2012–2014Patents assigned to SPRINGER TIMOTHY A (3)· patent assignee history
2012Patents assigned to SHIMAOKA MOTOMU (2)· patent assignee history
2017Based in Boston, MA, US· patent location history
2019–2021Patents assigned to CHILDRENS MEDICAL CT CORP (2)· patent assignee history
2021Based in Reno, NV, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
DANA FARBER CANCER INST INC201990–2008
BLOOD RES CENTER161994–2012
SPRINGER TIMOTHY Aself32012–2014
CHILDRENS MEDICAL CT CORP22019–2021
SHIMAOKA MOTOMU22012
Locations
LocationPatentsSpan
Newton, Massachusetts, US301990–2021
Chestnut Hill, Massachusetts, US121991–2014
Reno, NV, US12021
Boston, Massachusetts, US12017
Newtown, Massachusetts, US11995