Inventor

Laszlo J. Szarka

Inventor

East Brunswick, NJ, US

Overview

1980–2003

Patent span

Chemistry

Primary field (CPC C)

Patents· 34 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C12Pprimary

C12PFermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture33%

C07DHeterocyclic compounds15%

Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests13%

C12NMicroorganisms or enzymes11%

C12RIndexing scheme associated with subclasses c12c - c12q, relating to microorganisms6%

C07CAcyclic or carbocyclic compounds4%

C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms4%

G01NInvestigating or analysing materials by determining their chemical or physical properties4%

C07BGeneral methods of organic chemistry3%

A61KPreparations for medical, dental or toiletry purposes2%

PatentTitleYear

6,515,170'Enzymatic oxidative deamination process'2003 6,468,781'Stereoselective reductive amination of ketones'2002 6,261,810'Enzymatic oxidative deamination process'2001 6,140,088'Stereoselective reductive amination of ketones'2000 H0001893'Enzymatic reduction method for the preparation of halohydrins'2000 6,043,064'Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof'2000 5,986,095'Enantioselective preparation of halophenyl alcohols and acylates'1999 H0001817'Enzymatic methods for the preparation of pradimicins'1999 5,811,292'Lipase esterification processes for resolution of enantiomeric mixtures of intermediates in the preparation of taxanes'1998 5,739,016'Enzymatic hydrolysis method for the preparation of C-13 hydroxyl-bearing taxanes, and use thereof in the preparation of C-13 acyloxy-bearing taxanes'1998 5,700,669'Enzymatic hydrolysis method for the conversion of C-7 sugar to C-7 hydroxyl taxanes'1997 5,686,298'Enzymatic reduction method for the preparation of compounds useful for preparing taxanes'1997 H0001679'Process for preparing an optically pure intermediate for a phosphonosulfonate soualene synthetase inhibitor'1997 5,620,876'Enzymatic hydrolysis and esterification processes for the preparation of HMG-CoA reductase inhibitors and intermediates thereof'1997 5,567,614'Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes'1996 5,559,017'Microbial reduction of benzazepines and benzothiazepine derivatives'1996 5,523,219'Enzymatic hydrolysis method for the preparation of C-10 hydroxyl-bearing taxanes and enzymatic esterification method for the preparation of C-10 acyloxy-bearing'1996 5,516,676'Preparation of C-13 hydroxyl-bearing taxanes using nocardioides or a hydrolase isolated therefrom'1996 5,478,734'Method of chiral epoxidation of benzopyran or pyranopyridine derivatives using microorganisms'1995 5,420,337'Enzymatic reduction method for the preparation of compounds useful for preparing taxanes'1995 5,420,037'Process for separation of enantiomeric 3-mercapto-2-substituted alkanoic acid using lipase P30 and synthesis of captopril type compounds'1995 5,413,935'Process for selecting an enantiomer of a hydroxy lactone using pseudomonas lipase'1995 5,393,663'Stereoselective preparation of halophenyl alcohols from ketones'1995 5,391,495'Stereoselective reduction of ketones'1995 5,324,662'Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters'1994 5,266,710'(Exo,exo)-7-oxabicyclo[2.2.1]heptane-2,3-dimethanol; monoacyl ester and diacyl ester'1993 5,177,006'Enzymatic resolution process'1993 5,128,263'Enzymatic resolution process hydrolyzing thio-ester'1992 5,106,736'Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds'1992 5,084,387'Microbiological hydrolysis for the preparation of (exo,exo)-7-oxabicyclo(2.2.1) heptane-2,3, monoacyl ester dimethanol'1992 4,981,794'Method of preparing D(-)-.beta.-hydroxyisobutyric acid by fermentation'1991 4,748,117'Method for forming amphotericin B crystals in fermentation broth'1988 4,250,258'Use of phenoxyalkanes as precursors in penicillin V fermentation'1981 4,208,481'Use of phenylalkanes as precursors in benzylpenicillin fermentation'1980

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1980–1999Patents assigned to SQUIBB & SONS INC (19)· patent assignee history

1980–2003Based in East Brunswick, NJ, US· patent location history

1993Patents assigned to KRONENTHAL DAVID (1)· patent assignee history

1993Patents assigned to PATEL RAMESH N (1)· patent assignee history

1993Patents assigned to SZARKA LASZLO J (1)· patent assignee history

1995–2003Patents assigned to BRISTOL MYERS SQUIBB CO (14)· patent assignee history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
SQUIBB & SONS INC	19	1980–1999
BRISTOL MYERS SQUIBB CO	14	1995–2003
KRONENTHAL DAVID	1	1993
PATEL RAMESH N	1	1993
SZARKA LASZLO Jself	1	1993

Locations

Location	Patents	Span
East Brunswick, New Jersey, US	34	1980–2003