Inventor

James E. Bradner

Inventor

Weston, MA, US

Overview

44→

Patents

2012–2021

Patent span

Human necessities

Primary field (CPC A)

Patents· 44 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

A61Kprimary

A61KPreparations for medical, dental or toiletry purposes27%

C07DHeterocyclic compounds27%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations24%

Y02ATechnologies for adaptation to climate change7%

C07JSteroids4%

C12NMicroorganisms or enzymes4%

G01NInvestigating or analysing materials by determining their chemical or physical properties2%

C07KPeptides1%

C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms1%

C07BGeneral methods of organic chemistry1%

PatentTitleYear

10,980,808Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies2021 10,934,256Compounds and methods for treating cancer2021 10,925,868Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use2021 10,913,752Bivalent bromodomain inhibitors and uses thereof2021 10,899,768Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use2021 10,881,668Acetamide thienotriazolodiazepines and uses thereof2021 10,813,939Bromodomain inhibitor as adjuvant in cancer immunotherapy2020 10,793,571Uses of diazepane derivatives2020 10,730,860Diaminopyrimidine benzenesulfone derivatives and uses thereof2020 10,676,484Compositions and methods for treating leukemia2020 10,676,504Method for preparing largazole analogs and uses thereof2020 10,669,253Methods to induce targeted protein degradation through bifunctional molecules2020 10,633,371EZH2 inhibitors and uses thereof2020 10,538,534Synthesis and utility of new capgroup largazole analogs2020 10,525,139Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use2020 10,464,925Methods to induce targeted protein degradation through bifunctional molecules2019 10,464,897Compounds and methods for treating cancer2019 10,407,441Compositions and methods for treating neoplasia, inflammatory disease and other disorders2019 10,308,653Diazepane derivatives and uses thereof2019 10,239,888Targeted protein degradation using a mutant E3 ubiquitin ligase2019 10,150,756Diaminopyrimidine benzenesulfone derivatives and uses thereof2018 10,125,114Methods to induce targeted protein degradation through bifunctional molecules2018 9,975,896Inhibitors of transcription factors and uses thereof2018 9,951,074Dihydropteridinone derivatives and uses thereof2018 9,821,068'Methods to induce targeted protein degradation through bifunctional molecules'2017 9,815,849'Compositions and methods for treating leukemia'2017 9,789,120'Male contraceptive compositions and methods of use'2017 9,770,512'Methods to induce targeted protein degradation through bifunctional molecules'2017 9,763,956'Diagnostic and treatment methods in subjects having or at risk of developing resistance to cancer therapy'2017 9,750,816'Methods to induce targeted protein degradation through bifunctional molecules'2017 9,714,946'Bromodomain binding reagents and uses thereof'2017 9,695,172'Diazepane derivatives and uses thereof'2017 9,694,084'Methods to induce targeted protein degradation through bifunctional molecules'2017 9,535,067'DOT1L probes'2017 9,506,060'LNA antisense oligonucleotides for the modulation of Myc expression'2016 9,458,165'DOT1L inhibitors'2016 9,320,741'Compositions and methods for treating neoplasia, inflammatory disease and other disorders'2016 9,301,962'Male contraceptive compositions and methods of use'2016 9,186,402'Method for preparing largazole analogs and uses thereof'2015 9,074,009'Stabilized MAML peptides and uses thereof'2015 8,981,083'Compositions and methods for treating neoplasia, inflammatory disease and other disorders'2015 8,623,853'Treatment of cancers characterized by chromosomal rearrangement of the NUT gene'2014 8,513,290'Method for preparing largazole analogs and uses thereof'2013 8,217,076'Method for preparing largazole analogs and uses thereof'2012

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

2012–2021Patents assigned to DANA FARBER CANCER INST INC (44)· patent assignee history

2012–2020Patents assigned to UNIV COLORADO STATE RES FOUND (5)· patent assignee history

2012–2013Patents assigned to BOWERS ALBERT (2)· patent assignee history

2012–2020Based in Cambridge, MA, US· patent location history

2013–2020Patents assigned to UNIV NOTRE DAME DU LAC (4)· patent assignee history

2015–2021Based in Weston, MA, US· patent location history

2016–2017Patents assigned to BAYLOR COLLEGE MEDICINE (2)· patent assignee history

2016Based in Boston, MA, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
DANA FARBER CANCER INST INC	44	2012–2021
UNIV COLORADO STATE RES FOUND	5	2012–2020
UNIV NOTRE DAME DU LAC	4	2013–2020
BAYLOR COLLEGE MEDICINE	2	2016–2017
BOWERS ALBERT	2	2012–2013

Locations

Location	Patents	Span
Weston, Massachusetts, US	36	2015–2021
Cambridge, Massachusetts, US	7	2012–2020
Boston, Massachusetts, US	1	2016