Inventor

William F. Hoffman

Inventor

Lansdale, PA, US

Overview

1978–2008

Patent span

Chemistry

Primary field (CPC C)

Patents· 59 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary

C07DHeterocyclic compounds54%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations23%

C07CAcyclic or carbocyclic compounds9%

A61KPreparations for medical, dental or toiletry purposes7%

C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium5%

C07HSugars2%

C07KPeptides1%

PatentTitleYear

7,378,411'Substituted thienopyrimidinones as a mitotic kinesin inhibitor'2008 7,348,440'Mitotic kinesin inhibitors'2008 7,329,762'Prodrugs of mitotic kinesin inhibitors'2008 7,262,187'Substituted oxazolo- and thizaolopyrimidinones as a mitotic kinesin inhibitor'2007 7,262,186'Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor'2007 7,186,723'Tyrosine kinase inhibitors'2007 7,109,204'Tyrosine kinase inhibitors'2006 7,060,705'Mitotic kinesin inhibitors'2006 6,794,393'Tyrosine kinase inhibitors'2004 6,306,874'Tyrosine kinase inhibitors'2001 6,228,871'Angiogenesis inhibitors'2001 6,211,184'Integrin antagonists'2001 5,981,546'Integrin antagonists'1999 5,972,975'Substituted 2-aminopyridines as inhibitors of nitric oxide synthase'1999 5,929,120'Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption'1999 5,925,655'.alpha..sub.v .beta..sub.3 antagonists'1999 5,919,792'Integrin antagonists'1999 5,786,373'Fibrinogen receptor antagonists'1998 5,741,796'Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption'1998 5,648,368'Fibrinogen receptor antagonists'1997 5,559,127'Fibrinogen receptor antagonists'1996 5,455,243'Fibrinogen receptor antagonists for inhibiting aggregation of blood platelets'1995 5,281,585'Fibrinogen receptor antagonists for inhibiting aggregation of blood platelets'1994 5,053,525'Oxo-analogs of mevinolin-like antihyper-cholesterolemic agents'1991 5,049,696'Antihypercholesterolemic compounds'1991 4,937,264'Antihypercholesterolemic compounds'1990 4,937,263'Antihypercholesterolemic compounds'1990 4,916,162'Antihypercholesterolemic compounds'1990 4,894,466'Intermediates and processes for .beta.-6-hydroxymethyl HMG-CoA reductable inhibitors'1990 4,894,465'Intermediates and processes for 6-hydroxymethyl HMG-CoA reductable inhibitors'1990 4,876,366'Antihypercholesterolemic compounds'1989 4,876,279'Antihypercholesterolemic compounds'1989 4,866,090'Novel HMG-CoA reductase inhibitors'1989 4,864,038'Antihypercholesterolemic compounds'1989 4,857,547'Novel HMG-CoA reductase inhibitors'1989 4,855,456'Intermediates for 6-alpha-hydroxymethyl HMG-CoA reductase inhibitors'1989 4,851,436'HMG-CoA reductase inhibitors'1989 4,847,306'Antihypercholesterolemic compounds'1989 4,841,074'Intermediates and processes for 6-carboxy HMG-CoA reductase inhibitors'1989 4,771,071'Antihypercholesterolemic compounds'1988 4,766,145'Antihypercholesterolemic compounds'1988 4,710,513'Substituted pyranone inhibitors of cholesterol synthesis'1987 4,668,699'Novel HMG-CoA reductase inhibitors'1987 4,665,091'Macrocyclic lactone HMG-CoA reductase inhibitors'1987 4,661,483'Antihypercholesterolemic lactone compounds, compositions and use'1987 4,567,289'Substituted pyranone inhibitors of cholesterol synthesis'1986 4,503,072'Antihypercholesterolemic compounds'1985 4,472,426'Antihypercholesterolemic compounds'1984 4,459,422'Substituted pyranone inhibitors of cholesterol synthesis'1984 4,450,171'Antihypercholesterolemic compounds'1984 4,444,784'Antihypercholesterolemic compounds'1984 4,375,475'Substituted pyranone inhibitors of cholesterol synthesis'1983 4,322,563'Substituted biphenyl-2-carboxaldehydes'1982 4,237,130'2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids'1980 4,237,144'2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans'1980 4,189,496'2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid'1980 4,154,742'Certain 5-substituted or unsubstituted phenyl or furyl benzofuran 2-carboxylic acids'1979 4,100,294'5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives'1978 4,085,117'6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids'1978

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1978–2008Patents assigned to MERCK & CO INC (59)· patent assignee history

1978–2008Based in Lansdale, PA, US· patent location history

1978–1979Based in Chalfont, PA, US· patent location history

1999Based in Rahway, NJ, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
MERCK & CO INC	59	1978–2008

Locations

Location	Patents	Span
Lansdale, Pennsylvania, US	56	1978–2008
Chalfont, Pennsylvania, US	2	1978–1979
Rahway, New Jersey, US	1	1999