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Inventor

Arthur F. Kluge

Inventor
Lincoln, MA, US

Overview

79→
Patents
1977–2021
Patent span
Chemistry
Primary field (CPC C)

Patents· 79 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary
C07DHeterocyclic compounds28%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations26%
A61KPreparations for medical, dental or toiletry purposes18%
C12NMicroorganisms or enzymes5%
C07CAcyclic or carbocyclic compounds4%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium4%
C07KPeptides3%
C07BGeneral methods of organic chemistry3%
C12YEnzymes3%
C07HSugars2%
PatentTitleYear
11,117,889IRAK degraders and uses thereof202111,034,670Poly-ADP ribose polymerase (PARP) inhibitors202110,968,172USP30 inhibitors202110,906,885PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof202110,874,743IRAK degraders and uses thereof202010,828,300Substituted 2,4-diaminopyrimidines as kinase inhibitors202010,766,888HMOX1 inducers202010,662,195Protein kinase conjugates and inhibitors202010,611,790Nicotinamide riboside and nicotinamide mononucleotide derivatives for use in the treatments of mitochondrial-related diseases202010,596,1722,4-disubstituted pyrimidines useful as kinase inhibitors202010,550,071PPAR agonists202010,479,775PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof201910,399,958PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof201910,266,609Immunomodulating beta-1,6-D-glucans201910,188,627PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof201910,010,5482,4-disubstituted pyrimidines useful as kinase inhibitors20189,987,276Substituted 2,4-diaminopyrimidines as kinase inhibitors20189,938,234PPAR agonists20189,694,086'HCV protease inhibitors and uses thereof'20179,676,785'HCV protease inhibitors and uses thereof'20179,556,426'Protein kinase conjugates and inhibitors'20179,409,921'2,4-disubstituted pyrimidines as kinase inhibitors'20169,393,246'4,6-disubstituted pyrimidines as kinase inhibitors'20169,296,704'Substituted pyrimidines as protein kinase inhibitors'20169,296,737'Substituted 2,4-diaminopyrimidines as kinase inhibitors'20169,212,181'Substituted 2,4-diaminopyrimidines as kinase inhibitors'20159,163,061'HCV protease inhibitors and uses thereof'20159,067,929'Heterocyclic compounds and uses thereof'20159,040,541'4,6-disubstituted pyrimidines useful as kinase inhibitors'20158,778,877'HCV protease inhibitors and uses thereof'20148,748,606'4,6-diaminopyrimidines useful as kinase inhibitors'20148,741,837'HCV protease inhibitors and uses thereof'20148,710,222'2,4-disubstituted pyrimidines useful as kinase inhibitors'20148,609,679'2,4-diaminopyrimidines useful as kinase inhibitors'20138,586,600'Heterocyclic compounds and uses thereof'20138,518,958'Pyrido [2,3-D] pyrimidines and their use as kinase inhibitors'20138,450,335'2,4-disubstituted pyrimidines useful as kinase inhibitors'20138,450,348'Derivatives of squaric acid with anti-proliferative activity'20138,445,498'4,6-disubstituted pyrimidines useful as kinase inhibitors'20138,338,439'2,4-disubstituted pyrimidines useful as kinase inhibitors'20128,329,901'4,6-disubstitued pyrimidines useful as kinase inhibitors'20128,309,685'HCV protease inhibitors and uses thereof'20128,304,418'Pyrazolopyrimidinone kinase inhibitor'20128,293,705'HCV protease inhibitors and uses thereof'20128,242,271'Heterocyclic compounds and uses thereof'20128,232,283'Raf inhibitors'20128,097,619'Inhibitors of cyclin-dependent kinases, compositions and uses related thereto'20127,989,465'4,6-disubstituted pyrimidines useful as kinase inhibitors'20117,982,036'4,6-disubstitued pyrimidines useful as kinase inhibitors'20117,893,057'Inhibitors of cyclin-dependent kinases, compositions and uses related thereto'20117,786,112'Inhibitors of cyclin-dependent kinases, compositions and uses related thereto'20107,605,175'Inhibitors of cyclin-dependent kinases, compositions and uses related thereto'20096,753,329'Inhibitors of cyclin-dependent kinases, compositions and uses related thereto'20046,423,519'Compositions and methods for inhibiting fungal growth'20025,824,657'Aminoacyl sulfamides for the treatment of hyperproliferative disorders'19985,049,497'Novel process for the synthesis of the enantiomers of bicyclo(4.2.0)oct-2-en-7-one and derivatives'19914,678,805'Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties'19874,608,388'Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties'19864,567,264'Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry'19864,558,129'Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and .beta.-blockade'19854,499,100'Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and .beta.-blockade'19854,497,818'2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antihypertensives and platelet aggregation inhibitors'19854,436,914'Benzodioxane-imidazoline compounds as antihypertensives'19844,431,665'Acylated laidlomycin derivatives'19844,410,534'3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors'19834,405,622'[1-(1,4-Benzodioxan-2-yl)-4-(4-aminopyrimidin-2-yl]piperazines useful as anti-depressants'19834,349,549'Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s'19824,315,021'2-(1,4-Benzodioxan-2-ylalkyl)imidazoles'19824,302,469'2-(1,4-Benzodioxan-2-ylalkyl)imidazoles useful as antidepressants'19814,301,171'2-(1,4-Benzodioxan-2-ylalkyl)benzimidazoles useful as anti-depressants'19814,255,432'8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof'19814,244,961'1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents'19814,232,038'5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids'19804,174,399'Treatment of lactic acidosis in ruminants'19794,097,579'5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo›1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof'19784,089,969'5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof'19784,087,539'5-(2-Furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- and 5-(3-thenoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof'19784,051,150'3-(2-Dialkylamino-2-dialkylphosphonylvinyl)-6,11-dihydrodibe nzo-[b.e.]-thiepin-11-one'19774,046,801'13-Cis prostaglandin derivatives'1977

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1977–1991Patents assigned to SYNTEX INC (23)· patent assignee history
1977–1991Based in Los Altos, CA, US· patent location history
1977–1984Based in Palo Alto, CA, US· patent location history
1984–2015Patents assigned to KLUGE ARTHUR F (17)· patent assignee history
1998–2021Based in Lincoln, MA, US· patent location history
2012–2020Patents assigned to CELGENE AVILOMICS RES INC (21)· patent assignee history
2012–2017Patents assigned to SINGH JUSWINDER (12)· patent assignee history
2018–2021Patents assigned to MITOBRIDGE INC (10)· patent assignee history
2020Based in Concord, MA, US· patent location history
2021Based in Gainesville, FL, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
SYNTEX INC231977–1991
CELGENE AVILOMICS RES INC212012–2020
KLUGE ARTHUR Fself171984–2015
SINGH JUSWINDER122012–2017
MITOBRIDGE INC102018–2021
Locations
LocationPatentsSpan
Lincoln, Massachusetts, US531998–2021
Los Altos, California, US221977–1991
Palo Alto, California, US21977–1984
Gainesville, Florida, US12021
Concord, Massachusetts, US12020