Inventor
John N. Freskos
Inventor
Clayton, MO, US
Overview
Patents· 128 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Dprimary
C07DHeterocyclic compounds22%
A61KPreparations for medical, dental or toiletry purposes21%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations20%
C07CAcyclic or carbocyclic compounds19%
C07KPeptides14%
C04BLime, magnesia1%
C07BGeneral methods of organic chemistry1%
Y02ATechnologies for adaptation to climate change1%
A61MDevices for introducing media into, or onto, the body0%
C07HSugars0%
PatentTitleYear
9,662,387'Functional, cross-linked nanostructures for tandem optical imaging and therapy'20179,295,650'Functional, cross-linked nanostructures for tandem optical imaging and therapy'20168,871,189'MMP-targeted therapeutic and/or diagnostic nanocarriers'20148,628,751'Pyrazine derivatives for optical imaging and therapy'20148,481,734'Pyrazine derivatives and uses thereof, including in medical imaging and visualization applications'2013RE043802'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'2012RE043596'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'2012RE042889'α- and β- amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20117,902,195'Pyridine [3,4-b] pyrazinones'20117,829,564'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20107,727,997'N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives'20107,531,538'α- and β-Amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20097,339,078'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20087,320,983'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20087,312,333'Retroviral protease inhibitors'20077,297,793'Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors'20077,294,642'1,3-Diamino-2-hydroxypropane pro-drug derivatives'20077,214,715'Compounds to treat Alzheimer\'s disease'20077,176,242'N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives'20077,161,033'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20077,144,897'Hydroxy alkyl amines'20067,141,609'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20067,141,594'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20067,119,203'Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors'20067,115,618'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20067,115,632'Sulfonyl aryl or heteroaryl hydroxamic acid compounds'20067,098,202'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20067,091,219'Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors'20067,045,518'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'20067,038,084'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20067,026,485'Retroviral protease inhibitors'20066,924,286'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20056,890,937'Aromatic sulfone hydroxamic acid metalloprotease inhibitor'20056,890,928'Aromatic sulfone hydroxamic acids and their use as protease inhibitors'20056,861,539'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20056,846,954'α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20056,794,511'Sulfonyl aryl or heteroaryl hydroxamic acid compounds'20046,762,187'Retroviral protease inhibitors'20046,750,233'Aromatic sulfone hydroxamic acid metalloprotease inhibitor'20046,750,228'Aromatic sulfone hydroxamic acid metalloprotease inhibitor'20046,747,027'Thiol sulfonamide metalloprotease inhibitors'20046,743,929'Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20046,730,669'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20046,727,282'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20046,716,844'Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds'20046,696,449'Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors'20046,689,794'Aromatic sulfone hydroxamates and their use as protease inhibitors'20046,683,093'Aromatic sulfone hydroxamic acids and their use as protease inhibitors'20046,683,210'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20046,673,822'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20046,667,307'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'20036,656,954'Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds'20036,646,010'- and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20036,583,299'-amino--sulfonyl hydroxamic acid compounds'20036,569,882'Bis-sulfonamide hydroxyethyl-amino retroviral protease inhibitors'20036,541,489'Aromatic sulfone hydroxamic acid metalloprotease inhibitor'20036,534,493'- and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20036,506,759'Retroviral protease inhibitors'20036,500,832'- and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20026,476,027'N-hydroxy 4-sulfonyl butanamide compounds'20026,472,407' and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20026,469,207'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20026,458,785'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20026,455,581'-and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20026,417,387'-and -amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20026,407,134'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20026,388,132'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20026,384,036'Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors'20026,380,188'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'20026,380,258'Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds'20026,362,183'Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds'20026,335,460'-and -amino acid hydroxyethlamino sulfonamides useful as retroviral protease inhibitors'20026,316,496'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20016,313,345'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20016,310,080'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20016,248,775'.alpha.- and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20016,214,861'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20016,180,646'Retroviral protease inhibitors'20016,172,101'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20016,172,082'.alpha.- and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20016,169,085'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'20016,150,556'Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20006,147,117'Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20006,143,747'Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors'20006,143,788'Bis-amino acid hydroxyethlamino sulfonamide retroviral protease inhibitors'20006,087,359'Thioaryl sulfonamide hydroxamic acid compounds'20006,063,795'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'20006,060,476'.alpha.- and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20006,046,190'Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors'20006,022,994'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'20006,013,649'Thiol sulfone metalloprotease inhibitors'20005,985,870'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'19995,972,989'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'19995,968,970'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'19995,968,942'.alpha.- and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19995,965,588'Sulfonylalkanoylamino hydroxyethylamimo sulfonamides useful as retroviral protease inhibitors'19995,965,601'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'19995,948,790'Retroviral protease inhibitors'19995,843,946'.alpha.-and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,830,897'.alpha.- and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,786,483'.alpha.-and .beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,776,971'Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'19985,760,076'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,760,064'Sulfonylalkanoylamino hydroxyethylamino sulfanamides useful as retroviral protease inhibitors'19985,756,534'Retroviral protease inhibitors'19985,756,533'Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors'19985,753,660'Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'19985,744,481'.beta.-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,714,605'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19985,705,500'Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors'19985,703,076'Retroviral protease inhibitors'19975,698,569'Retroviral protease inhibitors'19975,648,364'Retroviral protease inhibitors'19975,643,924'Retroviral protease inhibitors'19975,639,769'Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19975,622,949'Retroviral protease inhibitors'19975,620,977'Retroviral protease inhibitors'19975,610,190'Retroviral protease inhibitors'19975,521,219'Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19965,510,388'Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19965,510,349'Retroviral protease inhibitors'19965,508,294'Sulfonylalkanoylamino hydroxyethlamino sulfonamides useful as retroviral protease inhibitors'19965,482,947'Retroviral protease inhibitors'19965,475,027'Retroviral protease inhibitors'19955,475,013'Retroviral protease inhibitors'19955,463,104'Succinoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors'19954,929,723'Process for preparing 2-deoxynucleosides'19904,914,233'Synthesis of beta-thymidine'1990Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1990Based in Baton Rouge, LA, US· patent location history
1995–2007Patents assigned to SEARLE & CO (82)· patent assignee history
1995–2004Patents assigned to MONSANTO CO (13)· patent assignee history
1995–2017Based in Clayton, MO, US· patent location history
2003–2007Patents assigned to PHARMACIA CORP (12)· patent assignee history
2006–2010Patents assigned to ELAN PHARM INC (4)· patent assignee history
2007–2012Patents assigned to SEARLE LLC (8)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| SEARLE & CO | 82 | 1995–2007 |
| MONSANTO CO | 13 | 1995–2004 |
| PHARMACIA CORP | 12 | 2003–2007 |
| SEARLE LLC | 8 | 2007–2012 |
| ELAN PHARM INC | 4 | 2006–2010 |
Locations
| Location | Patents | Span |
|---|---|---|
| Clayton, MO, US | 126 | 1995–2017 |
| Baton Rouge, LA, US | 2 | 1990 |