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Inventor

Roland E. Dolle

Inventor
King of Prussia, PA, US

Overview

84→
Patents
1995–2021
Patent span
Chemistry
Primary field (CPC C)

Patents· 84 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary
C07DHeterocyclic compounds28%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations21%
A61KPreparations for medical, dental or toiletry purposes14%
C07CAcyclic or carbocyclic compounds12%
C07KPeptides8%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium5%
Y02ATechnologies for adaptation to climate change5%
C07BGeneral methods of organic chemistry3%
C40BCombinatorial chemistry2%
C04BLime, magnesia0%
PatentTitleYear
11,124,598Method for producing a TEMPOL-containing urethane resin composition having an improved storage stability202110,654,883Inorganic salts of nicotinic acid mononucleotide as anti-aging agents20209,108,966'Beta-lactamase inhibitors'20158,969,570'Beta-lactamase inhibitors'20158,895,560'Opioid antagonists'20148,580,788'Opioid antagonists'20138,404,693'Substituted piperidine compounds and methods of their use'20138,288,546'Substituted piperidine compounds and methods of their use'20128,278,323'Opioid antagonists'20128,071,611'Spirocyclic heterocyclic derivatives and methods of their use'20118,022,060'Spirocyclic heterocyclic derivatives and methods of their use'20117,906,646'Spirocyclic heterocyclic derivatives and methods of their use'20117,884,102'Substituted piperidine compounds and methods of their use'20117,829,576'Beloxepin and analogs for the treatment of pain'20107,820,827'Substituted piperidine compounds and methods of their use'20107,767,814'Substituted piperidine compounds and methods of their use'20107,671,052'Phenyl derivatives and methods of use'20107,638,527'Spirocyclic heterocyclic derivatives and methods of their use'20097,598,261'Spirocyclic heterocyclic derivatives and methods of their use'20097,576,207'Spirocyclic heterocyclic derivatives and methods of their use'20097,563,802'Spirocyclic heterocyclic derivatives and methods of their use'20097,544,676'Sulfamoyl benzamides and methods of their use'20097,538,110'Opioid antagonists'20097,381,721'Substituted piperidine compounds'20087,338,962'Spirocyclic heterocyclic derivatives and methods of their use'20087,297,796'Sulfamoyl benzamide derivatives and methods of their use'20077,160,902'Amide derivatives and methods of their use'20077,091,354'Processes for the preparation of peripheral opioid antagonist compounds and intermediates thereto'20067,087,749'Substituted piperidine compounds and methods of their use'20067,037,916'Pyrimidine derivatives as IL-8 receptor antagonists'20067,034,051'Fused bicyclic carboxamide derivatives and methods of their use'20066,995,261'4-pyridazinecarboxamides and esters as interleukin-1β converting enzyme inhibitors'20066,992,090'Substituted piperidine compounds and methods of their use'20066,992,193'Sulfonylamino phenylacetamide derivatives and methods of their use'20066,919,347'Bradykinin B1 receptor antagonists'20056,900,213'Bisaryl derivatives having FSH modulatory activity'20056,887,865'N-heterocyclic derivatives as NOS inhibitors'20056,864,263'N-heterocyclic derivatives as NOS inhibitors'20056,864,368'N-heterocyclic derivatives as NOS inhibitors'20056,852,713'Lactam derivatives and methods of their use'20056,849,739'N-heterocyclic derivatives as NOS inhibitors'20056,846,829'N-heterocyclic derivatives as NOS inhibitors'20056,841,673'N-heterocyclic derivatives as nos inhibitors'20056,841,674'N-heterocyclic derivatives as NOS inhibitors'20056,794,510'Processes for the preparation of peripheral opioid antagonist compounds and intermediates thereto'20046,747,031'N-heterocyclic derivatives as NOS inhibitors'20046,670,473'N-heterocyclic derivatives as NOS inhibitors'20036,624,166'Pyridazines as interleukin-1 converting enzyme inhibitors'20036,576,614'Peptide analogs as irreversible interleukin-1 protease inhibitors'20036,432,933'Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases'20026,432,947'N-heterocyclic derivatives as NOS inhibitors'20026,407,080'N-(pyrimidinyl)-aspartic acid analogs as interleukin-1 converting enzyme inhibitors'20026,326,393'Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases'20016,265,228'Process for preparing combinatorial amide alcohol libraries'20016,255,120'Combinatorial library of substituted statine esters and amides via a novel acid-catalyzed rearrangement'20016,218,551'Combinatorial hydroxy-amino acid amide libraries'20016,191,277'Hydroxypropylamide peptidomimetics as inhibitors of aspartyl proteases'20016,175,020'Spirodiamino acid scaffold for combinatorial synthesis'20016,162,800'N-(pyrimidinyl)-aspartic acid analogs as interleukin-1.beta. converting enzyme inhibitors'20006,150,344'Hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases'20006,121,266'Pyridazines as interleukin-1.beta. converting enzyme inhibitors'20005,986,102'Hydroxypropylamide peptidomimetics as inhibitors of aspartyl proteases'19995,985,838'Peptide analogs as irreversible interleukin-1.beta. protease inhibitors'19995,976,894'Combinatorial amide alcohol libraries'19995,972,719'Combinatorial hydroxy-amino acid amide libraries'19995,962,506'Glycol and hydroxyphosphonate peptidomimetics as inhibitors of aspartyl proteases'19995,948,696'Combinatorial biaryl amino acid amide libraries'19995,892,038'Hydroxy-amino acid amides'19995,872,262'Hydroxy-amino acid amides'19995,843,905'Peptidic phosphinyloxymethyl ketones as interleukin-1.beta.-converting enzyme inhibitors'19985,834,514'Halomethyl amides as IL-1.beta. protease inhibitors'19985,734,054'Hydroxy-amino acid amides'19985,677,283'.alpha.-heteroaryloxymethyl ketones as interleukin - 1 .beta. converting enzyme inhibitors'19975,670,494'N-(pyrimidinyl)-aspartic acid analogs as interleukin-1.beta. converting enzyme inhibitors'19975,639,745'Fused-bicyclic lactams as interleukin-1.beta. converting enzyme inhibitors'19975,622,967'Quinolone carboxamide Calpain inhibitors'19975,585,357'Heteroaryloxymethyl ketones as interleukin-1.beta.converting enzyme inhibitors'19965,585,486'Peptidic ketones as interleukin-1.beta.-converting enzyme inhibitors'19965,578,601'Nonpeptide bradykinin antagonists'19965,565,430'Azaaspartic acid analogs as interleukin-1.beta. converting enzyme inhibitors'19965,552,400'Fused-bicyclic lactams as interleukin-1.beta. converting enzyme inhibitors'19965,510,380'Nonpeptide bradykinin antagonists'19965,462,939'Peptidic ketones as interleukin-1.beta.-converting enzyme inhibitors'19955,447,954'Phenylderivate as inhibitors of ATP citrate lyase'1995

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1995–2013Based in King of Prussia, PA, US· patent location history
1996–1997Based in Pottstown, PA, US· patent location history
1998–2005Patents assigned to PHARMACOPEIA INC (20)· patent assignee history
1998–2006Patents assigned to VERTEX PHARMA (9)· patent assignee history
2002–2005Patents assigned to BERLEX LAB (8)· patent assignee history
2004–2014Patents assigned to ADOLOR CORP (29)· patent assignee history
2005–2006Patents assigned to PHARMACOPEIA DRUG DISCOVERY (9)· patent assignee history
2013–2015Based in Hopkinton, MA, US· patent location history
2014–2015Based in Ashland, MA, US· patent location history
2021Based in Schwabmuenchen, DE· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
ADOLOR CORP292004–2014
PHARMACOPEIA INC201998–2005
PHARMACOPEIA DRUG DISCOVERY92005–2006
VERTEX PHARMA91998–2006
BERLEX LAB82002–2005
Locations
LocationPatentsSpan
King of Prussia, Pennsylvania, US761995–2013
Ashland, Massachusetts, US22014–2015
Hopkinton, Massachusetts, US22013–2015
Pottstown, Pennsylvania, US21996–1997
Schwabmuenchen, DE12021