Inventor
Mark Leo Michaels
Inventor
Encino, CA, US
Overview
Patents· 21 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Kprimary
C07KPeptides27%
A61KPreparations for medical, dental or toiletry purposes26%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations24%
C12NMicroorganisms or enzymes19%
C40BCombinatorial chemistry1%
G01NInvestigating or analysing materials by determining their chemical or physical properties1%
Y02ATechnologies for adaptation to climate change1%
PatentTitleYear
11,072,640Methods of treating non-alcoholic steatohepatitis using FGF21 mutants202110,308,704Isolated nucleic acid molecules encoding stabilized receptor polypeptides and uses thereof201910,189,890Variants of tissue inhibitor of metalloproteinase type three (TIMP-3), compositions and methods201910,011,642Methods of treating of diabetes and obesity using FGF21 mutants20189,708,375'Inhibitory polypeptides specific to WNT inhibitors'20179,688,756'Variant Fc-polypeptides with enhanced binding to the neonatal Fc receptor'20179,517,264'Human FGF receptor and β-Klotho binding proteins'20169,493,530'FGF21 mutants comprising a mutation at position 98, 171 and/or 180'20169,279,013'FGF-21 mutants comprising polyethylene glycol and uses thereof'20169,273,106'FGF mutants with reduced proteolysis and aggregation'20169,273,114'Stabilized receptor polypeptides and uses thereof'20168,835,385'FGF21 polypeptides comprising two or more mutations and uses thereof'20148,795,985'FGF 21 polypeptides comprising two or more mutations and uses thereof'20148,642,546'FGF21 mutant fusion polypeptides and uses thereof'20148,618,053'FGF21 mutants multimers and uses thereof'20138,410,043'Stabilized activin IIB receptor polypeptides and uses thereof'20138,410,051'FGF21 mutants and uses thereof'20138,361,963'Uses of FGF21 polypeptides comprising two or more mutations'20138,188,040'FGF21 mutants and uses thereof'20128,034,770'FGF21 polypeptides comprising two or more mutations'20116,096,865'Mutants of the green fluorescent protein having improved fluorescent properties at 37.degree.'2000Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
2000–2021Patents assigned to AMGEN INC (21)· patent assignee history
2000–2021Based in Encino, CA, US· patent location history
2012–2016Patents assigned to LI YUE-SHENG (9)· patent assignee history
2012–2016Patents assigned to MICHAELS MARK LEO (9)· patent assignee history
2012–2016Patents assigned to SUN JEONGHOON (9)· patent assignee history
2012–2016Patents assigned to XU JING (8)· patent assignee history
2016Based in Encinco, CA, US· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| AMGEN INC | 21 | 2000–2021 |
| LI YUE-SHENG | 9 | 2012–2016 |
| MICHAELS MARK LEOself | 9 | 2012–2016 |
| SUN JEONGHOON | 9 | 2012–2016 |
| XU JING | 8 | 2012–2016 |
Locations
| Location | Patents | Span |
|---|---|---|
| Encino, California, US | 20 | 2000–2021 |
| Encinco, California, US | 1 | 2016 |