Inventor
Jan M. A. van Deursen
Inventor
Rochester, MN, US
Overview
Patents· 14 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C12Nprimary
C12NMicroorganisms or enzymes25%
A61KPreparations for medical, dental or toiletry purposes23%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations19%
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms17%
A01KAnimal husbandry8%
C07KPeptides8%
PatentTitleYear
10,517,866Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor201910,478,432Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye201910,478,433Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss201910,413,542Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinase201910,328,073Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells201910,328,058Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques201910,258,618Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen201910,251,376Increasing healthy lifespan and delaying progression of age-related phenotypes by selectively removing senescent cells201910,010,546Treatment of ophthalmic conditions by selectively removing senescent cells from the eye20189,993,472Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM220189,980,962Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease20189,968,076Transgenic animals capable of being induced to delete senescent cells20187,220,892'Transgenic mouse lacking PAPP-A activity'20077,098,377'IEX-1 knockout animals'2006Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
2006–2007Patents assigned to MAYO FOUNDATION (2)· patent assignee history
2006–2019Based in Rochester, MN, US· patent location history
2018–2019Patents assigned to MAYO FOUND MEDICAL EDUCATION & RES (12)· patent assignee history
2018–2019Patents assigned to BUCK INST RES AGING (10)· patent assignee history
2018–2019Patents assigned to UNITY BIOTECHNOLOGY INC (10)· patent assignee history
2019Patents assigned to BUCK INSTITUTE FOR RES AGING (1)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| MAYO FOUND MEDICAL EDUCATION & RES | 12 | 2018–2019 |
| BUCK INST RES AGING | 10 | 2018–2019 |
| UNITY BIOTECHNOLOGY INC | 10 | 2018–2019 |
| MAYO FOUNDATION | 2 | 2006–2007 |
| BUCK INSTITUTE FOR RES AGING | 1 | 2019 |
Locations
| Location | Patents | Span |
|---|---|---|
| Rochester, Minnesota, US | 14 | 2006–2019 |