Inventor
Richard P. Rava
Inventor
Redwood City, CA, US
Overview
Patents· 70 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C12Qprimary
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms13%
B01JChemical or physical processes, e.g. catalysis or colloid chemistry10%
C40BCombinatorial chemistry9%
G01NInvestigating or analysing materials by determining their chemical or physical properties9%
G16BBioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or protein-related data processing in computational molecular biology8%
C07KPeptides6%
C07HSugars5%
C07BGeneral methods of organic chemistry5%
B82YSpecific uses or applications of nanostructures4%
B01LChemical or physical laboratory apparatus for general use4%
PatentTitleYear
11,130,995Simultaneous determination of aneuploidy and fetal fraction202111,072,814Using cell-free DNA fragment size to determine copy number variations202110,941,442Sequencing methods and compositions for prenatal diagnoses202110,837,055Non-invasive prenatal diagnosis of fetal genetic condition using cellular DNA and cell free DNA202010,741,269Method for improving the sensitivity of detection in determining copy number variations202010,718,020Methods of fetal abnormality detection202010,662,474Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing202010,658,070Resolving genome fractions using polymorphism counts202010,612,096Methods for determining fraction of fetal nucleic acids in maternal samples202010,586,610Detecting and classifying copy number variation202010,482,993Analyzing copy number variation in the detection of cancer201910,415,089Detecting and classifying copy number variation201910,400,267Generating cell-free DNA libraries directly from blood201910,388,403Analyzing copy number variation in the detection of cancer201910,119,167Non-invasive prenatal diagnosis of fetal genetic condition using cellular DNA and cell free DNA201810,095,831Using cell-free DNA fragment size to determine copy number variations201810,017,807Generating cell-free DNA libraries directly from blood20189,657,342'Sequencing methods for prenatal diagnoses'20179,493,828'Methods for determining fraction of fetal nucleic acids in maternal samples'20169,493,831'Methods of fetal abnormality detection'20169,447,453'Resolving genome fractions using polymorphism counts'20169,411,937'Detecting and classifying copy number variation'20169,323,888'Detecting and classifying copy number variation'20169,260,745'Detecting and classifying copy number variation'20169,115,401'Partition defined detection methods'20158,859,196'Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays'20148,700,341'Partition defined detection methods'20148,637,434'System for photolithographic synthesis of polymer arrays'20148,532,936'Normalizing chromosomes for the determination and verification of common and rare chromosomal aneuploidies'20138,318,430'Methods of fetal abnormality detection'20128,309,496'Methods for photolithographic synthesis of polymer arrays utilizing anti-reflective coatings'20128,067,578'Substrate preparation process'20117,790,389'Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays'20107,470,783'Photocleavable protecting groups and methods for their use'20086,881,836'Photocleavable protecting groups and methods for their use'20056,830,936'Integrated nucleic acid diagnostic device'20046,720,149'Methods for concurrently processing multiple biological chip assays'20046,706,875'Substrate preparation process'20046,697,665'Systems and methods of molecular spectroscopy to provide for the diagnosis of tissue'20046,690,966'Methods of molecular spectroscopy to provide for the diagnosis of tissue'20046,667,394'Printing oligonucleotide arrays'20036,566,515'Photocleavable protecting groups and methods for their use'20036,326,211'Method of manipulating a gas bubble in a microfluidic device'20016,309,831'Method of manufacturing biological chips'20016,307,042'Substrate preparation process'20016,294,327'Apparatus and method for detecting samples labeled with material having strong light scattering properties, using reflection mode light and diffuse scattering'20016,252,236'Method and apparatus for imaging a sample on a device'20016,239,273'Printing molecular library arrays'20016,197,595'Integrated nucleic acid diagnostic device'20016,168,948'Miniaturized genetic analysis systems and methods'20016,147,205'Photocleavable protecting groups and methods for their use'20006,056,926'Apparatus and method for parallel coupling reactions'20006,043,080'Integrated nucleic acid diagnostic device'20006,025,601'Method and apparatus for imaging a sample on a device'20005,959,098'Substrate preparation process'19995,922,591'Integrated nucleic acid diagnostic device'19995,874,219'Methods for concurrently processing multiple biological chip assays'19995,856,174'Integrated nucleic acid diagnostic device'19995,834,758'Method and apparatus for imaging a sample on a device'19985,831,070'Printing oligonucleotide arrays using deprotection agents solely in the vapor phase'19985,599,695'Printing molecular library arrays using deprotection agents solely in the vapor phase'19975,578,832'Method and apparatus for imaging a sample on a device'19965,562,100'Method for laser induced fluorescence of tissue'19965,545,531'Methods for making a device for concurrently processing multiple biological chip assays'19965,503,805'Apparatus and method for parallel coupling reactions'19965,452,723'Calibrated spectrographic imaging'19955,419,323'Method for laser induced fluorescence of tissue'19955,345,941'Contour mapping of spectral diagnostics'19945,312,396'Pulsed laser system for the surgical removal of tissue'19945,201,318'Contour mapping of spectral diagnostics'1993Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1993–2020Patents assigned to RAVA RICHARD P (15)· patent assignee history
1993–1996Based in Boston, MA, US· patent location history
1994–2004Patents assigned to MASSACHUSETTS INST TECHNOLOGY (7)· patent assignee history
1994–2004Based in Waltham, MA, US· patent location history
1995–2004Based in Palo Alto, CA, US· patent location history
1996–2014Patents assigned to AFFYMETRIX INC (30)· patent assignee history
1996–2008Based in San Jose, CA, US· patent location history
2000–2021Based in Redwood City, CA, US· patent location history
2012–2021Patents assigned to VERINATA HEALTH INC (26)· patent assignee history
2014–2019Patents assigned to RHEES BRIAN K (4)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| AFFYMETRIX INC | 30 | 1996–2014 |
| VERINATA HEALTH INC | 26 | 2012–2021 |
| RAVA RICHARD Pself | 15 | 1993–2020 |
| MASSACHUSETTS INST TECHNOLOGY | 7 | 1994–2004 |
| RHEES BRIAN K | 4 | 2014–2019 |
Locations
| Location | Patents | Span |
|---|---|---|
| Redwood City, California, US | 37 | 2000–2021 |
| San Jose, California, US | 15 | 1996–2008 |
| Palo Alto, California, US | 12 | 1995–2004 |
| Boston, Massachusetts, US | 3 | 1993–1996 |
| Waltham, Massachusetts, US | 2 | 1994–2004 |