Inventor
William Markland
Inventor
Milford, MA, US
Overview
Patents· 28 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Kprimary
C07KPeptides25%
A61KPreparations for medical, dental or toiletry purposes17%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations15%
C12NMicroorganisms or enzymes12%
C40BCombinatorial chemistry12%
C04BLime, magnesia7%
G01NInvestigating or analysing materials by determining their chemical or physical properties6%
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms2%
G16BBioinformatics, i.e. information and communication technology [ict] specially adapted for genetic or protein-related data processing in computational molecular biology2%
C07DHeterocyclic compounds1%
PatentTitleYear
11,110,108Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors20218,663,629'Kallikrein-binding “kunitz domain†proteins and analogues thereof'20148,431,359'Nucleic acids encoding polypeptide inhibitors of human plasmin derived from the Kunitz domains'20138,283,321'Kallikrein-binding “Kunitz domain†proteins and analogues thereof'20128,002,891'Crystallization of C-Jun N-Terminal Kinase 3 (JNK3)'20117,919,462'Inhibitors of human plasmin derived from the Kunitz domains'20117,893,007'Directed evolution of novel binding proteins'20117,736,867'Nucleic acids encoding polypeptide inhibitors of human plasmin derived from the Kunitz domains'20107,628,983'Kallikrein-binding “Kunitz domain†proteins and analogues thereof'20097,413,537'Directed evolution of disulfide-bonded micro-proteins'20087,383,135'Methods of designing inhibitors for JNK kinases'20087,256,094'Method for changing threshold voltage of device in resist asher'20077,208,293'Directed evolution of novel binding proteins'20077,118,879'Method of recovering a nucleic acid encoding a proteinaceous binding domain which binds a target material'20067,078,383'ITI-D1 Kunitz domain mutants as HNE inhibitors'20066,979,538'Directed evolution of novel binding proteins'20056,953,674'Inhibitors of human plasmin derived from the kunitz domains'20056,423,498'Variegated Kunitz domain peptide library and uses thereof'20026,333,402'Kallikrein-binding \"Kunitz domain\" proteins and analogues thereof'20016,103,499'Inhibitors of human plasmin derived from the Kunitz domains'20006,071,723'Inhibitors of human plasmin derived from the Kunitz domains'20006,057,287'Kallikrein-binding \"Kunitz domain\" proteins and analogues thereof'20006,010,880'Inhibitors of human plasmin derived from the kunitz domains'20005,837,500'Directed evolution of novel binding proteins'19985,663,143'Engineered human-derived kunitz domains that inhibit human neutrophil elastase'19975,571,698'Directed evolution of novel binding proteins'19965,403,484'Viruses expressing chimeric binding proteins'19955,223,409'Directed evolution of novel binding proteins'1993Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1993–1996Patents assigned to PROTEIN ENG CORP (3)· patent assignee history
1993–2011Based in Milford, MA, US· patent location history
1997–2014Patents assigned to DYAX CORP (20)· patent assignee history
2007Based in Colorado Springs, CO, US· patent location history
2008–2021Patents assigned to VERTEX PHARMA (3)· patent assignee history
2008–2014Based in Southborough, MA, US· patent location history
2012–2014Patents assigned to LADNER ROBERT C (3)· patent assignee history
2012–2014Patents assigned to MARKLAND WILLIAM (3)· patent assignee history
2021Based in Boston, MA, US· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| DYAX CORP | 20 | 1997–2014 |
| LADNER ROBERT C | 3 | 2012–2014 |
| MARKLAND WILLIAMself | 3 | 2012–2014 |
| PROTEIN ENG CORP | 3 | 1993–1996 |
| VERTEX PHARMA | 3 | 2008–2021 |
Locations
| Location | Patents | Span |
|---|---|---|
| Milford, Massachusetts, US | 18 | 1993–2011 |
| Southborough, Massachusetts, US | 8 | 2008–2014 |
| Boston, Massachusetts, US | 1 | 2021 |
| Colorado Springs, CO, US | 1 | 2007 |