Inventor
Craig A. Coburn
Inventor
Royersford, PA, US
Overview
Patents· 59 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Dprimary
C07DHeterocyclic compounds34%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations28%
A61KPreparations for medical, dental or toiletry purposes15%
C07CAcyclic or carbocyclic compounds7%
C07KPeptides4%
C07BGeneral methods of organic chemistry2%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium2%
C07HSugars2%
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms1%
G01NInvestigating or analysing materials by determining their chemical or physical properties1%
PatentTitleYear
11,053,243Inhibitors of hepatitis C virus replication202110,906,881Inhibitors of arginine gingipain202110,745,377Piperidine or piperazine linked imidazole and triazole derivatives and methods of use202010,738,062Chromane-substituted tetracyclic compounds and uses thereof for the treatment of viral diseases202010,676,470Inhibitors of lysine gingipain202010,646,494Heterocycle-substituted tetracyclic compounds and methods of use thereof for the treatment of viral diseases202010,519,131Benzazepine compounds, conjugates, and uses thereof201910,442,790Benzazepine compounds, conjugates, and uses thereof201910,428,045Benzazepine compounds, conjugates, and uses thereof201910,301,301Inhibitors of lysine gingipain201910,292,968Substituted heterocycles as bromodomain inhibitors201910,239,862Benzazepine compounds, conjugates, and uses thereof20199,988,375Inhibitors of lysine gingipain20189,981,969Imidazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug20189,975,888Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug20189,828,365Fused tetracyclic heterocyclic compounds and methods of use thereof for the treatment of viral diseases20179,758,473'Inhibitors of lysine gingipain'20179,556,202'Sulfonamide derivatives and methods of use thereof for improving the pharmacokinetics of a drug'20179,504,690'Tetracyclic xanthene derivatives and methods of use thereof for the treatment of viral diseases'20169,505,739'Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer\'s disease'20169,254,292'Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases'20169,139,569'Fused tricyclic aryl compounds useful for the treatment of viral diseases'20159,090,661'Inhibitors of hepatitis C virus replication'20158,933,040'Selective glycosidase inhibitors and uses thereof'20158,927,507'Selective glycosidase inhibitors and uses thereof'20158,871,759'Inhibitors of hepatitis C virus replication'20148,865,701'Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer\'S disease'20148,497,383'HIV protease inhibitors'20138,492,387'2-aminoimidazole beta-secretase inhibitors for the treatment of alzheimer\'s disease'20138,211,904'Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer\'s disease'20128,114,887'Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of alzheimer\'s disease'20127,968,571'2,4,6-substituted pyridyl derivative compounds useful as beta-secretase inhibitors for the treatment of Alzheimer\'s Disease'20117,932,275'2-aminopyridine compounds useful as β-secretase inhibitors for the treatment of alzheimer\'s disease'20117,847,100'1,3,5-substituted phenyl derivative compounds useful as beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20107,820,674'Aminomethyl beta-secretase inhibitors for the treatment of alzheimer\'s disease'20107,714,021'Pyrrolidin-3-yl compounds useful as beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20107,550,481'Phenylamide and pyridylamide beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20097,449,599'Phenyl carboxamide compounds useful as beta-secretase inhibitors for the treatment of alzheimer\'s disease'20087,371,853'Macrocyclic β-secretase inhibitors for the treatment of Alzheimer\'s disease'20087,348,356'Phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20087,329,746'Macrocyclic beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20087,291,620'N-alkyl phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20077,109,217'Phenylcarboxamide beta-secretase inhibitors for the treatment of Alzheimer\'s disease'20066,610,692'Thrombin inhibitors'20036,610,701'Thrombin inhibitors'20036,455,532'Pyrazinone thrombin inhibitors'20026,350,745'Thrombin inhibitors'20026,239,132'Thrombin inhibitors'20016,133,297'Thrombin inhibitors'20006,087,373'Thrombin inhibitors'20006,017,934'Thrombin inhibitors'20006,004,976'Thrombin inhibitors'19995,872,138'Thrombin inhibitors'19995,869,487'Pyrido›3,4-B!pyrazines for use as thrombin inhibitors'19995,846,978'HIV protease inhibitors useful for the treatment of AIDS'19985,798,377'Thrombin inhibitors'19985,747,540'HIV protease inhibitors useful for the treatment of AIDS'19985,541,327'Preparation of camptothecin analogs'19965,391,745'Methods of preparation of camptothecin analogs'1995Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1998–2009Patents assigned to MERCK & CO INC (21)· patent assignee history
1998–2003Based in Skippack, PA, US· patent location history
2000–2017Based in Royersford, PA, US· patent location history
2010–2021Patents assigned to MERCK SHARP & DOHME (23)· patent assignee history
2012–2020Patents assigned to COBURN CRAIG A (12)· patent assignee history
2014–2015Patents assigned to LIU KUN (4)· patent assignee history
2015–2021Based in San Rafael, CA, US· patent location history
2017–2021Patents assigned to CORTEXYME INC (5)· patent assignee history
2017–2021Based in Novato, CA, US· patent location history
2019–2020Based in Seattle, WA, US· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| MERCK SHARP & DOHME | 23 | 2010–2021 |
| MERCK & CO INC | 21 | 1998–2009 |
| COBURN CRAIG Aself | 12 | 2012–2020 |
| CORTEXYME INC | 5 | 2017–2021 |
| LIU KUN | 4 | 2014–2015 |
Locations
| Location | Patents | Span |
|---|---|---|
| Royersford, Pennsylvania, US | 28 | 2000–2017 |
| Skippack, Pennsylvania, US | 9 | 1998–2003 |
| San Rafael, California, US | 7 | 2015–2021 |
| Seattle, Washington, US | 6 | 2019–2020 |
| Novato, California, US | 5 | 2017–2021 |