Inventor

Joseph T. Klein

Inventor

Bridgewater, NJ, US

Overview

1981–2011

Patent span

Chemistry

Primary field (CPC C)

Patents· 89 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary

C07DHeterocyclic compounds62%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations30%

C07CAcyclic or carbocyclic compounds4%

A61KPreparations for medical, dental or toiletry purposes3%

C07HSugars1%

PatentTitleYear

7,994,168'Hexahydro-pyrazino[1,2-A]pyrimidine-4,7-dione derivatives substituted with amino acids'2011 7,919,508'3-piperidinylisochroman-5-ols as dopamine agonists'2011 7,652,007'Nitrogen-substituted hexahydropyrazino[1,2-A]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments'2010 7,169,925'Indole derivatives as interleukin-4 gene expression inhibitors'2007 6,022,880'Substituted pyridylamino indoles'2000 5,856,335'Substituted aminothienopyridines, pharmaceutical composition and use'1999 5,631,270'Substituted pyridinylamino-1H-indoles, 1H-indazoles, 2H-indazoles, benzo [b ]'1997 5,519,032'Substituted aminothienopyridines, pharmaceutical composition and use'1996 5,424,322'A personality disorder treatment method and composition'1995 5,405,856'Certain nitro-3-pyrinamines and 3-oxy-analogues'1995 5,328,918'Substituted pyridinylamino 1H-indazoles'1994 5,328,920'Substituted (pyridinylamino)-indoles'1994 5,296,488'Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory'1994 5,268,468'N-nitrosophenoxybenzenepropanamine and N-1-chloroethyl carbamate intermediates'1993 5,252,581'Substituted aminothienopyridines, pharmaceutical composition and use'1993 5,246,947'Substituted pyridinylamino-1,2-benzisothiazoles and their use for treating depression'1993 5,229,417'2-(3-phenylpropyl)hydrazines and method of treating personality disorders'1993 5,229,401'Substituted pyridinylamino benzo[b]thiophene compounds'1993 5,221,682'Heteroarylamino- and heteroaryloxypyridinamines and related compounds'1993 5,202,319'Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines'1993 5,194,618'N-(pyrrol-1-yl)pyridinamines'1993 5,185,350'Substituted pyridinylamino-1H-indoles,1H-indazoles,2H-indazoles, benzo (B)thiophenes and 1,2-benzisothiazoles'1993 5,179,099'2,3-dihydro-1-(pyridinylamino)-indoles'1993 5,179,204'N-substituted-4-pyrimidinamines and pyrimidinediamines'1993 5,177,088'Substituted 3-(pyridinylamino)-indoles'1993 5,166,163'3-(1H-indazol-3-yl)-4-pyridinamines'1992 5,155,098'N-heteroaryl-purin-6-amines, and pharmaceutical compositions and methods employing them'1992 5,102,891'1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates'1992 5,095,019'4-substituted dihydropyrido(4,3-D)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders'1992 5,059,602'4-substituted dihydropyrido(4,3-d)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders'1991 5,059,688'1-aryloxy-2,3,4,5-tetrahydro-3-benzazepine preparation'1991 5,055,476'3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives'1991 5,051,430'3-(1H-indazol-3-yl)-4-pyridinamines'1991 5,039,811'Preparation of N-(pyridinyl)-1H-indol-1-amines'1991 5,039,687'N-(pyrrol-1-yl)pyridinamine compounds having enhancing activity'1991 5,037,835'Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders'1991 5,034,403'Heteroarylamino-and heteroaryloxypyridinamines and related compounds'1991 5,032,599'N-(pyrrol-l-yl)pyridinamines'1991 5,017,578'N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents'1991 4,992,448'Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders'1991 4,988,690'1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof'1991 4,983,615'Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders'1991 4,983,608'N-substituted-4-pyrimidinamines and pyrimidinediamines'1991 4,970,218'N-(pyridinyl)-1H-indol-1-amines'1990 4,970,219'Heteroarylamino- and heteroaryloxypyridinamine compounds which have useful utility in treating skin disorders'1990 4,959,377'Phenoxypyridinamine compounds which are use as a dermatological composition'1990 4,959,378'Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders'1990 4,940,704'Pyrido[3,4-b][1,4]benzoxazepines'1990 4,935,418'Medical compositions of 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and use thereof'1990 4,931,457'Naphthylamino-and naphthyloxy-pyridinamine comounds useful as topical antiinflammatory agents for the treatment of skin disorders'1990 4,916,135'N-heteroaryl-4-quinolinamines'1990 4,900,742'N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties'1990 4,883,794'Pyrrolo(1,2-b)cinnolines'1989 4,880,822'N-(pyridinyl)-1H-indol-1-amines'1989 4,868,190'N-pyridinyl-9H-carbazol-9-amines'1989 4,806,554'Pyrazol and indazolpyridinamines'1989 4,800,203'Pyrrolo(1,2-b)cinnolines'1989 4,794,181'1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines'1988 4,792,562'N-(pyrrol-1-yl)pyridinamines having memory enhancing activity'1988 4,789,678'Memory enhancing .alpha.-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds'1988 4,752,610'N-(pyrrol-1-yl)pyridinamines having memory enhancing properties'1988 4,610,988'1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain'1986 4,609,658'1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure'1986 4,604,395'1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines'1986 4,598,152'6-fluoro-3-[3-(oxoheterocyclo)propyl]-1,2-benzisoxazoles'1986 4,591,586'6-fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles for treatment of pain, hypertension and psychoses'1986 4,588,727'Intermediates for pyrrolo[1,2-b][1,2,5]triazepines'1986 4,578,394'Cholinergic function increasing 3-[N-(pyridyl) carbamoyl]-1,4-dihydropyridines'1986 4,551,474'Methods of alleviating convulsions and pain employing 4-aryloxy-1,2,3,4 tetrahydroisoquinolines'1985 4,546,105'Pyrrolylaminopiperidines, compositions thereof and methods of use'1985 4,536,578'1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines'1985 4,524,209'6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles'1985 4,517,195'Pyrrolo[1,2-b][1,2,5]triazepines and pharmaceutical compositions thereof'1985 4,477,670'4-Aryloxy-1,2,3,4-tetrahydroisoquinolines'1984 4,458,075'6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles'1984 4,452,803'Pyrrolylaminopiperidines'1984 4,418,067'8-[3-(6-Fluoro-1,2-be nzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]dec.5)decan-4-one to treat pain'1983 4,416,887'1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxyl-4-phenylpiperidin es to treat pain'1983 4,415,581'1-[3-6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-pheny lpiperidines to treat psychoses'1983 4,410,699'Substituted 1,2,3,4-tetrahydro-4-isoquinolinols'1983 4,409,230'Pharmaceutical compositions and methods employing 8-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro-[4 .]decan-4-one and derivatives thereof'1983 4,396,770'1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy -4-phenylpiperidines'1983 4,390,544'{1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl} p'1983 4,375,471'4-Aryloxy-1,2,3,4-tetrahydroisoquinolines'1983 4,374,137'Spiro[benzofuranisoquinoline]s and their use as pharmaceuticals'1983 4,374,245'8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]- 1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one'1983 4,329,464'Spiro[dihydrobenzofuran-piperidines and -pyrrolidines]'1982 4,321,385'[(Aryl-1-pyrryl) methyl]-piperidinols and pyrrolidinols'1982 4,268,515'Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof'1981

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1981–1995Patents assigned to HOECHST ROUSSEL PHARMA (81)· patent assignee history

1981–2000Based in Bridgewater, NJ, US· patent location history

1983–1986Based in Somerville, NJ, US· patent location history

1996–2000Patents assigned to HOECHST MARION ROUSSEL INC (4)· patent assignee history

2007–2011Patents assigned to AVENTIS PHARMA INC (2)· patent assignee history

2007–2011Based in Neshanic Station, NJ, US· patent location history

2010–2011Patents assigned to SANOFI AVENTIS DEUTSCHLAND (2)· patent assignee history

2011Based in Neshanic, NJ, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
HOECHST ROUSSEL PHARMA	81	1981–1995
HOECHST MARION ROUSSEL INC	4	1996–2000
AVENTIS PHARMA INC	2	2007–2011
SANOFI AVENTIS DEUTSCHLAND	2	2010–2011

Locations

Location	Patents	Span
Bridgewater, New Jersey, US	70	1981–2000
Somerville, New Jersey, US	15	1983–1986
Neshanic Station, New Jersey, US	3	2007–2011
Neshanic, New Jersey, US	1	2011