Inventor
Helmut Buschmann
Inventor
Aachen, DE
Overview
Patents· 76 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Pprimary
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations33%
C07DHeterocyclic compounds26%
C07CAcyclic or carbocyclic compounds19%
A61KPreparations for medical, dental or toiletry purposes14%
C07BGeneral methods of organic chemistry6%
B01JChemical or physical processes, e.g. catalysis or colloid chemistry1%
C04BLime, magnesia1%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium1%
C12PFermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture1%
PatentTitleYear
10,624,896Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy202010,149,852Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy20189,914,705'1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing analgesic effect of opioids and attenuating the dependency thereof'20189,850,198Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds20179,827,244Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease20179,505,758'Substituted 1,5-naphthyridines as endonuclease inhibitors'20169,434,745'7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease'20169,393,220'Co-crystals of tramadol and NSAIDs'20169,388,119'Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds'20169,359,351'Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease'20169,199,987'Substituted naphthyridines for the treatment, amelioration or prevention of a viral disease'20159,084,774'Co-crystals of duloxetine and cox-inhibitors for the treatment of pain'20159,045,486'Pyrimidone derivatives and their use in the treatment, amelioration or prevention of a viral disease'20159,018,222'Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy'20158,952,039'Pyridone derivatives and their use in the treatment, ameloriation or prevention of a viral disease'20158,921,388'Dihydroxypyrimidine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease'20148,877,974'Process for the preparation of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropy1)-phenol'20148,877,753'1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing analgesic effect of opioids and attenuating the dependency thereof'20148,791,300'Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis'20148,669,399'Process for preparing substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds'20148,501,802'Co-crystals of duloxetine and COX-INHIBITORs for the treatment of pain'20138,309,610'Crystalline forms of (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)cyclohexane-1,3-diol hydrochloride'20128,236,845'Heterocyclyl-substituted-tetrahydro-naphthalen-amine derivatives, their preparation and use as medicaments'20128,207,156'Substituted pyrazoline compounds, their preparation and use as medicaments'20128,168,679'Salts of Tramadol and Naproxen and their crystal forms in the treatment of pain'20128,097,641'Heterocyclyl substituted tetrahydronaphthalene derivatives as 5-HT7 receptor ligands'20128,044,053'Sulfonamide substituted pyrazoline compounds, their preparation and use as CB1 modulators'20117,994,364'Crystalline forms of (−)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride'20117,897,589'Substituted pyrazoline compounds, their preparation and use as medicaments'20117,888,510'2-′4(phenylamino)-piperidin-1-yl!-n-phenyl-acetamine derivatives and related compounds as neuropeptide Y5 (NPY5) ligands for the treatment of obesity'20117,816,358'Pharmaceutical formulations comprising N,N′-disubstituted piperazine compounds'20107,790,898'Substituted 3-phenylpiperidine compounds, their preparation and use'20107,763,754'Process for producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol'20107,649,114'Separation of stereoisomeric N,N-dialkylamino-2alkyl-3-hydroxy-3-phenylalkanes'20107,569,585'1, 5-diaminopentan-3-ol compounds and related treatment methods'20097,550,624'Pharmaceutically active salts and esters of 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol and 3- (3-dimethylamino-1-ethyl-1-hydroxy-2-methylpropyl)-phenol and methods of using same'20097,507,816'Pharmaceutical preparations comprising substituted beta-aminoalcohols'20097,417,170'Process for the preparation of substituted 3-aryl-butylamine compounds'20087,390,812'N, N\'-disubstituted piperazine compounds and their use as analgesics'20087,320,980'Substituted pyrido(1,2-a)pyrimidines and their use as NOS inhibitors'20087,273,952'Substituted C-cyclohexylmethylamine derivatives'20077,271,192'Substituted 2-pyrrolidine-2-yl-1H-indole compounds'20077,235,693'Process for chlorinating tertiary alcohols'20077,230,018'Substituted propane-1,3-diamine derivatives and the pharmaceutical use thereof'20077,217,729'Substituted indoles, process for the production thereof and use thereof for combatting pain'20077,211,585'5-HT7 receptor antagonists'20077,211,584'5-HT7 receptor ligands'2007RE039593'1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects'2007RE039530'3-amino-3-arylpropan-1-ol-compounds, their preparation and use'20077,183,274'Piperidine-2,6-diones heterocyclically substituted in the 3-position'20077,168,937'Method for the enzymatic resolution of the racemates of aminomethyl-aryl-cyclohexanol derivatives'20077,109,349'Process for obtaining Cizolirtine and its enantiomers'20067,105,538'2-pyrrolidin-2-yl-[1,3,4]-oxadiazole compounds and their use as anti-depressants'20067,078,531'Process for obtaining enantiomers of thienylazolylalcoxyethanamines'20067,064,236'Substituted 1-aryl-but-3-enylamine and 1-aryl-but-2-enylamine compounds'20067,041,662'Substituted benzo [b] azepin-2-one compounds'20067,022,739'Substituted 1-aminobutan-3-ol compounds'20066,998,409'Substituted 2-pyridine cyclohexane-1,4-diamine compounds'20066,979,742'Process for obtaining enantiomers of thienylazolylalcoxyethanamines'20056,890,959'Aminomethyl-phenyl-cyclohexanone derivatives'20056,828,345'O-substituted 6-methyltramadol derivatives'20046,815,443'5-Amino-1-pentene-3-ol substituted derivatives'20046,710,080'Substituted 2-dialkylaminoalkylbiphenyl derivatives'20046,656,937'Substituted glutarimides and their use as inhibitors of IL-12 production'20036,653,508'3-amino-2-benzyl-1-phenylpropane derivatives'20036,476,044'Use of morphine derivatives as medicaments for the treatment of neuropathic problems'20026,410,790'3-amin3-arylpropan-1-ol compounds, their preparation and use'20026,344,558'1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect'20026,288,278'3-amino-3-arylpropan-1-ol-compounds, their preparation and use'2001RE037355'6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients'20016,248,737'1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects'20016,022,895'Substituted amino compounds and their use as substances having an analgesic effect'20005,811,582'Dimethyl-(3-aryl-but-3-enyl)-amine compounds as pharmaceutical active ingredients'19985,733,936'6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients'19985,728,885'Method of preparing the enantiomers of O-dimethyltramadol'19985,723,668'Method of separating the racemate of tramadol'1998Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1998–2017Patents assigned to GRUENENTHAL GMBH (45)· patent assignee history
1998–2018Based in Aachen, DE· patent location history
2005–2018Patents assigned to ESTEVE LABOR DR (17)· patent assignee history
2005–2020Based in Barcelona, ES· patent location history
2006–2011Based in Esplugues de Llobregat, ES· patent location history
2010–2014Based in Sant Just Desvern, ES· patent location history
2012–2015Patents assigned to BUSCHMANN HELMUT HEINRICH (7)· patent assignee history
2013–2016Based in Walheim, DE· patent location history
2014–2017Patents assigned to HOFFMANN LA ROCHE (8)· patent assignee history
2014–2017Patents assigned to SAVIRA PHARMACEUTICALS GMBH (8)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| GRUENENTHAL GMBH | 45 | 1998–2017 |
| ESTEVE LABOR DR | 17 | 2005–2018 |
| HOFFMANN LA ROCHE | 8 | 2014–2017 |
| SAVIRA PHARMACEUTICALS GMBH | 8 | 2014–2017 |
| BUSCHMANN HELMUT HEINRICHself | 7 | 2012–2015 |
Locations
| Location | Patents | Span |
|---|---|---|
| Aachen, DE | 38 | 1998–2018 |
| Esplugues de Llobregat, ES | 20 | 2006–2011 |
| Barcelona, ES | 12 | 2005–2020 |
| Sant Just Desvern, ES | 4 | 2010–2014 |
| Walheim, DE | 2 | 2013–2016 |