Inventor
Yi Zhu
Inventor
Rochester, MN, US
Overview
Patents· 16 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Kprimary
A61KPreparations for medical, dental or toiletry purposes26%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations26%
C12NMicroorganisms or enzymes23%
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms21%
C07JSteroids2%
C07KPeptides2%
G01NInvestigating or analysing materials by determining their chemical or physical properties2%
PatentTitleYear
10,808,005Ligand for orphan nuclear receptor Nur77 and uses thereof202010,717,783Bispecific tetravalent antibodies and methods of making and using thereof202010,517,866Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor201910,478,433Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss201910,478,432Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye201910,413,542Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinase201910,328,073Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells201910,328,058Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques201910,258,618Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen201910,213,426Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population201910,130,628Treatment of joint pain201810,010,546Treatment of ophthalmic conditions by selectively removing senescent cells from the eye20189,993,472Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM220189,980,962Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease20189,855,266'Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline'20189,849,128Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells2017Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
2017–2019Patents assigned to BUCK INST RES AGING (14)· patent assignee history
2017–2019Patents assigned to MAYO FOUND MEDICAL EDUCATION & RES (14)· patent assignee history
2017–2019Patents assigned to UNITY BIOTECHNOLOGY INC (14)· patent assignee history
2017–2018Patents assigned to UNIV JOHNS HOPKINS (4)· patent assignee history
2017–2019Based in Rochester, MN, US· patent location history
2019Patents assigned to BUCK INSTITUE FOR RES ON AGING (1)· patent assignee history
2020Based in Xiamen, CN· patent location history
2020Based in Chengdu, CN· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| BUCK INST RES AGING | 14 | 2017–2019 |
| MAYO FOUND MEDICAL EDUCATION & RES | 14 | 2017–2019 |
| UNITY BIOTECHNOLOGY INC | 14 | 2017–2019 |
| UNIV JOHNS HOPKINS | 4 | 2017–2018 |
| BUCK INSTITUE FOR RES ON AGING | 1 | 2019 |
Locations
| Location | Patents | Span |
|---|---|---|
| Rochester, Minnesota, US | 14 | 2017–2019 |
| Xiamen, CN | 1 | 2020 |
| Chengdu, CN | 1 | 2020 |