Inventor
Robert E. Manning
Inventor
St. Louis, MO, US
Overview
Patents· 69 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Dprimary
C07DHeterocyclic compounds45%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations19%
A61KPreparations for medical, dental or toiletry purposes12%
C07CAcyclic or carbocyclic compounds9%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium3%
C08GMacromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds3%
G01NInvestigating or analysing materials by determining their chemical or physical properties2%
H04BTransmission2%
B01DSeparation1%
C07KPeptides1%
PatentTitleYear
7,132,437'Renal-selective biphenylalkyl 1H-substituted-1,2,4-triazole angiotensin II antagonists for treatment of hypertension'20066,943,189'Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG CO-A reductase inhibitors'20056,858,636'1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders'20056,642,268'Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors'20036,630,497'1-phenyl imidazol-2-one biphenylmethyl compounds for treatment of circulatory disorders'20036,576,780'Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors'20036,492,397'N-arylheteroarylalkyl imidazol-2-one compounds for treatment of arteriosclerosis'20026,451,833'N-substituted (-imidazolyl-toluyl)pyrrole compounds for treatment of circulatory disorders'20026,420,417'Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors'20026,268,392'Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors'20016,207,708'Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors'20016,008,368'Pharmaceutical compositions for treatment of circulatory disorders using N-substituted (.alpha.-imidazolyl-toluyl) pyrrole aniotensin II antagonists'19995,981,511'Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors'19995,945,408'Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors'19995,861,420'N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders'19995,736,579'Substituted spiro compounds for the treatment of inflammation'19985,674,879'Compositions including and methods of using conformationally restricted angiotensin II antagonist'19975,646,183'Phenyl amidine alkanoic acids useful as platelet aggregation inhibitors'19975,643,906'Method of using N-arylheteroarylalkyl imidazol-2-one compounds for treatment of a glaucoma disorder'19975,612,355'Phenyl amidine lactones useful as platelet aggregation inhibitors'19975,563,154'Tetrahydro-quinolinyl/isoquinolinyl-terminal alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19965,504,106'Phenyl amidine alkanoic acids and lactones useful as platelet aggregation inhibitors'19965,484,937'N-substituted N-(.alpha.-triazolyl-toluyl)pyrrole compounds for treatment of circulatory disorders'19965,451,592'Method of using N-arylheteroarylalkyl 1-heteroaryl-imidazol-2-one compounds for treatment of a glaucoma disorder'19955,451,597'Treatment of circulatory disorders using n-substituted (.alpha.-imidazolyl-toluyl) pyrrole angiotensin II antagonists'19955,441,970'Use of N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders'19955,434,162'Quinolinyl/isoquinolinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,426,105'Conformationally restricted angiotensin II antagonists'19955,422,349'Morpholino-oxazinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,416,084'Benzo-fused thiomorpholinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,413,998'Benzo-fused thiazopinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,953'Oxazopinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,975'Thiazolidinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,950'Benzo-fused oxazocinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,954'Benzo-fused oxazopinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,961'Benzo-fused morpholinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,411,959'1,4-Thiomorpholino-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,925'Oxazobicyclo terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,913'Oxazocinyl/thiazocinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,921'Thiazetidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,924'Benzo-fused oxazobicyclo terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,922'Thiozopinyl terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19955,409,945'Benzyo-fused thiazolidinyl terminated alkylamino ethylnyl alanine amino diol compounds for treatment of hypertension'19955,393,790'Substituted spiro compounds for the treatment of inflammation'19955,373,017'Imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19945,302,610'Renal-selective biphenylmethyl imidazole angiotensin II antagonists for treatment of hypertension'19945,252,591'Pyridinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension'19935,238,952'N-substituted imidazol-2-one compounds for treatment of circulatory disorders'19935,217,985'Renal-selective biphenylalkyl 1H-substituted-1,2,4-triazole angiotensin II antagonists for treatment of hypertension'19935,187,271'N-substituted (.alpha.-imidazolyl-toluyl) pyrrole compounds for treatment of circulatory disorders'19935,175,180'N-substituted N-(alpha-triazolyl-toluyl)pyrrole compounds and use for treatment of circulatory disorders'19925,164,403'N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders'19925,106,834'Linear free-sulfhydryl-containing oligopeptide derivatives as antihypertensive agents'19925,087,634'N-substituted imidazol-2-one compounds for treatment of circulatory disorders'19924,923,874'Use of 8-azapurin-6-one derivatives for control of hypertension'19904,723,442'High-temperature, high-shear capillary viscometer'19884,658,636'High-temperature, high-shear capillary viscometer'19874,544,663'Indolamine derivatives as anti-fertility agents'19854,295,694'Interceptor plug'19814,225,442'Core spun filtration roving'19804,054,665'2-Amino-5-(trifluoromethylphenylalkyl)-1,3,4 thiadiazoles used in the treatment of insomnia and anxiety'19773,992,396'2-Amino-5-(substituted or unsubstituted phenylalkyl)-thiadiazoles'19763,982,020'Substituted benzylidene hydrazines for treating hyperglycemia, obesity and inflammation'19763,978,057'Substituted amino-hydrazinopyridazines'19763,974,283'N-substituted-4-T-butyl-1-pyridinethiocarboxamides and their use for treatment of inflammation or pain'19763,965,110'2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles'19763,963,780'N,N\'-disubstituted-p-phenylenediamines'19763,934,034'Hydroxy substituted diphenylalkyls for treatment of lipidemia'19763,932,481'Sulfuric acid esters of bis-(4-hydroxyphenyl)-methane'1976Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1976–1985Patents assigned to SANDOZ AG (9)· patent assignee history
1976–1985Based in Mountain Lakes, NJ, US· patent location history
1980Patents assigned to BRUNSWICK CORP (1)· patent assignee history
1980Based in Cockeysville, MD, US· patent location history
1981Based in Thousand Oaks, CA, US· patent location history
1987–1988Patents assigned to CANNON INSTR COMPANY (2)· patent assignee history
1987–1988Based in Boalsburg, PA, US· patent location history
1990–2006Patents assigned to SEARLE & CO (49)· patent assignee history
1990–2006Based in St. Louis, MO, US· patent location history
2002Patents assigned to PHARMACIA CORP (2)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| SEARLE & CO | 49 | 1990–2006 |
| SANDOZ AG | 9 | 1976–1985 |
| CANNON INSTR COMPANY | 2 | 1987–1988 |
| PHARMACIA CORP | 2 | 2002 |
| BRUNSWICK CORP | 1 | 1980 |
Locations
| Location | Patents | Span |
|---|---|---|
| St. Louis, MO, US | 55 | 1990–2006 |
| Mountain Lakes, New Jersey, US | 10 | 1976–1985 |
| Boalsburg, Pennsylvania, US | 2 | 1987–1988 |
| Thousand Oaks, California, US | 1 | 1981 |
| Cockeysville, Maryland, US | 1 | 1980 |