Inventor

Xandra O. Breakefield

Inventor

Newton, MA, US

Overview

27→

Patents

1990–2020

Patent span

Chemistry

Primary field (CPC C)

Patents· 27 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

A61Kprimary

A61KPreparations for medical, dental or toiletry purposes27%

C12NMicroorganisms or enzymes27%

C07KPeptides8%

C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms8%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations6%

Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests6%

A01KAnimal husbandry5%

C12YEnzymes5%

Y02ATechnologies for adaptation to climate change5%

G01NInvestigating or analysing materials by determining their chemical or physical properties3%

PatentTitleYear

10,793,914Cancer-related biological materials in microvesicles2020 10,407,728Use of microvesicles in analyzing nucleic acid profiles2019 9,879,254'Targeting RNAs to microvesicles'2018 9,829,483Methods of isolating extracellular vesicles2017 9,644,215'AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors'2017 7,655,224'Neural stem cells and use thereof for brain tumor therapy'2010 7,393,526'Systemic gene delivery vehicles for the treatment of tumors'2008 7,186,409'Neural stem cells and use thereof for brain tumor therapy'2007 6,921,814'Torsin, torsin-related genes and methods of detecting neuronal disease'2005 6,770,632'Folypolyglutamyl synthetase gene transfer to enhance antifolate'2004 6,677,155'Triple hybrid amplicon vector systems to generate retroviral packaging lines'2004 6,673,602'Herpes simplex virus amplicon vector targeting system and method of using same'2004 6,610,287'Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication'2003 6,602,499'Combination viral-based and gene-based therapy of tumors'2003 6,573,090'Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors'2003 6,555,108'Implanting HSV-TK retrovirus producing cells to treat tumors'2003 6,537,541'Implantation of HSV-TK retrovirus producer cells to destroy glioma'2003 6,387,616'Torsin, torsin genes, and methods of use'2002 6,262,250'Kits for detecting polymorphisms associated with familial dysautonomia'2001 5,998,133'Use of genetic markers to diagnose familial dysautonomia'1999 5,965,441'HSV/AAV hybrid amplicon vectors'1999 5,783,680'Genetic diagnosis and treatment for impulsive aggression'1998 5,688,773'Method of selectively destroying neoplastic cells'1997 5,501,979'Herpes simplex virus type I expression vector'1996 5,407,821'Genetic diagnosis of torsion dystonia'1995 5,030,570'DNA encoding and method of expressing human monoamine oxidase type A'1991 4,948,590'Avidin or streptavidin conjugated liposomes'1990

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1990–2020Based in Newton, MA, US· patent location history

1991–2017Based in Newton Center, MA, US· patent location history

1995–2010Patents assigned to GEN HOSPITAL CORP (17)· patent assignee history

1997Patents assigned to DANA FARBER CANCER INST INC (1)· patent assignee history

2007–2010Patents assigned to UNIV NORTHEASTERN OHIO (2)· patent assignee history

2008–2010Patents assigned to CHILDRENS MEDICAL CENTER (2)· patent assignee history

2017–2020Patents assigned to MASSACHUSETTS GEN HOSPITAL (5)· patent assignee history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
GEN HOSPITAL CORP	17	1995–2010
MASSACHUSETTS GEN HOSPITAL	5	2017–2020
CHILDRENS MEDICAL CENTER	2	2008–2010
UNIV NORTHEASTERN OHIO	2	2007–2010
DANA FARBER CANCER INST INC	1	1997

Locations

Location	Patents	Span
Newton, Massachusetts, US	22	1990–2020
Newton Center, Massachusetts, US	5	1991–2017