Inventor
Otto W. Woltersdorf, Jr.
Inventor
Chalfont, PA, US
Overview
Patents· 78 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C07Dprimary
C07DHeterocyclic compounds46%
C07CAcyclic or carbocyclic compounds31%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations14%
A61KPreparations for medical, dental or toiletry purposes5%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium2%
A01NPreservation of bodies of humans or animals or plants or parts thereof1%
C07BGeneral methods of organic chemistry1%
PatentTitleYear
4,835,313'(5,6-dichloro-3-oxo-9.alpha.-propyl-2,3,9,9.alpha.-tet rahydrofluoren-7-yl) alkanimidamides'19894,797,391'((5,6-dichloro-3-oxo-9,9a-d isubstituted-2,3,9,9a-tetrahydrofluoren-7-yl)oxy)alkanoic acids and alkanimidamides'19894,777,281'[3,4-dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-substituted-2-phenanthreny l)oxy]-alkanoic acids and -ethanimidamides'19884,775,695'Substituted amidinoalkoxy and amidinoalkylamino indanones and salts thereof'19884,769,370'(1,2-dichloro-8-oxo-5a-substituted-5a,6,7,8 -tetrahydrodibenzofuran-3-yl)alkanoic acids and alkanimidamides'19884,754,061'Substituted (2,3-dihydro-1-oxo-1H-inden-5-yl)alkanoic acids, their derivatives and their salts'19884,751,244'Compounds useful in treating sickle cell anemia'19884,731,471'(5,6-dichloro-3-oxo-2,3,9,9a-tetrahydrofluoren-7-yl)-alkanoic acids and alkanimidamides bearing novel functional 9a-substituents'19884,731,473'Compounds useful in treating sickle cell anemia'19884,731,472'(5,6-dichloro-3-oxo-9A-propyl-2,3,9,9A-tetrahydrofluoren-7-yl)alkanoic acids and alkanimidamides'19884,731,470'[(5,6-dichloro-3-oxo-2,9a-alkano-2,3,9,9a-tetrahydro-1H-fluoren-7-yl)oxy] alkanoic acids and alkanimidamides'19884,731,381'Method of treating a person for sickle cell anemia'19884,719,310'Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts'19884,699,926'Compounds useful in treating sickle cell anemia'19874,680,414'Substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones'19874,654,365'2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury'19874,634,717'Substituted-3- (2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, useful for treating persons with gray matter edema'19874,625,047'Substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy) alkanoic acids, their derivatives and their salts'19864,605,663'Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-dione s, for treatment of grey matter edema'19864,605,664'Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-dione s for treatment of grey matter edema'19864,604,396'[(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimida mides and [(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimid ic acid hydrazides, their derivatives and their salts'19864,604,403'Use of substituted-3(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treating grey matter edema'19864,596,821'Treatment of gray matter edema with 3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones'19864,579,869'Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic acids, their derivatives and their salts'19864,505,923'Ethers of hydroxybenzothiazole-2-sulfonamide for the topical treatment of elevated intraocular pressure'19854,500,538'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19854,472,417'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19844,472,418'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19844,470,991'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19844,465,850'Treatment of brain injury due to gray matter edema with (indanyloxy) butanoic acids'19844,456,599'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19844,454,148'5-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure'19844,426,388'5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19844,416,890'Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure'19834,401,669'2,3-Dihydro-substituted-5-benzoyl benzofuran-2-carboxylic acids and their use in treating hypertension'19834,386,098'6-Hydroxy-2-benzothiazolesulfonamide for the topical treatment of elevated intraocular pressure'19834,317,822'3-Amino-5-substituted-6-halo-N-(3,4-dihydro- 6-substituted-1,3,5-triazin-2-yl)2-pyrazinecarboxamides'19824,296,122'2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids'19814,291,050'6,7-Disubstituted-2 or 2,2-substituted-5-substituted-1-indanones'19814,277,602'3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6 -substituted-1,3,5-truazin-2-yl)2-pyrazinecarboxamides'19814,272,537'3-Amino-5-substituted-6-halo-N-(4,4-disubs tituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides'19814,249,021'Indanacetic acid compounds'19814,246,406'Heterocyclic substituted pyrazinoylguanidines'19814,226,867'3,3-Substituted spiro-1,2,4-benzothiadiazines'19804,224,447'Novel pyrazinecarboxamides and processes for preparing same'19804,208,413'N-Pyrazinecarbonyl-N\'-alkoxycarbonyl and N\',N\"-bis(alkoxycarbonyl)guanidines and processes for preparing same'19804,196,292'6-Substituted amiloride derivatives'19804,189,496'2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid'19804,182,764'Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy(or thio)]alkanoic acids'19804,181,727'2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids'19804,177,285'[1-Oxo-2-thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids and derivatives thereof'19794,163,781'3-Amino-N-[(phosphonoamino)iminomethyl]-6-halopyrazinecarboxamide compounds, compositions and methods of use'19794,163,794'2,3-Dihydro-6,7-disubstituted-5-furoyl benzofuran-2-carboxylic acids'19794,154,742'Certain 5-substituted or unsubstituted phenyl or furyl benzofuran 2-carboxylic acids'19794,145,551'Pyrazine-2-carbonyloxyguanidines'19794,140,776'N-pyrazinecarbonyl-N\'-acylguanidines'19794,115,402'2,3-Dichloro-4-[(substituted-sulfonyl)-phenoxy]-acetic acids'19784,115,573'N-pyrazinecarbonyl-N\'-substituted-sulfamoylguanidine and processes for preparing same'19784,100,294'5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives'19784,096,267'(1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof'19784,087,526'(3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens'19784,087,542'2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids'19784,085,211'Pyrazinecarboxamides and processes for preparing same'19784,085,117'6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids'19784,085,219'1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids'19784,081,554'1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkano acids'19784,070,539'[1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid'19784,012,524'[1-Hydroxy-5-indanyloxy (or thio)]-alkanoic acids'19774,006,180'[1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids'19774,003,927'(1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy ) acetic acids and derivatives'19773,984,465'1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids'19763,984,552'6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids'19763,976,681'[1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids'19763,976,686'[1-Oxo-2,3-hydrocarbylene-5-indanyloxy(or thio)]alkanoic acids'19763,974,212'[1-Hydroximino-2,2-disubstituted-5-indanyloxy-(or thio)]alkanoic acids'19763,966,966'Pharmaceutical compositions and method of treatment employing 1,3-dioxo-2,2-disubstituted indanyloxy alkanoic acids'19763,953,476'3-Amino-5-sulfonylbenzoic acids'19763,931,239'6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids'1976Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1976–1989Patents assigned to MERCK & CO INC (78)· patent assignee history
1976–1989Based in Chalfont, PA, US· patent location history
1988Patents assigned to UNIV PITTSBURGH (3)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| MERCK & CO INC | 78 | 1976–1989 |
| UNIV PITTSBURGH | 3 | 1988 |
Locations
| Location | Patents | Span |
|---|---|---|
| Chalfont, Pennsylvania, US | 78 | 1976–1989 |