Inventor
Owen W. Griffith
Inventor
Milwaukee, WI, US
Overview
Patents· 42 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Kprimary
A61KPreparations for medical, dental or toiletry purposes33%
C07CAcyclic or carbocyclic compounds28%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations20%
Y02ATechnologies for adaptation to climate change6%
C07KPeptides5%
C07DHeterocyclic compounds4%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium1%
C09FNatural resins1%
C12YEnzymes1%
PatentTitleYear
7,022,737'Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses'20066,617,355'Treating asthma by preventing and/or accomodating S-nitrosothiol breakdown'20036,608,110'Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses'20036,359,004'Manipulating nitrosative stress to upregulate nitrosative stress defenses'20026,231,894'Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase'20016,180,824'Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically, proliferating cells or to upregulate nitrosative stress defenses'20016,127,420'L-N.sup.5 -(1-imino-3-alkenyl) ornithine and related compounds and use thereof'20006,057,367'Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses'20005,776,979'Method of use of cardiotonic drugs and inhibitors of nitric oxide synthesis to alleviate pathologic hypotension'19985,770,623'Argine antagonists for inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor'19985,723,448'Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction'19985,695,751'Enhancing delivery of large neutral amino acid drugs'19975,663,364'Heme binding compounds and use thereof'19975,545,625'Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction'19965,534,545'Parenteral amino acid formulations for the inhibition of systemic hypotension associated with nitric oxide production'19965,523,084'Enhancing the anti-tumor effect of melphalan by prior administration of L-amino acid oxidase with or without intermediate administration of anti-L-amino acid oxidase antibody'19965,476,871'Method for the treatment of hypotension induced by a cytokine or bacterial endotoxin using s-alkyl- isothioureido-amino acids'19955,464,858'Heme binding compounds and use thereof'19955,453,441'Substituted arginines and substituted homoarginines and use thereof'19955,436,271'N.sup.6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body'19955,424,447'Heme binding compounds and use thereof'19955,419,901'Use of arginase to control nitric oxide formation'19955,407,672'Enhancing the anti-tumor effect of melphalan with L-amino acid oxidase'19955,395,612'Method for treating systemic hypotension caused by sepsis or cytokine using arginase in combination with an .alpha..sub.1 adrenergic agonist'19955,374,651'Methods and compositions for the treatment of hypotension with arginine free essential and essential amino acids and arginine derivatives'19945,364,881'S-alkyl-isothioureido-amino acids and use thereof'19945,334,380'Anti-endotoxin, interleukin-1 receptor antagonist and anti-tumor necrosis factor antibody with arginine-free formulations for the treatment of hypotension'19945,312,835'Use of cardiotonic drugs and inhibitors of nitric oxide synthesis to alleviate pathologic hypotension'19945,294,736'L-buthionine-S-sulfoximine and methods of making'19945,286,739'Parenteral formulations for the inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor'19945,281,627'Substituted arginines and substituted homoarginines and use thereof'19945,273,875'N.sup.6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body'19935,245,077'L-buthionine-S-sulfoximine and methods of making'19935,196,195'Use of arginase to control nitric oxide formation'19935,171,885'L-buthionine-S-sulfoximine and L-buthionine-R-sulfoximine'19925,158,883'Method of using aminoarginine to block nitric oxide formation in vitro'19925,132,453'N.sup.6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body'19925,093,478'Preparing glutathione monoesters'19925,059,712'Isolating aminoarginine and use to block nitric oxide formation in body'19915,028,627'Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor'19915,011,964'Novel diacylglycerophosphoric acid esters and use thereof as substrates in enzyme assays'19914,781,863'Aminocarnitines'1988Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1988–2001Patents assigned to CORNELL RES FOUNDATION INC (26)· patent assignee history
1988–1996Based in New York, NY, US· patent location history
1991–1998Patents assigned to UNIV TEXAS (8)· patent assignee history
1994–2003Patents assigned to WISCONSIN MED COLLEGE INC (12)· patent assignee history
1994–2006Based in Milwaukee, WI, US· patent location history
1995–2006Patents assigned to UNIV DUKE (10)· patent assignee history
2001Patents assigned to MEDICAL COLLEGE OF WISCONSIN (1)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| CORNELL RES FOUNDATION INC | 26 | 1988–2001 |
| WISCONSIN MED COLLEGE INC | 12 | 1994–2003 |
| UNIV DUKE | 10 | 1995–2006 |
| UNIV TEXAS | 8 | 1991–1998 |
| MEDICAL COLLEGE OF WISCONSIN | 1 | 2001 |
Locations
| Location | Patents | Span |
|---|---|---|
| Milwaukee, WI, US | 26 | 1994–2006 |
| New York, New York, US | 16 | 1988–1996 |