Inventor
Edward J. Olhava
Inventor
Newton, MA, US
Overview
Patents· 39 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Pprimary
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations28%
A61KPreparations for medical, dental or toiletry purposes21%
C07DHeterocyclic compounds19%
C07HSugars11%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium5%
C07CAcyclic or carbocyclic compounds4%
Y02ATechnologies for adaptation to climate change4%
C07BGeneral methods of organic chemistry3%
C07KPeptides1%
C40BCombinatorial chemistry1%
PatentTitleYear
11,072,612NLRP3 modulators202110,968,247Methods of synthesizing substituted purine compounds202110,961,270Compounds and compositions for treating conditions associated with sting activity202110,881,680Method of treating leukemia202110,723,756Cyclic dinucleotides for treating conditions associated with STING activity such as cancer202010,604,542Cyclic dinucleotides for treating conditions associated with sting activity such as cancer202010,556,903NLRP3 modulators202010,533,005NLRP3 modulators202010,273,223Substituted 6,5-fused bicyclic heteroaryl compounds201910,112,968Inhibitors of protein methyltransferase DOT1L and methods of use thereof20189,738,679'Methods of synthesizing substituted purine compounds'20179,718,788'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20179,701,707'Methods of synthesizing substituted purine compounds'20179,637,472'Substituted 6,5-fused bicyclic heteroaryl compounds'20179,597,348'Method of treating leukemia'20179,458,108'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20169,394,310'Carbocycle-substituted purine and 7-deazapurine compounds'20169,206,157'Substituted 6,5-fused bicyclic heteroaryl compounds'20159,175,032'Methods of synthesizing substituted purine compounds'20159,150,525'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20159,145,438'7-deazapurine modulators of histone methyltransferase, and methods of use thereof'20159,096,634'Substituted purine and 7-deazapurine compounds'20159,029,343'Modulators of histone methyltransferase, and methods of use thereof'20158,962,620'Substituted 6,5-fused bicyclic heteroaryl compounds'20158,901,136'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20148,871,745'Proteasome inhibitors'20148,772,536'Proteasome inhibitors'20148,722,877'7-deazapurine modulators of histone methyltransferase, and methods of use thereof'20148,598,167'Substituted 6,5-fused bicyclic heteroaryl compounds'20138,580,762'Substituted purine and 7-deazapurine compounds'20138,530,694'Proteasome inhibitors'20138,481,550'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20138,207,177'Inhibitors of E1 activating enzymes'20128,008,307'Heteroaryl compounds useful as inhibitors of E1 activating enzymes'20118,003,819'Proteasome inhibitors'20117,951,810'Substituted pyrrolo[2,3-d]pyrimidines as inhibitors of E1 activating enzymes'20117,838,673'Proteasome inhibitors'20107,687,662'Proteasome inhibitors'20107,442,830'Proteasome inhibitors'2008Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
2008–2012Based in Cambridge, MA, US· patent location history
2010–2017Patents assigned to MILLENNIUM PHARM INC (14)· patent assignee history
2010–2021Based in Newton, MA, US· patent location history
2011Based in Brookline, MA, US· patent location history
2012–2016Patents assigned to OLHAVA EDWARD J (6)· patent assignee history
2013–2021Patents assigned to EPIZYME INC (18)· patent assignee history
2013–2016Patents assigned to CHESWORTH RICHARD (4)· patent assignee history
2020–2021Patents assigned to INNATE TUMOR IMMUNITY INC (6)· patent assignee history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| EPIZYME INC | 18 | 2013–2021 |
| MILLENNIUM PHARM INC | 14 | 2010–2017 |
| INNATE TUMOR IMMUNITY INC | 6 | 2020–2021 |
| OLHAVA EDWARD Jself | 6 | 2012–2016 |
| CHESWORTH RICHARD | 4 | 2013–2016 |
Locations
| Location | Patents | Span |
|---|---|---|
| Newton, Massachusetts, US | 34 | 2010–2021 |
| Cambridge, Massachusetts, US | 4 | 2008–2012 |
| Brookline, Massachusetts, US | 1 | 2011 |