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Inventor

K. Dane Wittrup

Inventor
Chestnut Hill, MA, US

Overview

41→
Patents
1998–2021
Patent span
Chemistry
Primary field (CPC C)

Patents· 41 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Kprimary
C07KPeptides30%
A61KPreparations for medical, dental or toiletry purposes14%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations14%
C40BCombinatorial chemistry14%
C12NMicroorganisms or enzymes13%
G01NInvestigating or analysing materials by determining their chemical or physical properties13%
B01DSeparation1%
B01JChemical or physical processes, e.g. catalysis or colloid chemistry1%
B82YSpecific uses or applications of nanostructures1%
C12PFermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture1%
PatentTitleYear
11,096,989Synergistic tumor treatment with an extended pharmacokinetic IL-2 and integrin-binding-Fc fusion protein202111,008,383Rationally designed, synthetic antibody libraries and uses therefor202111,008,568Rationally designed, synthetic antibody libraries and uses therefor202110,988,534Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof202110,888,603Methods of treating cancer cells expressing tumor-associated integrins202110,787,500Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species202010,684,289Polyclonal mixtures of antibodies, and methods of making and using them202010,603,358Combination tumor treatment with an integrin-binding-Fc fusion protein and immune stimulator202010,350,266Method of treating cancer with a multiple integrin binding Fc fusion protein201910,196,635Rationally designed, synthetic antibody libraries and uses therefor201910,189,894Rationally designed, synthetic antibody libraries and uses therefor201910,166,273Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein20199,844,582Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents20179,464,136'Antibody-based constructs directed against tyrosine kinase receptors'20169,139,637'Yeast cell surface display of proteins and uses thereof'20158,906,356'Mutant interleukin-2 (IL-2) polypeptides'20148,877,688'Rationally designed, synthetic antibody libraries and uses therefor'20148,815,237'Aglycosylated immunoglobulin mutants'20148,691,730'Rationally designed, synthetic antibody libraries and uses therefor'20148,652,473'Antibodies to EGF receptor epitope peptides and uses thereof'20148,648,176'Engineered proteins with high affinity for DOTA chelates'20148,450,247'Cell display libraries'20138,394,924'Directed engagement of activating Fc receptors'20138,372,636'Yeast cell surface display of proteins and uses thereof'20138,349,311'Mutant interleukin-2 (IL-2) polypeptides'20138,247,531'Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor'20127,951,360'Mutant interleukin-2 (IL-2) polypeptides'20117,767,792'Antibodies to EGF receptor epitope peptides'20107,626,011'Antibodies against tumor surface antigens'20097,569,357'High affinity TCR proteins and methods'20097,569,215'Mutant interleukin-2 (IL-2) polypeptides'20097,465,787'Yeast cell surface display of proteins and uses thereof'20087,413,737'Anti-hydroxylase antibodies and uses thereof'20087,232,888'Antibodies against tumor surface antigens'20076,759,243'High affinity TCR proteins and methods'20046,699,658'Yeast cell surface display of proteins and uses thereof'20046,696,251'Yeast cell surface display of proteins and uses thereof'20046,423,538'Yeast cell surface display of proteins and uses thereof'20026,331,391'Yeast cell surface display of proteins and uses thereof'20016,300,065'Yeast cell surface display of proteins and uses thereof'20015,773,245'Methods for increasing secretion of overexpressed proteins'1998

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1998–2001Based in Urbana, IL, US· patent location history
2001–2015Patents assigned to UNIV ILLINOIS (9)· patent assignee history
2002–2021Based in Chestnut Hill, MA, US· patent location history
2007–2021Patents assigned to MASSACHUSETTS INST TECHNOLOGY (17)· patent assignee history
2007–2021Based in Cambridge, MA, US· patent location history
2012–2014Patents assigned to WITTRUP K DANE (8)· patent assignee history
2013–2016Patents assigned to WITTRUP KARL DANE (4)· patent assignee history
2014–2021Patents assigned to ADIMAB LLC (8)· patent assignee history
2020–2021Based in Lebanon, NH, US· patent location history
2020–2021Based in Boston, MA, US· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
MASSACHUSETTS INST TECHNOLOGY172007–2021
UNIV ILLINOIS92001–2015
ADIMAB LLC82014–2021
WITTRUP K DANEself82012–2014
WITTRUP KARL DANEself42013–2016
Locations
LocationPatentsSpan
Chestnut Hill, Massachusetts, US272002–2021
Lebanon, NH, US42020–2021
Cambridge, Massachusetts, US42007–2021
Urbana, Illinois, US31998–2001
Boston, Massachusetts, US22020–2021