Inventor

Daniel L. Comins

Inventor

Cary, NC, US

Overview

1992–2013

Patent span

Chemistry

Primary field (CPC C)

Patents· 41 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

C07Dprimary

C07DHeterocyclic compounds59%

C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium18%

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations9%

A61KPreparations for medical, dental or toiletry purposes5%

B23KSoldering or unsoldering2%

C07BGeneral methods of organic chemistry2%

C07CAcyclic or carbocyclic compounds2%

C08LCompositions of macromolecular compounds2%

C12PFermentation or enzyme-using processes to synthesise a desired chemical compound or composition or to separate optical isomers from a racemic mixture2%

H05HPlasma technique2%

PatentTitleYear

8,389,732'Synthesis and regioselective substitution of 6-halo- and 6-alkoxy nicotine derivatives'2013 7,888,512'Synthesis of nicotine derivatives from nicotine'2011 7,875,724'Regiospecific synthesis of nicotine derivatives'2011 7,820,826'Synthesis and regioselective substitution of 6-halo-and 6-alkoxy nicotine derivatives'2010 7,671,209'Regiospecific synthesis of nicotine derivatives'2010 7,553,968'Synthesis of nicotine derivatives from nicotine'2009 7,501,520'Regioselective halogenation of nicotine and substituted nicotines'2009 7,361,768'Synthesis of nicotine derivatives from nicotine'2008 7,304,160'Regiospecific synthesis of nicotine derivatives'2007 7,179,917'Regioselective halogenation of nicotine and substituted nicotines'2007 7,132,545'Synthesis of nicotine derivatives from nicotine'2006 7,112,678'Regiospecific synthesis of nicotine derivatives'2006 7,067,672'Regioselective halogenation of nicotine and substituted nicotines'2006 6,995,265'Synthesis of nicotine derivatives from nicotine'2006 6,987,189'Short synthesis of pyridine-based pharmaceutical intermediates'2006 6,855,825'Short synthesis of pyridine-based pharmaceutical intermediates'2005 6,821,982'Preparation of a camptothecin derivative by intramolecular cyclisation'2004 6,706,884'Short synthesis of pyridine-based pharmaceutical intermediates'2004 6,559,309'Preparation of a camptothecin derivative by intramolecular cyclisation'2003 6,534,656'Short synthesis of pyridine-based pharmaceutical intermediates'2003 6,462,196'Preparation of a camptothecin derivative by intramolecular cyclization'2002 6,063,923'Preparation of a camptothecin derivative by intramolecular cyclisation'2000 5,496,952'Method of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogs'1996 5,486,615'Method of making asymmetric DE ring intermediates for the synthesis of camptothecin analogs'1996 5,478,943'Method of making intermediates for camptothecin and its analogs'1995 5,475,108'Camptothecin intermediates and method of making camptothecin and comptothecin analogs'1995 5,459,269'14-halo-camptothecins'1995 5,428,166'Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs'1995 5,395,939'Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs'1995 5,321,140'Pyridinecarboxaldehyde D-ring intermediates useful for the synthesis of camptothecin and camptothecin analogs'1994 5,315,007'Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs'1994 5,264,579'D ring intermediates for the synthesis of camptothecin and camptothecin analogs'1993 5,262,571'Cycloalkyl-based chiral auxiliaries and method making the same'1993 5,258,516'Optically pure D,E ring intermediates useful for the synthesis of camptothecin and camptothecin analogs'1993 5,254,690'Alkoxymethylpyridine d-ring intermediates useful for the synthesis of camptpthecin and camptothecin analogs'1993 5,247,089'Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs'1993 5,243,050'Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs'1993 5,212,317'Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs'1993 5,200,524'Camptothecin intermediates and method of making same'1993 5,191,082'Camptothecin intermediate and method of making camptothecin intermediates'1993 5,162,532'Intermediates and method of making camptothecin and camptothecin analogs'1992

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1992–2013Patents assigned to UNIV NORTH CAROLINA STATE (37)· patent assignee history

1992–2011Based in Cary, NC, US· patent location history

1993Patents assigned to NC STATE UNIVERSITY (1)· patent assignee history

2000Patents assigned to GLAXO WELLCOME INC (1)· patent assignee history

2002–2004Patents assigned to OSI PHARM INC (3)· patent assignee history

2002–2013Based in Raleigh, NC, US· patent location history

2013Patents assigned to COMINS DANIEL L (1)· patent assignee history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
UNIV NORTH CAROLINA STATE	37	1992–2013
OSI PHARM INC	3	2002–2004
COMINS DANIEL Lself	1	2013
GLAXO WELLCOME INC	1	2000
NC STATE UNIVERSITY	1	1993

Locations

Location	Patents	Span
Cary, NC, US	25	1992–2011
Raleigh, NC, US	16	2002–2013