Inventor
Antoni Kozlowski
Inventor
Huntsville, AL, US
Overview
Patents· 131 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
A61Kprimary
A61KPreparations for medical, dental or toiletry purposes29%
C08GMacromolecular compounds obtained otherwise than by reactions only involving unsaturated carbon-to-carbon bonds27%
C08LCompositions of macromolecular compounds13%
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations13%
C07DHeterocyclic compounds6%
C07CAcyclic or carbocyclic compounds4%
Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests3%
C08FMacromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds2%
C07BGeneral methods of organic chemistry2%
C07KPeptides1%
PatentTitleYear
11,111,335Method of preparing carboxylic acid functionalized polymers202110,941,248Methods for preparing functionalized polymers from polymer alcohols202110,894,087Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds202110,844,076Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine202010,759,906Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method202010,682,418Polymer-sunitinib conjugates202010,646,578Polymer derivatives having particular atom arrangements202010,456,476Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)201910,421,838Methods for preparing polymeric reagents and compositions of polymeric reagents201910,220,020Polymer-des-ethyl sunitinib conjugates201910,189,859Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine201910,144,804Method for preparing functionalized polymers from polymer alcohols201810,098,865Multi-arm polymeric prodrug conjugates of taxane-based compounds201810,039,737Multi-arm polymeric alkanoate conjugates201810,035,880Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation201810,011,682Method of preparing carboxylic acid functionalized polymers20189,913,913'Method for preparing a polymeric reagent'20189,908,970'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20189,839,695'Polymer-active agent conjugate'20179,827,326Polymer-sunitinib conjugates20179,732,189'Methods for preparing polymeric reagents and compositions of polymeric reagents'20179,579,392'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20179,504,755'Multi-arm polymeric alkanoate conjugates'20169,433,684'Conjugates of small-interfering nucleic acids'20169,399,070'Compositions comprising a polymeric reagent and a pharmacologically active agent'20169,346,917'Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20169,334,364'Methods for preparing polymeric reagents and compositions of polymeric reagents'20169,333,267'Thiol-selective water-soluble polymer derivatives'20169,308,273'Polymer derivatives comprising an acetal or ketal branching point'20169,308,274'Stabilized polymeric thiol reagents'20169,228,053'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20169,226,969'Salt form of a multi-arm polymer-drug conjugate'20169,220,790'Multi-arm polymeric alkanoate conjugates'20159,199,954'Non-ring hydroxy substituted taxanes and methods for synthesizing the same'20159,173,951'Carbohydrate-based drug delivery polymers and conjugates thereof'20159,173,947'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20159,089,610'Complexes of small-interfering nucleic acids'20159,085,659'Polymer derivatives comprising an imide branching point'20159,045,494'Orthoester compound'20159,044,516'Pharmaceutical compositions of conjugates formed from polymer derivatives having particular atom arrangements'20159,040,658'Thiol-selective water-soluble polymer derivatives'20158,962,566'Multi-arm polymeric alkanoate conjugates'20158,940,801'Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation'20158,916,693'Monoconjugated chitosans as delivery agents for small interfering nucleic acids'20148,901,246'Method for preparing branched functionalized polymers using branched polyol cores'20148,895,759'Intermediates useful in the preparation of maleimide functionalized polymers'20148,865,149'Polymeric reagents comprising a ketone or a related functional group'20148,853,325'Water-soluble polymer alkanals'20148,835,599'Segmented degradable polymers and conjugates made therefrom'20148,835,556'Hydrolytically stable maleimide-terminated polymers'20148,815,227'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20148,816,002'Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20148,809,489'Methods for preparing polymeric reagents and compositions of polymeric reagents'20148,784,849'Hydroxyapatite-targeting poly(ethylene glycol) and related polymers'20148,784,791'Method for preparing water-soluble polymer derivatives bearing an N-succinimidyl ester'20148,765,883'Stabilized polymeric thiol reagents'20148,722,032'Thiol-selective water-soluble polymer derivatives'20148,680,263'Carbohydrate-based drug delivery polymers and conjugates thereof'20148,653,286'Intermediates useful in the preparation of maleimide functionalized polymers'20148,637,466'Multi-arm polymeric alkanoate conjugates'20148,633,277'Methods for forming polymer-drug conjugates'20148,604,159'Method for preparing functionalized polymers from polymer alcohols'20138,568,705'Method for preparing branched functionalized polymers using branched polyol cores'20138,562,965'Polymer derivatives comprising an acetal or ketal branching point'20138,563,651'Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20138,492,503'Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method'20138,492,488'Stabilized polymeric thiol reagents'20138,461,295'Methods for preparing polymeric reagents and compositions of polymeric reagents'20138,440,787'Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom'20138,435,504'Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid'20138,383,380'Segmented polymers and their conjugates'20138,372,422'Hydroxyapatite-targeting poly(ethylene glycol) and related polymers'20138,309,680'Segmented degradable polymers and conjugates made therefrom'20128,304,511'Maleamic acid polymer derivatives and their bioconjugates'20128,299,173'Method involving 1-benzotriazolyl carbonate esters of polymers'20128,258,324'Intermediates useful in the preparation of maleimide functionalized polymers'20128,227,558'Method for preparing polymer maleimides'20128,227,555'Hydrolytically stable maleimide-terminated polymers'20128,217,123'Stabilized polymeric thiol reagents'20128,193,306'Methods for preparing polymeric reagents and compositions of polymeric reagents'20128,182,801'Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid'20128,106,131'Hydrolytically stable maleimide-terminated polymers'20128,084,572'Segmented polymers and their conjugates'20118,076,412'Water-soluble polymer alkanals'20118,067,505'Method of preparing carboxylic acid functionalized polymers'20118,058,385'Method for preparing conjugates using polymer maleimides'20118,039,579'Intermediates useful in the preparation of maleimide functionalized polymers'20118,003,742'Polymer derivatives with proximal reactive groups'20117,994,272'Maleamic acid polymer derivatives and their bioconjugates'20117,977,427'Method involving 1-benzotriazolyl carbonate esters of polymers'20117,947,261'Conjugates formed from polymer derivatives having particular atom arrangements'20117,910,661'Thiol-selective water-soluble polymer derivatives'20117,887,789'Polymer derivatives having particular atom arrangements'20117,872,082'Method for preparing polymer maleimides'20117,851,565'Stabilized polymeric thiol reagents'20107,838,595'Water-soluble polymer alkanals'20107,834,138'Segmented polymers and their conjugates'20107,829,074'Hydroxypatite-targeting poly(ethylene glycol) and related polymers'20107,790,835'Method of preparing maleimide functionalized polymers'20107,767,784'Methods for preparing polymeric reagents and compositions of polymeric reagents'20107,723,432'Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20107,714,088'Poly(ethylene glycol) derivatives with proximal reactive groups'20107,659,361'Maleamic acid polymer derivatives and their bioconjugates'20107,642,323'Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation'20107,608,663'Method of preparing propionic acid-terminated polymers'20097,569,214'Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid'20097,544,738'Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20097,528,202'Poly (ethylene glycol) derivatives with proximal reactive groups'20097,511,094'Water-soluble polymer alkanals'20097,432,331'Hydrolytically stable maleimide-terminated polymers'20087,432,330'Hydrolytically stable maleimide-terminated polymers'20087,378,469'Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20087,329,721'Maleamic acid polymer derivatives and their bioconjugates'20087,223,803'Polyethylene (glycol) derivatives with proximal reactive groups'20077,208,145'Polymeric reagents comprising a ketone or a related functional group'20077,157,546'Water-soluble polymer alkanals'20077,101,932'Method for the preparation of 1-benzotriazolyl carbonate esters of poly (ethylene glycol)'20067,053,150'Segmented polymers and their conjugates'20067,030,278'Polyethylene(Glycol) derivatives with proximal reactive groups'20066,864,327'Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation'20056,774,180'Synthesis of high molecular weight non-peptidic polymer derivatives'20046,710,125'Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20046,664,331'Poly(ethylene glycol) derivatives with proximal reactive groups'20036,624,246'Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)'20036,541,543'Poly (ethylene glycol) derivatives with proximal reactive groups'20036,448,369'Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation'20026,436,386'Hydroxyapatite-targeting poly (ethylene glycol) and related polymers'20026,437,025'Poly(ethylene glycol) derivatives with proximal reactive groups'20026,376,604'Method for the preparation of 1-benzotriazolylcarbonate esters of poly(ethylene glycol)'20026,362,254'Poly(ethylene glycol) derivatives with proximal reactive groups'20025,672,662'Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications'1997Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1997–2021Based in Huntsville, AL, US· patent location history
2003–2009Patents assigned to NEKTAR THERAPEUTICS AL CORP (18)· patent assignee history
2009–2021Patents assigned to NEKTAR THERAPEUTICS (105)· patent assignee history
2011–2021Patents assigned to KOZLOWSKI ANTONI (41)· patent assignee history
2011–2019Patents assigned to SHEN XIAOMING (9)· patent assignee history
2012–2019Patents assigned to MCMANUS SAMUEL P (27)· patent assignee history
2014Based in Huntsvill, AL, US· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| NEKTAR THERAPEUTICS | 105 | 2009–2021 |
| KOZLOWSKI ANTONIself | 41 | 2011–2021 |
| MCMANUS SAMUEL P | 27 | 2012–2019 |
| NEKTAR THERAPEUTICS AL CORP | 18 | 2003–2009 |
| SHEN XIAOMING | 9 | 2011–2019 |
Locations
| Location | Patents | Span |
|---|---|---|
| Huntsville, AL, US | 130 | 1997–2021 |
| Huntsvill, AL, US | 1 | 2014 |