Inventor

Francesco Makovec

Inventor

Monza, IT

Overview

1976–2014

Patent span

Human necessities

Primary field (CPC A)

Patents· 52 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

A61Pprimary

A61PSpecific therapeutic activity of chemical compounds or medicinal preparations39%

C07DHeterocyclic compounds30%

A61KPreparations for medical, dental or toiletry purposes14%

C07CAcyclic or carbocyclic compounds13%

A01NPreservation of bodies of humans or animals or plants or parts thereof1%

A23KFodder1%

A61QSpecific use of cosmetics or similar toiletry preparations1%

C07HSugars1%

C07KPeptides1%

PatentTitleYear

8,809,306'Combination andolast/glucocorticoids'2014 8,633,208'6-1H-imidazo-quinazoline and quinolines derivatives, new MAO inhibitors and imidazoline receptor ligands'2014 8,420,634'Amidine, thiourea and guanidine derivatives of 2-aminobenzothiazoles and aminobenzothiazines for their use as pharmacological agents for the treatment of neurodegenerative pathologies'2013 8,372,866'2-aryl and 2-heteroaryl 4H-1-benzopyran-4-one-6-amidino derivatives, new pharmacological agents for the treatment of arthritis, cancer and related pain'2013 8,258,185'Use of neboglamine in the treatment of toxicodependency'2012 8,193,353'6-1H-imidazo-quinazoline and quinolines derivatives, new potent analgesics and anti-inflammatory agents'2012 7,994,181'6-1H-imidazo-quinazoline and quinolines derivatives, new potent analgesics and anti-inflammatory agents'2011 7,968,558'Amidine derivatives of 2-heteroaryl-quinazolines and quinolines; potent analgesics and anti-inflammatory agents'2011 7,906,551'3-substituted-1,5-diarly-2-alkyl-pyrroles highly selective and orally effective COX-2 inhibitors'2011 7,906,501'Pyrrole derivatives with angiotensin II antagonist activity'2011 7,863,330'Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders'2011 7,846,921'Method of relieving symptoms of gastroesophageal reflux disease'2010 7,824,710'Crystalline and stable form of andolast'2010 7,737,180'Use of neboglamine (CR 2249) as an antipsychotic and neuroprotective'2010 7,674,809'Anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production'2010 7,662,994'Method for the preparation of crystalline dexloxiglumide and products obtained'2010 7,560,591'Benzamidine derivatives having anti-inflammatory and immunosuppressive activity'2009 7,294,648'Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof'2007 7,202,277'Benzamidine derivatives having anti-inflammatory and immunosuppressive activity'2007 7,145,037'Adamantane derivatives with neuroprotective, antidepressant and anti-ischaemic activities, and process for preparing them'2006 6,605,722'Tyrosine derivatives with anti-leukotrienen activity'2003 6,413,978'Basic derivatives of benze isoindol-1-ones and pyrrolo3,4-c quinolin-1-ones with 5-HT3-antagonistic activity, their preparation and their therapeutic use'2002 6,323,216'Basic derivatives of benz[E]isoindol-1-ones and pyrrolo[3,4-c]quinolin-1-ones with 5-HT3-antagonistic activity, their preparation and their therapeutic use'2001 6,156,335'Preparation with an acrylic-based, adhesive copolymeric matrix for the transdermal delivery of estradiol'2000 6,075,033'Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents'2000 5,985,885'Quinazoline-4-amino-2-(piperidine-1-yl-4-substituted) derivatives having antihypertensive activity, a method for their preparation and their pharmaceutical use'1999 5,976,576'Pharmaceutical composition for inhalation containing CR 2039 (Andolast)'1999 5,962,502'Polyamidic acid derivatives with antigastrin activity, a method for their preparation, and their pharmaceutical use'1999 5,922,875'Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use'1999 5,744,607'Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists'1998 5,723,494'Derivatives of glutamic and aspartic acids, a method of preparing them, and their use as drugs for enhancing memory and learning'1998 5,602,179'Optically-active derivatives of (R) 5-pentylamino-5-oxopentanoic acid with antagonistic activity towards cholecystokinin and a method for their preparation'1997 5,587,479'Basic derivatives of glutamic acid and aspartic acid as gastrin or cholecystokinin antagonists'1996 5,500,430'Amidic derivatives of glutamic, aspartic and 2-amino adipic acids, a process for preparing same, and anti-gastrin composition containing the derivatives'1996 5,391,574'Optically-active derivatives of (R) 5-pentylamino-5-oxopentanoic acid with antagonistic activity towards cholecystokinin and a method for their preparation'1995 5,232,937'Derivatives of N-phenylbenzamide with anti-ulcer and anti-allergy'1993 5,130,474'Optically-active derivatives of (R) 5-pentylamino-5-oxopentanoic acid with antagonistic activity towards cholecystokin in and a method for their preparation'1992 4,978,683'Proglumide and pharmaceutical compositions containing it for use in the treatment of neoplastic affections'1990 4,895,856'Derivatives of 5-pentylamino-5-oxopentanoic and 4-pentylamino-4-oxobutanoic acids with antagonistic activity towards cholecystokinin'1990 4,891,383'Derivatives of 5-pentylamino-5-oxopentanoic and 4-pentylamino-4-oxobutanoic acids with antagonistic activity towards cholecystokinin and a method for their preparation'1990 4,891,381'Derivatives of 5-pentylamino-5-oxopentanoil and 4-pentlamino-4-oxobutanoic acids with antagonistic activity towards cholecystokinin'1990 4,870,097'Pharmaceutical use of derivatives of tryptophan'1989 4,826,878'New derivatives of 5-pentylamino-5-oxopentanoic and 4-pentylamino-4-oxobutanoic acids with antagonistic activity towards cholecystokinin'1989 4,791,215'Derivatives of glutamic acid and aspartic acid'1988 4,769,389'Oxygenated-alkyl derivatives of glutamic and aspartic acids with antagonistic activity to bio-active polypeptides and a method for their preparation'1988 4,642,340'Stable compounds of glucosamine sulphate'1987 4,576,951'Proglumide, pharmaceutical preparations and compositions including it for use in human pain relief'1986 4,288,609'Quaternary ammonium derivatives of adamantane with antimicrobic activity'1981 4,272,538'5-Nitro-imidazole with antiprotozoic activity'1981 4,004,008'O-Tertiary amino-alkyl-N-benzoyl tyrosil amides'1977 4,000,297'N-p-chlorobenzoyl tryptophane, salts and compositions thereof'1976 3,985,878'Anti-inflammatory and antirheumatic compounds and preparation'1976

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

1976–2009Patents assigned to ROTTA RESEARCH LAB (33)· patent assignee history

1976–1981Based in Taccona (Milan), IT· patent location history

1981–2009Based in Monza, IT· patent location history

1990Based in Milano, IT· patent location history

2006–2014Based in Lesmo, IT· patent location history

2007–2014Patents assigned to ROTTAPHARM SPA (17)· patent assignee history

2012–2014Patents assigned to GIORDANI ANTONIO (6)· patent assignee history

2012–2014Patents assigned to MAKOVEC FRANCESCO (6)· patent assignee history

2012–2014Patents assigned to ROVATI LUCIO CLAUDIO (6)· patent assignee history

2013Based in Milan, IT· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees

Assignee	Patents	Span
ROTTA RESEARCH LAB	33	1976–2009
ROTTAPHARM SPA	17	2007–2014
GIORDANI ANTONIO	6	2012–2014
MAKOVEC FRANCESCOself	6	2012–2014
ROVATI LUCIO CLAUDIO	6	2012–2014

Locations

Location	Patents	Span
Monza, IT	29	1981–2009
Lesmo, IT	17	2006–2014
Taccona (Milan), IT	4	1976–1981
Milan, IT	1	2013
Milano, IT	1	1990