LexDanaLexDanabeta
Inventor

Gregor James MacDonald

Inventor
Beerse, BE

Overview

73→
Patents
2003–2021
Patent span
Human necessities
Primary field (CPC A)

Patents· 73 as inventor

Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.

A61Pprimary
A61PSpecific therapeutic activity of chemical compounds or medicinal preparations37%
C07DHeterocyclic compounds37%
A61KPreparations for medical, dental or toiletry purposes24%
C07BGeneral methods of organic chemistry1%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium1%
PatentTitleYear
11,071,7291',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1'H-[1,4']bipyridinyl-2'-ones202110,947,242[1,2,4]triazolo[1,5and#8208;A]pyrimidine compounds as PDE2 inhibitors202110,584,129Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors202010,106,542Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors20189,828,3505,6-dihydro-2H-[1,4]oxazin-3-yl-amine derivatives useful as inhibitors of beta-secretase (BACE)20179,751,860'Piperidin-4YL-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists'20179,737,533'1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders'20179,468,640'Piperidin-4-yl-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists'20169,422,296'Fast-dissociating dopamine 2 receptor antagonists'20169,388,175'2-aniline-4-aryl substituted thiazole derivatives'20169,271,967'1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors'20169,266,834'1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors'20169,255,103'Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators'20169,226,930'1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders'20169,181,245'Substituted pyrido[1,2-a]pyrazines and substituted pyrido[1,2-a][1,4]diazepines for the treatment of (inter alia) Alzheimer\'s disease'20159,174,953'Bicyclic thiazoles as allosteric modulators of mGluR5 receptors'20159,132,122'1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones'20159,114,138'1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones'20159,090,632'Bicyclic oxazole and thiazole compounds and their use as allosteric modulators of mGluR5 receptors'20159,085,577'7-aryl-1,2,4-triazolo[4,3-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors'20159,067,891'1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of mGluR2-receptors'20159,040,707'Bicyclic thiazoles as allosteric modulators of mGluR5 receptors'20159,029,366'Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors'20159,012,448'1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors'20158,993,591'1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors'20158,946,426'Substituted bicyclic heterocyclic compounds as gamma secretase modulators'20158,946,205'1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors'20158,940,743'Piperidin-4-yl-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists'20158,937,060'1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders'20158,933,101'Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists'20158,906,939'3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives'20148,906,921'4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists'20148,901,125'Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors'20148,895,562'Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists'20148,865,725'Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors'20148,859,543'Imidazo[1,2-a]pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases'20148,853,237'Naphthyridinone analogs as mGluR5 positive allosteric modulators'20148,841,323'1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors'20148,829,011'2-aminopyrimidine compounds as serotonin receptor modulators'20148,796,311'3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives'20148,791,144'Substituted N-phenyl-1-(4-Pyridinyl)-1H-pyrazol-3-amines'20148,791,120'Fast-dissociating dopamine 2 receptor antagonists'20148,778,974'Trisubstituted 1,2,4 triazoles'20148,779,158'Trisubstituted pyrazoles as acetylcholine receptor modulators'20148,772,504'Substituted benzoxazole, benzimidazole, oxazolopyridine and imidazopyridine derivatives as gamma secretase modulators'20148,748,621'1,3-disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones'20148,722,894'1,3-disubstituted-4-phenyl-1H-pyridin-2-ones'20148,716,282'Imidazo[1,2-b]pyridazine derivatives and their use as PDE10 inhibitors'20148,716,480'7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors'20148,710,074'Dihydronaphthyridinyl(organo)methanone analogs as positive allosteric mGluR5 modulators'20148,691,813'Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors'20148,637,510'Morpholinothiazoles as alpha 7 positive allosteric modulators'20148,592,422'Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors'20138,546,440'Substituted bicyclic imidazole derivatives as gamma secretase modulators'20138,530,474'Substituted 6-(1-piperazinyl)-pyridazines as 5-HT6 receptor antagonists'20138,530,475'Bridged aryl piperazines derivatives useful for the treatment of CNS, GI-urinary and reproductive disorders'20138,466,153'Piperidinylamino-pyridazines and their use as fast dissociating dopamine 2 receptor antagonists'20138,299,101'1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive mGluR2-receptor modulators'20128,252,937'1,3-disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones'20128,236,947'Quinoline derivatives and their use as 5-HT6 ligands'20128,143,419'Trisubstituted 1,2,4-triazoles'20127,977,337'Quinoline derivatives and their use as 5-HT6 ligands'20117,964,602'Biaryl compounds useful as agonists of the Gpr38 receptor'20117,799,774'Quinoline derivatives and their use as 5-HT6 ligands'20107,601,837'Quinoline derivatives and their use as 5-HT6 ligands'20097,538,121'Vanilloid receptor modulators'20097,531,558'Carboxamide derivatives'20097,528,150'Urea derivatives having vanilloid receptor antagonist activity'20097,452,888'Quinoline derivatives and their use as 5-ht6 ligands'20087,439,245'Compounds'20087,429,579'Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents)'20087,262,188'Phenyl sulfone derivatives and their use in the treatment of CNS disorders'20076,605,607'Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents)'2003

Career & activity timeline

Assembled from patent assignee/location history and declaration credentials.

2003–2009Based in Trumpington, GB· patent location history
2007–2012Based in Harlow, GB· patent location history
2012–2016Patents assigned to MACDONALD GREGOR JAMES (41)· patent assignee history
2012–2021Patents assigned to JANSSEN PHARMACEUTICA NV (26)· patent assignee history
2012–2021Patents assigned to JANSSEN PHARMACEUTICALS INC (25)· patent assignee history
2012–2015Patents assigned to TRABANCO-SUAREZ ANDRES AVELINO (13)· patent assignee history
2012–2021Based in Beerse, BE· patent location history
2012–2020Based in Zoersel, BE· patent location history
2014–2021Patents assigned to ADDEX PHARMA SA (12)· patent assignee history
2021Based in Kent, GB· patent location history

Inventor activity

Assignee and location history derived from the patent record.

Assignees
AssigneePatentsSpan
MACDONALD GREGOR JAMESself412012–2016
JANSSEN PHARMACEUTICA NV262012–2021
JANSSEN PHARMACEUTICALS INC252012–2021
TRABANCO-SUAREZ ANDRES AVELINO132012–2015
ADDEX PHARMA SA122014–2021
Locations
LocationPatentsSpan
Beerse, BE322012–2021
Zoersel, BE242012–2020
Harlow, GB112007–2012
Trumpington, GB22003–2009
Kent, GB12021