Inventor
Keith V. Wood
Inventor
Mount Horeb, WI, US
Overview
Patents· 128 as inventor
Public. Assignee & technology derived from the patent record. Each patent links to its LexDana page.
C12Qprimary
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms20%
C12NMicroorganisms or enzymes15%
G01NInvestigating or analysing materials by determining their chemical or physical properties14%
C12YEnzymes10%
C07KPeptides9%
C07DHeterocyclic compounds7%
Y10STechnical subjects covered by former uspc cross-reference art collections [xracs] and digests6%
A61KPreparations for medical, dental or toiletry purposes4%
C07FAcyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium3%
C07CAcyclic or carbocyclic compounds2%
PatentTitleYear
11,028,424Covalent tethering of functional groups to proteins202111,015,216Substituted imidazo[1,2-a]pyrazines as luciferase substrates202110,904,950Proxy based network access202110,844,422Synthetic 202010,774,364Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use202010,745,365Luminogenic and fluorogenic compounds and methods to detect molecules or conditions202010,669,568Substituted imidazo[1,2-a]pyrazines as luciferase substrates202010,648,971Activation of bioluminescence by structural complementation202010,633,690Synthetic oplophorus luciferases with enhanced light output202010,626,349Cleavable surfactants202010,618,907Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements202010,604,745Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule202010,571,471Luciferase-based thermal shift assays202010,550,420Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence202010,501,774Stabilized formulation for luminescent detection of luciferase and nucleoside phosphates201910,408,819Luminescence-based methods and probes for measuring cytochrome P450 activity201910,308,975Substituted imidazo[1,2-a]pyrazines as luciferase substrates201910,288,605Activation of bioluminescence by structural complementation201910,280,447Substituted imidazo[1,2-A]pyrazines tethered to energy acceptors201910,246,690Mutant hydrolase proteins with enhanced kinetics and functional expression201910,240,184Covalent tethering of functional groups to proteins201910,233,485Synthetic oplophorus luciferases with enhanced light output201910,184,936Activation of bioluminescence by structural complementation201910,168,323Compositions and methods for capture of cellular targets of bioactive agents201910,107,800Activation of bioluminescence by structural complementation201810,101,332Covalent tethering of functional groups to proteins and substrates therefor201810,077,433Permuted and nonpermuted luciferase biosensors201810,077,244Luminogenic and fluorogenic compounds and methods to detect molecules or conditions201810,067,149Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer201810,024,862Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer20189,969,991Internal protein tags20189,951,373Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use20189,927,430'Pro-substrates for live cell applications'20189,924,073'Substituted imidazo[1,2-a]pyrazines as luciferase substrates and preparation method thereof'20189,879,306'Luciferase biosensors for cAMP'20189,873,866Mutant dehalogenase proteins20189,869,670'Activation of bioluminescence by structural complementation'20189,840,730'Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use'20179,816,054'Cleavable surfactants'20179,797,890'Activation of bioluminescence by structural complementation'20179,797,889'Activation of bioluminescence by structural complementation'20179,777,311'Synthetic Oplophorus luciferases with enhanced light output'20179,732,373'Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence'20179,676,997'Compositions and methods for stabilizing luminogenic substrates'20179,631,225'Luciferase-based assays'20179,593,316'Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression'20179,574,223'Luminescence-based methods and probes for measuring cytochrome P450 activity'20179,551,705'Compositions and methods for capture of cellular targets of bioactive agents'20179,540,402'Covalent tethering of functional groups to proteins'20179,487,814'Stabilized formulation for luminescent detection of luciferase and nucleoside phosphates'20169,416,353'Covalent tethering of functional groups to proteins and substrates therefor'20169,371,531'Vectors for directional cloning'20169,359,635'Permuted and nonpermuted luciferase biosensors'20169,290,745'Luciferase biosensor'20169,045,730'Luciferase biosensors for cAMP'20159,018,014'Vectors for directional cloning'20158,921,620'Compositions comprising a dehalogenase substrate and a contrast agent and methods of use'20148,895,787'Compositions comprising a dehalogenase substrate and a radionuclide and methods of use'20148,859,220'Luciferase-based assays'20148,822,170'Thermostable luciferases and methods of production'20148,779,221'Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule'20148,765,969'Luminescence-based methods and probes for measuring cytochrome P450 activity'20148,748,148'Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression'20148,742,086'Polynucleotide encoding a mutant dehalogenase to allow tethering to functional groups and substrates'20148,673,558'Luciferase biosensor'20148,669,103'Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use'20148,603,767'Luciferase-based assays'20138,557,970'Synthetic Oplophorus luciferases with enhanced light output'20138,476,450'Luminogenic and fluorogenic compounds and methods to detect molecules or conditions'20138,466,269'Covalent tethering of functional groups to proteins and substrates therefor'20138,420,367'Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression'20138,367,403'Vectors for directional cloning'20138,361,739'Luciferase-based assays'20138,293,503'Vectors for directional cloning'20128,257,939'Compositions comprising a dehalogenase substrate and a fluorescent label and methods of use'20128,202,700'Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule'20128,183,036'Luciferase biosensor'20128,168,405'Covalent tethering of functional groups to proteins and substrates therefor'20128,106,052'Luminescence-based methods and probes for measuring cytochrome P450 activity'20128,071,328'Bioluminescent protease assay'2011RE042931'Covalent tethering of functional groups to proteins'20118,030,017'Thermostable luciferases and methods of production'20118,008,006'Synthetic nucleic acid molecule compositions and methods of preparation'20117,951,550'Luminogenic and fluorogenic compounds and methods to detect molecules or conditions'20117,935,803'Polynucleotides encoding proteins for covalent tethering to functional groups and substrates'20117,906,282'Synthetic nucleic acid molecule compositions and methods of preparation'20117,888,086'Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule'20117,879,540'Synthetic nucleic acid molecule compositions and methods of preparation'20117,867,726'Compositions comprising a dehalogenase substrate and a fluorescent label and methods of use'20117,741,067'Luciferase-based assays'20107,732,128'Kits for detection of ATP'20107,728,118'Synthetic nucleic acid molecule compositions and methods of preparation'20107,692,022'Luminescence-based methods and probes for measuring cytochrome P450 activity'20107,666,987'Bioluminescent caspase assay compounds'20107,537,912'Methods of measuring luminogenic activity with a protected coelenterazine'20097,452,663'Kits for detection of ATP'20087,429,472'Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule'20087,425,436'Covalent tethering of functional groups to proteins and substrates therefor'20087,422,868'Microbial ATP extraction and detection system'20087,384,758'Bioluminescent protease assay with modified aminoluciferin or derivatives thereof'20087,268,229'Compounds to co-localize luminophores with luminescent proteins'20077,241,584'Thermostable luciferases and methods of production'20077,238,842'Covalent tethering of functional groups to proteins'20077,148,030'Bioluminescent protease assay'20067,118,878'Method for increasing luminescence assay sensitivity'20067,108,996'Method for increasing luminescence assay sensitivity'20067,083,911'Method for detection of ATP'20067,078,181'Kits for increasing luminescence assay sensitivity'20066,730,479'Detection of nucleic acid hybrids'20046,703,211'Cellular detection by providing high energy phosphate donor other than ADP to produce ATP'20046,653,078'Multiplex method for nucleic acid detection'20036,602,677'Thermostable luciferases and methods of production'20036,552,179'Mutant luciferases'20036,391,551'Detection of nucleic acid hybrids'20026,387,675'Mutant luciferases'20026,270,974'Exogenous nucleic acid detection'20016,270,973'Multiplex method for nucleic acid detection'20016,235,480'Detection of nucleic acid hybrids'20015,814,471'Luciferase inhibitor compositions and methods of using same'19985,798,263'Apparatus for quantifying dual-luminescent reporter assays'19985,744,320'Quenching reagents and assays for enzyme-mediated luminescence'19985,700,673'Recombinantly produced Coleoptera luciferase and fusion proteins thereof'19975,674,713'DNA sequences encoding coleoptera luciferase activity'19975,670,356'Modified luciferase'19975,650,289'Luciferase assay compositions'19975,641,641'Kit for luciferase assay'19975,583,024'Recombinant expression of Coleoptera luciferase'19965,283,179'Luciferase assay method'1994Career & activity timeline
Assembled from patent assignee/location history and declaration credentials.
1994–2021Patents assigned to PROMEGA CORP (124)· patent assignee history
1994–2020Based in Madison, WI, US· patent location history
1996–1997Based in San Diego, CA, US· patent location history
2006–2021Based in Mount Horeb, WI, US· patent location history
2011–2017Patents assigned to WOOD KEITH V (25)· patent assignee history
2011–2017Patents assigned to KLAUBERT DIETER (13)· patent assignee history
2011–2014Patents assigned to LOS GEORGYI V (8)· patent assignee history
2012–2016Patents assigned to WOOD MONIKA G (10)· patent assignee history
2021Based in Black Diamond, WA, US· patent location history
Inventor activity
Assignee and location history derived from the patent record.
Assignees
| Assignee | Patents | Span |
|---|---|---|
| PROMEGA CORP | 124 | 1994–2021 |
| WOOD KEITH Vself | 25 | 2011–2017 |
| KLAUBERT DIETER | 13 | 2011–2017 |
| WOOD MONIKA G | 10 | 2012–2016 |
| LOS GEORGYI V | 8 | 2011–2014 |
Locations
| Location | Patents | Span |
|---|---|---|
| Mount Horeb, WI, US | 94 | 2006–2021 |
| Madison, WI, US | 31 | 1994–2020 |
| San Diego, California, US | 2 | 1996–1997 |
| Black Diamond, Washington, US | 1 | 2021 |