Described herein are assays directed to determining the level of bioavailable or free vitamin D in a blood sample in a subject. The values determined for bioavailable or free vitamin D indicate whether the subject suffers from insufficient levels of vitamin D. Also described herein are methods of treatment for vitamin D insufficiency.

Claims

8 · 1 independent · depth 3

8 granted claims

›1.independentA method for determining a level of bioavailable vitamin D and a level of free vitamin D in a subject, the method comprising:nperforming assays on a b…+7

›2.↳ 1The method of claim 1, wherein a level of bioavailable vitamin D lower than 25% of the mean value of bioavailable vitamin D in a population of healthy…d2+2

›3.↳ 1The method of claim 1, wherein the vitamin D is selected from the group consisting of: 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D.d2

›4.↳ 1The method of claim 1, wherein the assays to determine the level of VDBP polypeptide or albumin polypeptide comprises use of a method selected from th…d2

›5.↳ 1The method of claim 1, wherein the assays to determine the level of total vitamin D comprises the use of a method selected from the group consisting o…d2

›8.↳ 1The method of claim 1, wherein level of bioavailable vitamin D and the level of free vitamin D are calculated by a processor.d2

Classifications

3 codes

IPC · International Patent Classification

Section G — Physics

G01N31/00
G01N33/82
G01N33/53

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File wrapper

Pendency

4.0 y

1,446 days filing → grant

Office actions

non-final + final

Responses

1 RCE

Examiner

Lisa Cook

art unit 1678 · TC 1600

Law firm

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Citations: 158 back · 0 forward

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Priority chain

2 priority documents

Priority

7 Jan 2011

earliest claimed

›Priority documents — 2

Type	Document	Date
provisional	US 61430643	7 Jan 2011
related publication	US 20140113885 A1	24 Apr 2014

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