Diagnostic method using PALB2
Granted 25 Aug 2015 · 8 office actions
Current assignee: National Institutes of Health · originally Johns Hopkins University
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Inventors: Kenneth W. Kinzler, Michael Goggins, Alison Klein, Sian Jones +7 · Examiner: Stephen Kapushoc · AU 1634 · TC 1600
Life of the patent
4 dated eventsAbstract
The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient\'s response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.
Claims
7 · 1 independent · depth 2Classifications
5 codes- A61P35/00
- C12P19/34
- C12Q1/68
- C07H21/04
- G01N33/574
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2 priority documents›Priority documents — 2
| Type | Document | Date |
|---|---|---|
| provisional | US 61157700 | 5 Mar 2009 |
| related publication | US 20120034318 A1 | 9 Feb 2012 |
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