Provided are novel methods of treating and/or preventing a disease or condition caused by or associated with a virus belonging to the Bunyaviridae or Togaviridae family using iminosugars, such as DNJ derivatives.

Claims

35 · 2 independent · depth 4

35 granted claims

›1.independentA method of treating a disease or condition caused by or associated with a virus belonging to the Bunyaviridae family, the method comprisingnadministe…+15

›2.↳ 1The method of claim 1, wherein R is a C8-C16 alkyl group.d2+2

›5.↳ 1The method of claim 1, wherein R isd2+4

›10.↳ 1The method of claim 1, wherein the subject is a mammal.d2

›11.↳ 1The method of claim 1, wherein the subject is a human being.d2

›12.↳ 1The method of claim 1, wherein the virus is selected from Andes virus; Hantaan virus; Puumala virus; Seoul virus; Sin Nimbre virus; Dugbe virus; Crime…d2

›13.↳ 1The method of claim 1, wherein the virus belongs to Genus Phlebovirus.d2

›14.↳ 1The method of claim 1, wherein the virus is Rift Valley fever virus.d2

›15.↳ 1The method of claim 1, wherein the disease or condition is selected from hemorrhagic fever with renal syndrome; Hantavirus cardiopulmonary syndrome;nN…d2

›16.↳ 1The method of claim 1, wherein the disease or condition is Rift Valley fever.d2

›17.independentA method of treating a disease or condition caused by or associated with a virus belonging to the Togaviridae family, the method comprising administer…+18

›18.↳ 17The method of claim 17, wherein R is a C8-C16 alkyl group.d2+2

›21.↳ 17The method of claim 17, wherein R isd2+4

›26.↳ 17The method of claim 17, wherein the subject is a mammal.d2

›27.↳ 17The method of claim 17, wherein the subject is a human being.d2

›28.↳ 17The method of claim 17, wherein the virus is selected from Sindbis virus; Semliki Forest virus; O⬲nyong'nyong virus; Chikungunya virus; Mayaro virus; …d2

›29.↳ 17The method of claim 17, wherein the virus belongs to Genus Alphavirus.d2

›30.↳ 17The method of claim 17, wherein the virus is Chikungunya virus.d2

›31.↳ 17The method of claim 17, wherein the virus is Venezuelan equine encephalitis virus.d2

›32.↳ 17The method of claim 17, wherein the disease or condition is selected from sindbis fever; O⬲nyong'nyong fever; Chikungunya disease; Ross River fever; B…d2

›33.↳ 17The method of claim 17, wherein the disease or condition is Chikungunya disease.d2

›34.↳ 17The method of claim 17, wherein the disease or condition is equine encephalitis.d2

›35.↳ 17The method of claim 17, wherein the disease or condition is Venezuelan equine encephalitis.d2

Classifications

3 codes

IPC · International Patent Classification

Section A — Human necessities

A61K31/445

USPC · US Patent Classification

514/328514/315

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Pendency

2.7 y

970 days filing → grant

Office actions

non-final + final

Responses

1 RCE

Examiner

Rei-tsang Shiao

art unit 1628 · TC 1600

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Citations: 74 back · 0 forward

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Priority chain

2 priority documents

Priority

12 Jun 2009

earliest claimed

›Priority documents — 2

Type	Document	Date
provisional	US 61186614	12 Jun 2009
related publication	US 20100317696 A1	16 Dec 2010

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