A biocompatible meniscal repair device, comprising;na biocompatible tissue repair scaffold adapted to be placed in contact with a defect in a meniscus, wherein the scaffold comprises a dry laid nonwoven polymeric material, the dry laid nonwoven polymeric material consists of a density in the range of about 120 mg/cc to 360 mg/cc, and wherein the scaffold has an initial modulus of elasticity greater than 1.5 MPa or about 1.5 MPa and an initial suture pull-out strength greater than 6N or about 6 N, and wherein viable tissue is disposed on the tissue repair scaffold, the viable tissue having viable cells capable of integrating with native tissue adjacent to the tissue repair scaffold.
›2.↳ 1The repair device of claim 1, wherein the tissue repair scaffold has an initial peak stress greater than about 2 MPa.d2
The repair device of claim 1, wherein the tissue repair scaffold has an initial peak stress greater than about 2 MPa.
›3.↳ 1The repair device of claim 1, wherein the tissue repair scaffold has an initial suture pull-out strength less than about 45 N.d2
The repair device of claim 1, wherein the tissue repair scaffold has an initial suture pull-out strength less than about 45 N.
›4.↳ 1The repair device of claim 1, wherein the tissue repair scaffold has an initial modulus of elasticity less than about 40 MPa.d2
The repair device of claim 1, wherein the tissue repair scaffold has an initial modulus of elasticity less than about 40 MPa.
›5.↳ 1The repair device of claim 1, wherein the tissue repair scaffold has a thickness in the range of about 0.5 mm to 1.5 mm.d2
The repair device of claim 1, wherein the tissue repair scaffold has a thickness in the range of about 0.5 mm to 1.5 mm.
›6.↳ 1The repair device of claim 1, wherein the tissue repair scaffold further comprises a biocompatible foam material joined to the nonwoven polymeric mate…d2
The repair device of claim 1, wherein the tissue repair scaffold further comprises a biocompatible foam material joined to the nonwoven polymeric material.
›7.↳ 1The repair device of claim 1, the nonwoven polymeric material comprises a synthetic polymer.d2
The repair device of claim 1, the nonwoven polymeric material comprises a synthetic polymer.
›8.↳ 1The repair device of claim 1, wherein the tissue repair scaffold is bioabsorbable.d2
The repair device of claim 1, wherein the tissue repair scaffold is bioabsorbable.
›9.↳ 1The repair device of claim 1, wherein the nonwoven polymeric material is formed from at least one polymer derived from monomers selected from the grou…d2+2
The repair device of claim 1, wherein the nonwoven polymeric material is formed from at least one polymer derived from monomers selected from the group consisting of glycolide, lactide, caprolactone, trimethylene carbonate, polyvinyl alcohol, and dioxanone.
›10.↳ 9The repair device of claim 9, wherein the nonwoven polymeric material comprises polydioxanone.d3
The repair device of claim 9, wherein the nonwoven polymeric material comprises polydioxanone.
›11.↳ 9The repair device of claim 9, wherein the nonwoven polymeric material comprises a copolymer of polyglycolic acid and polylactic acid.d3
The repair device of claim 9, wherein the nonwoven polymeric material comprises a copolymer of polyglycolic acid and polylactic acid.
›12.↳ 1The repair device of claim 1, further comprising at least one bioactive substance effective to stimulate cell growth.d2+1
The repair device of claim 1, further comprising at least one bioactive substance effective to stimulate cell growth.
›13.↳ 12The repair device of claim 12, wherein the bioactive substance is selected from the group consisting of a platelet rich plasma, cartilage-derived morp…d3
The repair device of claim 12, wherein the bioactive substance is selected from the group consisting of a platelet rich plasma, cartilage-derived morphogenic proteins, recombinant human growth factors, and combinations thereof.
›14.↳ 1The repair device of claim 1, wherein the nonwoven polymeric material comprises crimped, synthetic polymer fibers.d2
The repair device of claim 1, wherein the nonwoven polymeric material comprises crimped, synthetic polymer fibers.
›15.↳ 1The repair device of claim 1, wherein the nonwoven polymeric material is heat-set.d2
The repair device of claim 1, wherein the nonwoven polymeric material is heat-set.
›16.↳ 1The repair device of claim 1, wherein the fiber orientation of the nonwoven polymeric material is isotropic.d2
The repair device of claim 1, wherein the fiber orientation of the nonwoven polymeric material is isotropic.
›18.↳ 1The repair device of claim 1, wherein the viable tissue disposed on the tissue repair scaffold is selected from the group consisting of minced tissue,…d2
The repair device of claim 1, wherein the viable tissue disposed on the tissue repair scaffold is selected from the group consisting of minced tissue, sliced tissue, and a tissue strip.
