The invention related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R 1 , R 2 , R 3 , n and m are as described in the specification, useful in the treatment of a [structure] disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.

Claims

17 · 8 independent · depth 3

17 granted claims

›1.independentA method for the treatment of a disease or medical condition in which inhibition of GLK is indicated, comprising administering a compound of Formula (…+2

›3.independentA compound of Formula (Ib) or a salt, solvate or prodrug thereof+5

›9.independentA compound of Formula (II) or a salt, solvate, or prodrug thereof:

›10.independentA compound of Formula (IIa) or a salt, solvate, or prodrug thereof:

›11.independentA compound of Formula (IIf) or a salt, solvate or prodrug thereof:

›12.independentmultiple · 9, 10, 11A compound according to any one of claims 9 to 11 or a salt, solvate or prodrug thereof, whereinnX is independently selected from: â€”O-Z-, SO2N(R6)-Z…

›13.independentmultiple · 3, 9, 10A pharmaceutical composition comprising a compound according to any one of claims 3, 9, 10, or 11 or a salt, solvate or prodrug thereof, together with…+2

›15.independentA process for the preparation of a compound of Formula (I)

Classifications

4 codes

IPC · International Patent Classification

Section A — Human necessities

A61K31/44

Section C — Chemistry; metallurgy

C07D213/75

USPC · US Patent Classification

514/352546/309

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Pendency

4.5 y

1,660 days filing → grant

Office actions

non-final + final

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Examiner

Michael Barker

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1 priority documents

›Priority documents — 1

Type	Document	Date
related publication	US 20040214868 A1	28 Oct 2004

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