Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

Claims

8 · 3 independent · depth 2

8 granted claims

›1.independentAn immunogenic composition comprising an immunostimulant and a polypeptide, wherein the polypeptide comprises at least a 10 amino acid portion of SEQ …+4

›6.independentAn immunogenic composition comprising an immunostimulant and a polypeptide, wherein the polypeptide comprises a sequence having at least 90% identity …

›7.independentAn immunogenic composition comprising an immunostimulant and an antigen-presenting cell that expresses a polypeptide, wherein the polypeptide comprise…+1

Classifications

13 codes

IPC · International Patent Classification

Section C — Chemistry; metallurgy

C07K1/00

USPC · US Patent Classification

530/350530/352536/23.7530/380424/185.1424/184.1435/6424/197.11536/23.1435/91.2435/91.1435/5

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Pendency

2.6 y

959 days filing → grant

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W. Gary Jones

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