USPatentGranted

Compositions and methods for controlling genetically engineered organisms

Granted 26 Sep 2000 · no office action yet

Application
Not granted yet
filed 6 Feb 1998
Publication
Not published
not published
Patent· this page
US 6,124,129
granted 26 Sep 2000

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Abstract

Compositions and methods for the control of genetically engineered organisms are described. A more effective cell suicide approach is contemplated based on the conditional expression of the lethal Streptomyces avidinii streptavidin gene. Toxicity of streptavidin is derived from its exceptionally high binding affinity for an essential prosthetic group, D-biotin. The general requirement for biotin through the living world makes streptavidin-based conditional lethal designs applicable to a broad range of containment strategies.

Claims

5 · 1 independent · depth 3
12345
5 granted claims

Classifications

2 codes
USPC · US Patent Classification
435/252.33235/252.3

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Pendency
2.6 y
963 days filing → grant
Office actions
0
on the grant's record
Examiner
Remy Yucel
art unit —
Citations: 3 back · 1 forward

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